Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas

Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response

(2020) Xiaodun Yang et al.   DIABETES

The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function

(2019) Jason M. Spaeth et al.   DIABETES

Roles and regulation of histone methylation in animal development

(2019) Ashwini Jambhekar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Murine Perinatal Beta Cell Proliferation and the Differentiation of Human Stem Cell Derived Insulin Expressing Cells Require NEUROD1

(2019) Anthony I. Romer et al.   DIABETES

2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2020

(2019)   DIABETES CARE

Single‐cell transcriptomic analyses reveal distinct dorsal/ventral pancreatic programs

(2018) Lin‐Chen Li et al.   EMBO REPORTS

Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis

(2018) Marissa A. Scavuzzo et al.   Nature Communications

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors

(2018) Nicole A.J. Krentz et al.   Stem Cell Reports

Epigenetics in formation, function, and failure of the endocrine pancreas

(2017) Maria L. Golson et al.   Molecular Metabolism

On the Dependency of Cellular Protein Levels on mRNA Abundance

(2016) Yansheng Liu et al.   CELL

Impact of Pdx1-associated chromatin modifiers on islet β-cells

(2016) J. M. Spaeth et al.   DIABETES OBESITY & METABOLISM

Pancreatic β cell identity requires continual repression of non–β cell programs

(2016) Giselle Domínguez Gutiérrez et al.   JOURNAL OF CLINICAL INVESTIGATION

The Groucho/Transducin-like enhancer of split protein family in animal development

(2015) Megha Agarwal et al.   IUBMB LIFE

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Transcription factor regulation of pancreatic organogenesis, differentiation and maturation

(2015) Reshmi Dassaye et al.   Islets

Dynamic Recruitment of Functionally Distinct Swi/Snf Chromatin Remodeling Complexes Modulates Pdx1 Activity in Islet β Cells

(2015) Brian McKenna et al.   Cell Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Grg3/TLE3 and Grg1/TLE1 Induce Monohormonal Pancreatic β-Cells While Repressing α-Cell Functions

(2014) David E. Metzger et al.   DIABETES

The transcriptional co-repressor TLE3 suppresses basal signaling on a subset of estrogen receptor α target genes

(2014) Maïka Jangal et al.   NUCLEIC ACIDS RESEARCH

The Corepressor Tle4 Is a Novel Regulator of Murine Hematopoiesis and Bone Development

(2014) Justin C. Wheat et al.   PLoS One

The transcriptional co-repressor TLE3 regulates development of trophoblast giant cells lining maternal blood spaces in the mouse placenta

(2013) Malgorzata Gasperowicz et al.   DEVELOPMENTAL BIOLOGY

Generation of mice encoding a conditional allele of Nkx2.2

(2013) Teresa L. Mastracci et al.   TRANSGENIC RESEARCH

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

(2013) Brandon L. Taylor et al.   Cell Reports

Regulation of Neurod1 Contributes to the Lineage Potential of Neurogenin3+ Endocrine Precursor Cells in the Pancreas

(2013) Teresa L. Mastracci et al.   PLoS Genetics

The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and  -cell differentiation

(2012) D. E. Metzger et al.   DEVELOPMENT

TLE3 Is a Dual-Function Transcriptional Coregulator of Adipogenesis

(2011) Claudio J. Villanueva et al.   Cell Metabolism

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Nkx2.2 repressor complex regulates islet  -cell specification and prevents  -to- -cell reprogramming

(2011) J. B. Papizan et al.   GENES & DEVELOPMENT

Epigenetic Mechanisms of Groucho/Grg/TLE Mediated Transcriptional Repression

(2011) Sanjeevkumar R. Patel et al.   MOLECULAR CELL

Pancreatic β Cells Require NeuroD to Achieve and Maintain Functional Maturity

(2010) Chunyan Gu et al.   Cell Metabolism

The FoxA factors in organogenesis and differentiation

(2010) Klaus H Kaestner   CURRENT OPINION IN GENETICS & DEVELOPMENT

Dynamic expression ofgroucho-related genesGrg1andGrg3in foregut endoderm and antagonism of differentiation

(2010) Pilar Santisteban et al.   DEVELOPMENTAL DYNAMICS

Foxa1 and Foxa2 Maintain the Metabolic and Secretory Features of the Mature β-Cell

(2010) Nan Gao et al.   MOLECULAR ENDOCRINOLOGY

Expression of Groucho/TLE proteins during pancreas development

(2008) Brad G Hoffman et al.   BMC DEVELOPMENTAL BIOLOGY

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

(2008) N. Gao et al.   GENES & DEVELOPMENT

Histone deacetylase-related protein inhibits AES-mediated neuronal cell death by direct interaction

(2008) Xiaoguang Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Groucho/TLE/Grg family of transcriptional co-repressors

(2008) Barbara H Jennings et al.   GENOME BIOLOGY