Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver

Liver tissue microbiome in NAFLD: next step in understanding the gut–liver axis?

(2020) Herbert Tilg et al.   GUT

Ghrelin‐insulin‐like growth factor‐1 axis is activated via autonomic neural circuits in the non‐alcoholic fatty liver disease

(2020) Takuro Nagoya et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Serotonin transporter dependent modulation of food-seeking behavior

(2020) Jianzheng He et al.   PLoS One

Prenatal antidepressant exposures and gastrointestinal complaints in childhood: A gut–brain axis connection?

(2020) Amy L. Salisbury et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Western diet‐induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis

(2020) Biki Gupta et al.   FASEB JOURNAL

Diet differentially regulates enterochromaffin cell serotonin content, density and nutrient sensitivity in the mouse small and large intestine

(2020) Alyce M. Martin et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Gut‐brain axis serotonergic responses to acute stress exposure are microbiome‐dependent

(2020) Joshua M. Lyte et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The liver–brain–gut neural arc maintains the Treg cell niche in the gut

(2020) Toshiaki Teratani et al.   NATURE

Modulation of the TPH 1/ MAO ‐A/5 HT /5 HTR 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis

(2019) Konstantina Kyritsi et al.   HEPATOLOGY

Liver sympathetic denervation reverses obesity‐induced hepatic steatosis

(2019) Chansol Hurr et al.   JOURNAL OF PHYSIOLOGY-LONDON

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

(2019) Atsunori Kamiya et al.   NATURE NEUROSCIENCE

Review article: can bugs be drugs? The potential of probiotics and prebiotics as treatment for non-alcoholic fatty liver disease

(2019) Nienke Koopman et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Current Status in Testing for Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH)

(2019) Hannah K. Drescher et al.   Cells

Hypothalamic AMPKα2 regulates liver energy metabolism in rainbow trout through vagal innervation

(2019) Marta Conde-Sieira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives

(2019) Haiming Hu et al.   JOURNAL OF GASTROENTEROLOGY

Intestinal Crosstalk between Microbiota and Serotonin and its Impact on Gut Motility

(2018) Xiaolong Ge et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Assessment of the possible roles of SB-269970 versus ketanserin on carbon tetrachloride-induced liver fibrosis in rats: Oxidative stress/TGF-β 1 -induced HSCs activation pathway

(2018) Marwa Ahmed Amin Atallah et al.   Pharmacological Reports

Autonomic nervous system network and liver regeneration

(2018) Kenya Kamimura et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract

(2018) Ryosuke Inoue et al.   FEBS Open Bio

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

(2018) Bruno Bonaz et al.   Frontiers in Neuroscience

Inhibition of Serotonin Synthesis Induces Negative Hepatic Lipid Balance

(2018) Jun Namkung et al.   Diabetes & Metabolism Journal

ABNORMAL ABSORPTIVE COLONIC MOTOR ACTIVITY IN GERM FREE MICE IS RECTIFIED BY BUTYRATE, AN EFFECT POSSIBLY MEDIATED BY MUCOSAL SEROTONIN

(2018) Alexander D Vincent et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Potentiation of serotonin signaling protects against intestinal ischemia and reperfusion injury in mice

(2018) John J. Tackett et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation

(2018) Tomohito Izumi et al.   Nature Communications

Serotonin signals through a gut-liver axis to regulate hepatic steatosis

(2018) Wonsuk Choi et al.   Nature Communications

Commensal microbiota-induced microRNA modulates intestinal epithelial permeability through the small GTPase ARF4

(2017) Kazuaki Nakata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the gut-liver axis in liver disease

(2017) Reiner Wiest et al.   JOURNAL OF HEPATOLOGY

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

(2016) Jérôme Boursier et al.   HEPATOLOGY

Tropisetron suppresses colitis-associated cancer in a mouse model in the remission stage

(2016) Hossein Amini-Khoei et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

Macrophages and Dendritic Cells Emerge in the Liver during Intestinal Inflammation and Predispose the Liver to Inflammation

(2014) Yohei Mikami et al.   PLoS One

Development of a Prokaryotic Universal Primer for Simultaneous Analysis of Bacteria and Archaea Using Next-Generation Sequencing

(2014) Shunsuke Takahashi et al.   PLoS One

Comparison between terminal-restriction fragment length polymorphism (T-RFLP) and quantitative culture for analysis of infants' gut microbiota

(2013) Fei Sjöberg et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Serotonin Receptor Type 3 Antagonists Improve Obesity-Associated Fatty Liver Disease in Mice

(2011) S. Haub et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Serotonin reuptake transporter (SERT) plays a critical role in the onset of fructose-induced hepatic steatosis in mice

(2009) Synia Haub et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Expanded Biology of Serotonin

(2009) Miles Berger et al.   Annual Review of Medicine

Gut chemosensing: Interactions between gut endocrine cells and visceral afferents

(2009) Helen E. Raybould   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Regulation of Pancreatic   Cell Mass by Neuronal Signals from the Liver

(2008) J. Imai et al.   SCIENCE