Human heat shock cognate protein (HSC70/HSPA8) interacts with negatively charged phospholipids by a different mechanism than other HSP70s and brings HSP90 into membranes

First genome sequencing of SARS‐CoV‐2 recovered from an infected cat and its owner in Latin America

(2021) Renata Santiago Alberto Carlos et al.   Transboundary and Emerging Diseases

Membrane-Associated Heat Shock Proteins in Oncology: From Basic Research to New Theranostic Targets

(2020) Maxim Shevtsov et al.   Cells

Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domain

(2020) Paulo Roberto Dores-Silva et al.   CELL STRESS & CHAPERONES

Heat shock proteins and the biogenesis of cellular membranes

(2020) Antonio De Maio et al.   CELL STRESS & CHAPERONES

Targeted Natural Killer Cell–Based Adoptive Immunotherapy for the Treatment of Patients with NSCLC after Radiochemotherapy: A Randomized Phase II Clinical Trial

(2020) Gabriele Multhoff et al.   CLINICAL CANCER RESEARCH

Hsp70 interactions with membrane lipids regulate cellular functions in health and disease

(2019) Zsolt Balogi et al.   PROGRESS IN LIPID RESEARCH

Thermodynamic analysis of interactions of the Hsp90 with adenosine nucleotides: A comparative perspective

(2019) Karine Minari et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Thermal aggregates of human mortalin and Hsp70-1A behave as supramolecular assemblies

(2019) Vanessa T.R. Kiraly et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Interaction of Hsp90 with phospholipid model membranes

(2018) Muhan Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular AFM imaging of Hsp70-1A association with dipalmitoyl phosphatidylserine reveals membrane blebbing in the presence of cholesterol

(2018) Constanze Lamprecht et al.   CELL STRESS & CHAPERONES

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells

(2018) Hin Chu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Handling of Protein Aggregates by Disaggregation Machines

(2018) Axel Mogk et al.   MOLECULAR CELL

Hsp90 Mediates Membrane Deformation and Exosome Release

(2018) Elsa Lauwers et al.   MOLECULAR CELL

Binding of Pneumocystis carinii to the lung epithelial cell receptor HSPA5 (GRP78)

(2018) Theodore J. Kottom et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Pathways of cellular proteostasis in aging and disease

(2017) Courtney L. Klaips et al.   JOURNAL OF CELL BIOLOGY

Bacterial Hsp70 (DnaK) and mammalian Hsp70 interact differently with lipid membranes

(2016) Victor Lopez et al.   CELL STRESS & CHAPERONES

Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy

(2016) Kateryna Morozova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Surface heat shock protein 90 serves as a potential receptor for calcium oxalate crystal on apical membrane of renal tubular epithelial cells

(2016) Kedsarin Fong-ngern et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide Aptamer

(2015) Jessica Gobbo et al.   JNCI-Journal of the National Cancer Institute

Human Mitochondrial Hsp70 (Mortalin): Shedding Light on ATPase Activity, Interaction with Adenosine Nucleotides, Solution Structure and Domain Organization

(2015) Paulo R. Dores-Silva et al.   PLoS One

Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide Aptamer

(2015) Jessica Gobbo et al.   JNCI-Journal of the National Cancer Institute

Monitoring Charge Flux to Quantify Unusual Ligand-Induced Ion Channel Activity for Use in Biological Nanopore-Based Sensors

(2014) Florika C. Macazo et al.   ANALYTICAL CHEMISTRY

Extracellular cell stress proteins as biomarkers of human disease

(2014) A. Graham Pockley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Human heat shock protein 70 (Hsp70) as a peripheral membrane protein

(2014) Ajay K. Mahalka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Plasma membranes as heat stress sensors: From lipid-controlled molecular switches to therapeutic applications

(2014) Zsolt Török et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Interaction of heat shock protein 70 with membranes depends on the lipid environment

(2014) Gabrielle Armijo et al.   CELL STRESS & CHAPERONES

Hsp70 Translocates into the Plasma Membrane after Stress and Is Released into the Extracellular Environment in a Membrane-Associated Form that Activates Macrophages

(2014) V. L. Vega et al.   JOURNAL OF IMMUNOLOGY

Key role of lipids in heat stress management

(2013) Gábor Balogh et al.   FEBS LETTERS

Low resolution structural characterization of the Hsp70-interacting protein – Hip – from Leishmania braziliensis emphasizes its high asymmetry

(2012) P.R. Dores-Silva et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

The Molecular Chaperone Hsp70 Family Members Function by a Bidirectional Heterotrophic Allosteric Mechanism

(2011) Kelly P. da Silva et al.   PROTEIN AND PEPTIDE LETTERS

Distinguishing integral and receptor-bound heat shock protein 70 (Hsp70) on the cell surface by Hsp70-specific antibodies

(2010) Gabriele Multhoff et al.   CELL STRESS & CHAPERONES

Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: A form of communication during injury, infection, and cell damage

(2010) Antonio De Maio   CELL STRESS & CHAPERONES

The critical role of GRP78 in physiologic and pathologic stress

(2010) Kyle T Pfaffenbach et al.   CURRENT OPINION IN CELL BIOLOGY

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

(2010) Thomas Kirkegaard et al.   NATURE

A new feature of the stress response: increase in endocytosis mediated by Hsp70

(2009) Virginia L. Vega et al.   CELL STRESS & CHAPERONES

Monoclonal antibody to novel cell surface epitope on Hsc70 promotes morphogenesis of bile ducts in newborn rat liver

(2009) David R. Mills et al.   CELL STRESS & CHAPERONES

Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells

(2009) Daniela Schilling et al.   FASEB JOURNAL

Molecular Chaperone BiP Interacts with Borna Disease Virus Glycoprotein at the Cell Surface

(2009) T. Honda et al.   JOURNAL OF VIROLOGY

Membrane-associated stress proteins: More than simply chaperones

(2008) Ibolya Horváth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS