Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

A Potential Role for P2X7R in Allergic Airway Inflammation in Mice and Humans

(2010) Tobias Müller et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Resolution of Allergic Inflammation and Airway Hyperreactivity Is Dependent upon Disruption of the T1/ST2–IL-33 Pathway

(2009) Jennifer Kearley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Novel Antiinflammatory Role for Andrographolide in Asthma via Inhibition of the Nuclear Factor-κB Pathway

(2009) Zhang Bao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation of mucin expression in respiratory diseases

(2009) Jonathan Turner et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Fine tuning the immune response with PI3K

(2009) David A. Fruman et al.   IMMUNOLOGICAL REVIEWS

Allergic airway hyperresponsiveness, inflammation, and remodeling do not develop in phosphoinositide 3-kinase γ–deficient mice

(2009) Masahide Takeda et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

PI3Kγ-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling

(2008) Dae Hyun Lim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IL-23 and Th17 Cells Enhance Th2-Cell–mediated Eosinophilic Airway Inflammation in Mice

(2008) Hidefumi Wakashin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

T Cell Trafficking in Allergic Asthma: The Ins and Outs

(2008) Benjamin D. Medoff et al.   Annual Review of Immunology

Eosinophils: Biological Properties and Role in Health and Disease

(2008) SIMON P. HOGAN et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

(2008) J. Hou et al.   CLINICAL CANCER RESEARCH

F.5. RNA Interference-mediated Inhibition of Acidic Mammalian Chitinase Suppresses OVA-sensitized Allergic Asthma

(2008) Ching Jen Yang et al.   CLINICAL IMMUNOLOGY

The Antiviral Activities of Artemisinin and Artesunate

(2008) Thomas Efferth et al.   CLINICAL INFECTIOUS DISEASES

The epidermal growth factor receptor mediates allergic airway remodelling in the rat

(2008) M. Tamaoka et al.   EUROPEAN RESPIRATORY JOURNAL

Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases

(2008) P-R. Burgel et al.   EUROPEAN RESPIRATORY JOURNAL

Essential role of phosphoinositide 3-kinase gamma in eosinophil chemotaxis within acute pulmonary inflammation

(2008) Matthew Thomas et al.   IMMUNOLOGY

Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-κB activation

(2008) Bin Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Aerosolized Phosphoinositide 3-Kinase  /  Inhibitor TG100-115 [3-[2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a Therapeutic Candidate for Asthma and Chronic Obstructive Pulmonary Disease

(2008) J. Doukas et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The development of allergic inflammation

(2008) Stephen J. Galli et al.   NATURE

Artesunate for the Treatment of Severe Falciparum Malaria

(2008) Philip J. Rosenthal   NEW ENGLAND JOURNAL OF MEDICINE

The multiple roles of phosphoinositide 3-kinase in mast cell biology

(2008) Mi-Sun Kim et al.   TRENDS IN IMMUNOLOGY

Artemisinins: their growing importance in medicine

(2008) Sanjeev Krishna et al.   TRENDS IN PHARMACOLOGICAL SCIENCES