Widespread displacement of DNA‐ and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides
出版年份 2021 全文链接
标题
Widespread displacement of DNA‐ and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides
作者
关键词
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出版物
EMBO JOURNAL
Volume -, Issue -, Pages -
出版商
EMBO
发表日期
2021-05-12
DOI
10.15252/embj.2019103311
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phase separation of toxic dipeptide repeat proteins related to C9orf72 ALS/FTD
- (2020) Hamidreza Jafarinia et al. BIOPHYSICAL JOURNAL
- Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
- (2019) Yong-Jie Zhang et al. SCIENCE
- C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function
- (2019) Michael R. White et al. MOLECULAR CELL
- Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model
- (2018) Amrutha Swaminathan et al. HUMAN MOLECULAR GENETICS
- Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents
- (2018) Antonella Borrelli et al. MOLECULES
- Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
- (2018) Yong-Jie Zhang et al. NATURE MEDICINE
- C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten
- (2017) Matthew J. Stopford et al. HUMAN MOLECULAR GENETICS
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
- (2017) Steven Boeynaems et al. MOLECULAR CELL
- Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients
- (2017) Shanye Yin et al. Cell Reports
- Amyotrophic lateral sclerosis
- (2017) Orla Hardiman et al. Nature Reviews Disease Primers
- C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
- (2016) Kyung-Ha Lee et al. CELL
- Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
- (2016) Yi Lin et al. CELL
- The toxicology of heparin reversal with protamine: past, present and future
- (2016) Emilia Sokolowska et al. Expert Opinion on Drug Metabolism & Toxicology
- Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation
- (2016) Kohsuke Kanekura et al. HUMAN MOLECULAR GENETICS
- A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors
- (2016) Sergio Ruiz et al. MOLECULAR CELL
- Poly(GR) in C9ORF72 -Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons
- (2016) Rodrigo Lopez-Gonzalez et al. NEURON
- Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72 -ALS/FTD
- (2016) Thomas Westergard et al. Cell Reports
- Protamine–oligonucleotide-nanoparticles: Recent advances in drug delivery and drug targeting
- (2015) B. Scheicher et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Nuclear accumulation of mRNAs underlies G4C2-repeat-induced translational repression in a cellular model of C9orf72 ALS
- (2015) S. Rossi et al. JOURNAL OF CELL SCIENCE
- C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
- (2015) J. Chew et al. SCIENCE
- Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
- (2014) Xinmei Wen et al. NEURON
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
- (2014) S. Mizielinska et al. SCIENCE
- Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
- (2014) I. Kwon et al. SCIENCE
- A Comparison of DNA Compaction by Arginine and Lysine Peptides: A Physical Basis for Arginine Rich Protamines
- (2013) Jason DeRouchey et al. BIOCHEMISTRY
- Reactive nucleolar and Cajal body responses to proteasome inhibition in sensory ganglion neurons
- (2013) Ana Palanca et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- System-wide identification of RNA-binding proteins by interactome capture
- (2013) Alfredo Castello et al. Nature Protocols
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
- (2013) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- The Cajal Body and Histone Locus Body
- (2010) Z. Nizami et al. Cold Spring Harbor Perspectives in Biology
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