Expression of the SARS-CoV-2 receptorACE2 in human heart is associated with uncontrolled diabetes, obesity, and activation of the renin angiotensin system

Sodium–glucose cotransporter 2 inhibitor Dapagliflozin attenuates diabetic cardiomyopathy

(2020) M. Arow et al.   Cardiovascular Diabetology

Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

(2020) Yanan Cao et al.   Cell Discovery

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Obesity a Risk Factor for Severe COVID-19 Infection: Multiple Potential Mechanisms

(2020) Naveed Sattar et al.   CIRCULATION

Outcomes in Patients With Hyperglycemia Affected by Covid-19: Can We Do More on Glycemic Control?

(2020) Celestino Sardu et al.   DIABETES CARE

SARS-CoV-2 receptor ACE2 expression in the human heart: cause of a post-pandemic wave of heart failure?

(2020) Thomas Thum   EUROPEAN HEART JOURNAL

Characteristics and outcomes of patients hospitalized for COVID-19 and cardiac disease in Northern Italy

(2020) Riccardo M Inciardi et al.   EUROPEAN HEART JOURNAL

ACE2, COVID-19, and ACE Inhibitor and ARB Use during the Pandemic: The Pediatric Perspective

(2020) Andrew M. South et al.   HYPERTENSION

Effects Of ARBs And ACEIs On Virus Infection, Inflammatory Status And Clinical Outcomes In COVID-19 Patients With Hypertension: A Single Center Retrospective Study

(2020) Guang Yang et al.   HYPERTENSION

ACE2, COVID19 and serum ACE as a possible biomarker to predict severity of disease

(2020) Espen Skarstein Kolberg   JOURNAL OF CLINICAL VIROLOGY

Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19

(2020) Hao Cheng et al.   JOURNAL OF MEDICAL VIROLOGY

Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19

(2020) Giuseppe Mancia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19

(2020) Mandeep R. Mehra et al.   NEW ENGLAND JOURNAL OF MEDICINE

COVID-19 and the male susceptibility: the role of ACE2, TMPRSS2 and the androgen receptor

(2020) Georges Mjaess et al.   PROGRES EN UROLOGIE

COVID-19 Infection and Circulating ACE2 Levels: Protective Role in Women and Children

(2020) Elena Ciaglia et al.   Frontiers in Pediatrics

Challenging Issues in the Management of Cardiovascular Risk Factors in Diabetes During the COVID-19 Pandemic: A Review of Current Literature

(2020) Leili Rahimi et al.   ADVANCES IN THERAPY

Issues for the management of people with diabetes and COVID-19 in ICU

(2020) Antonio Ceriello et al.   Cardiovascular Diabetology

Single-cell analysis of SARS-CoV-2 receptor ACE2 and spike protein priming expression of proteases in the human heart

(2020) Hanning Liu et al.   CARDIOVASCULAR RESEARCH

Increased Hepatic ACE2 Expression in NAFL and Diabetes—A Risk for COVID-19 Patients?

(2020) Jelena Soldo et al.   DIABETES CARE

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people

(2020) Julia Hippisley-Cox et al.   HEART

SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications

(2020) Sonja Groß et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac injury is associated with severe outcome and death in patients with Coronavirus disease 2019 (COVID-19) infection: A systematic review and meta-analysis of observational studies

(2020) Mohammad Parohan et al.   European Heart Journal-Acute Cardiovascular Care

ACE2, Metformin, and COVID-19

(2020) Atul Malhotra et al.   iScience

Sodium‐glucose co‐transporter‐2 inhibitors and susceptibility to COVID ‐19: A population‐based retrospective cohort study

(2020) Christopher Sainsbury et al.   DIABETES OBESITY & METABOLISM

Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation

(2020) Lars Wallentin et al.   EUROPEAN HEART JOURNAL

Plasma ACE2 and risk of death or cardiometabolic diseases: a case-cohort analysis

(2020) Sukrit Narula et al.   LANCET

AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension

(2018) Jiao Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Durability of protective effect of dulaglutide on pancreatic β-cells in diabetic mice: GLP-1 receptor expression is not reduced despite long-term dulaglutide exposure

(2018) T. Kimura et al.   DIABETES & METABOLISM

Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving ‘SIRT1 and PGC-1α’

(2018) Maayan Waldman et al.   Cardiovascular Diabetology

Angiotensin-converting enzyme 2-Angiotensin 1-7/1-9 system: novel promising targets for heart failure treatment

(2017) Naim Kittana   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Roles of Angiotensin Peptides and Recombinant Human ACE2 in Heart Failure

(2017) Ratnadeep Basu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Circulating ACE2 activity correlates with cardiovascular disease development

(2016) K. Uri et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Preservation of Glucagon-Like Peptide-1 Level Attenuates Angiotensin II-Induced Tissue Fibrosis by Altering AT1/AT2 Receptor Expression and Angiotensin-Converting Enzyme 2 Activity in Rat Heart

(2015) Li-Hui Zhang et al.   CARDIOVASCULAR DRUGS AND THERAPY

Activation of the GLP-1 Receptor by Liraglutide Increases ACE2 Expression, Reversing Right Ventricle Hypertrophy, and Improving the Production of SP-A and SP-B in the Lungs of Type 1 Diabetes Rats

(2015) Marina Romaní-Pérez et al.   ENDOCRINOLOGY

ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis

(2013) AC Simões e Silva et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice

(2013) Bart JM Eskens et al.   Cardiovascular Diabetology

TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein

(2013) A. Heurich et al.   JOURNAL OF VIROLOGY

Circulating ACE2 activity is increased in patients with type 1 diabetes and vascular complications

(2011) Aino Soro-Paavonen et al.   JOURNAL OF HYPERTENSION

Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor

(2008) Rebecca A. Lew et al.   EXPERIMENTAL PHYSIOLOGY

Detection of Soluble Angiotensin-Converting Enzyme 2 in Heart Failure

(2008) Slava Epelman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY