An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

(2021) Maya Maor-Nof et al.   CELL

The multiple mechanisms that regulate p53 activity and cell fate

(2019) Antonina Hafner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes

(2019) Margot E. Bowen et al.   DEVELOPMENTAL CELL

Regulation of apoptosis by an intrinsically disordered region of Bcl-xL

(2018) Ariele Viacava Follis et al.   Nature Chemical Biology

Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling

(2016) David J. Simon et al.   CELL

Axonal Degeneration Is Regulated by a Transcriptional Program that Coordinates Expression of Pro- and Anti-degenerative Factors

(2016) Maya Maor-Nof et al.   NEURON

The Transactivation Domains of the p53 Protein

(2016) Nitin Raj et al.   Cold Spring Harbor Perspectives in Medicine

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

(2015) Ariele Viacava Follis et al.   MOLECULAR CELL

Mechanisms of developmental neurite pruning

(2014) Oren Schuldiner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLDS-mediated axon protection independent of axonal mitochondria

(2013) Brandon M. Kitay et al.   HUMAN MOLECULAR GENETICS

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

(2013) Ariele Viacava Follis et al.   Nature Chemical Biology

A Caspase Cascade Regulating Developmental Axon Degeneration

(2012) D. J. Simon et al.   JOURNAL OF NEUROSCIENCE

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

Sensory Neuropathy Attributable to Loss of Bcl-w

(2011) S. L. Courchesne et al.   JOURNAL OF NEUROSCIENCE

p53 at a glance

(2010) C. A. Brady et al.   JOURNAL OF CELL SCIENCE

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE