ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis

The Physiology of Leukocyte Recruitment: An In Vivo Perspective

(2014) B. Petri et al.   JOURNAL OF IMMUNOLOGY

Angiotensin-(1–7) attenuates hypertension in exercise-trained renal hypertensive rats

(2012) Amin Shah et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways

(2012) Ahmed Z El-Hashim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia

(2012) Teng Jiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Angiotensin-(1–7) in kidney disease: a review of the controversies

(2012) Danielle Zimmerman et al.   CLINICAL SCIENCE

Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

(2012) Luciano S.A. Capettini et al.   CURRENT PHARMACEUTICAL DESIGN

Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking

(2012) Maria-Jesus Sanz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cardioprotective Effects of Telmisartan against Heart Failure in Rats Induced By Experimental Autoimmune Myocarditis through the Modulation of Angiotensin-Converting Enzyme-2/Angiotensin 1-7/Mas Receptor Axis

(2012) Vijayakumar Sukumaran et al.   International Journal of Biological Sciences

Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy

(2012) Zhen Liu et al.   LABORATORY INVESTIGATION

ACE2 Deficiency Enhances Angiotensin II-Mediated Aortic Profilin-1 Expression, Inflammation and Peroxynitrite Production

(2012) Hai-Yan Jin et al.   PLoS One

Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart

(2012) Elisandra Gava et al.   REGULATORY PEPTIDES

Counteraction between angiotensin II and angiotensin-(1–7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells

(2012) Hong Xue et al.   REGULATORY PEPTIDES

The Renoprotective Actions of Peroxisome Proliferator-Activated Receptors Agonists in Diabetes

(2012) M. C. Thomas et al.   PPAR Research

Renoprotective Effects of AVE0991, a Nonpeptide Mas Receptor Agonist, in Experimental Acute Renal Injury

(2012) Lívia Corrêa Barroso et al.   International Journal of Hypertension

Beneficial Effects of Long-Term Administration of an Oral Formulation of Angiotensin-(1–7) in Infarcted Rats

(2012) Fúlvia D. Marques et al.   International Journal of Hypertension

Angiotensin-(1–7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1

(2011) LaTronya T. McCollum et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chronic Exercise Preserves Renal Structure and Hemodynamics in Spontaneously Hypertensive Rats

(2011) Deepmala Agarwal et al.   ANTIOXIDANTS & REDOX SIGNALING

ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension

(2011) Srinivas Sriramula et al.   CARDIOVASCULAR RESEARCH

Contributions of ACE and mast cell chymase to endogenous angiotensin II generation and leucocyte recruitment in vivo

(2011) Chantal Company et al.   CARDIOVASCULAR RESEARCH

End-Organ Protection in Patients with Hypertension

(2011) Giuliano Tocci et al.   DRUGS

Angiotensin signalling in pulmonary fibrosis

(2011) Bruce D. Uhal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Angiotensin-(1-7) decreases LPS-induced inflammatory response in macrophages

(2011) Laura L. Souza et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Renal protection with angiotensin receptor blockers: where do we stand

(2011) Roland E. Schmieder et al.   JOURNAL OF NEPHROLOGY

Telmisartan acts through the modulation of ACE-2/ANG 1–7/mas receptor in rats with dilated cardiomyopathy induced by experimental autoimmune myocarditis

(2011) Vijayakumar Sukumaran et al.   LIFE SCIENCES

The renin–angiotensin–aldosterone system in 2011: role in hypertension and chronic kidney disease

(2011) Ana Cristina Simões e Silva et al.   PEDIATRIC NEPHROLOGY

Sensing sterile injury: Opportunities for pharmacological control

(2011) Gustavo B. Menezes et al.   PHARMACOLOGY & THERAPEUTICS

Emerging mechanisms of neutrophil recruitment across endothelium

(2011) Marcie R. Williams et al.   TRENDS IN IMMUNOLOGY

The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension

(2010) Vinayak Shenoy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Renin-angiotensin-aldosterone system blockade for cardiovascular diseases: current status

(2010) Terry KW Ma et al.   BRITISH JOURNAL OF PHARMACOLOGY

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

(2010) JiuChang Zhong et al.   CIRCULATION

Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

(2010) Merlin C. Thomas et al.   CIRCULATION RESEARCH

ACE2–angiotensin-(1–7)–Mas axis in renal ischaemia/reperfusion injury in rats

(2010) Kátia D. da Silveira et al.   CLINICAL SCIENCE

Angiotensin-(1–7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy

(2010) Elena Velkoska et al.   CLINICAL SCIENCE

ACE2: more of Ang-(1–7) or less Ang II?

(2010) Carlos M Ferrario   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases

(2010) Anderson J. Ferreira et al.   EXPERIMENTAL PHYSIOLOGY

Lifetime Overproduction of Circulating Angiotensin-(1-7) Attenuates Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Dysfunction and Remodeling

(2010) Nívia M. Santiago et al.   HYPERTENSION

Anti-Inflammatory Effects of the Activation of the Angiotensin-(1-7) Receptor, Mas, in Experimental Models of Arthritis

(2010) K. D. da Silveira et al.   JOURNAL OF IMMUNOLOGY

Atherosclerosis in chronic kidney disease: the role of macrophages

(2010) Valentina Kon et al.   Nature Reviews Nephrology

Increased ACE and Decreased ACE2 Expression in Kidneys from Patients with IgA Nephropathy

(2010) Sonoo Mizuiri et al.   NEPHRON CLINICAL PRACTICE

Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent

(2010) Jun Liu et al.   Biology of Sex Differences

Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension

(2009) Anderson J. Ferreira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chronic angiotensin-(1–7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits

(2009) Wutao Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of integrin-mediated TGFβ activation in the pathogenesis of pulmonary fibrosis

(2009) Amanda Goodwin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Anti-Inflammatory Effects of Angiotensin Receptor Blockers in the Brain and the Periphery

(2009) Julius Benicky et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction

(2009) Zamaneh Kassiri et al.   Circulation-Heart Failure

Angiotensin-(1–7), an alternative metabolite of the renin–angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat

(2009) John S. Lubel et al.   CLINICAL SCIENCE

Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

(2009) G. Y. Oudit et al.   DIABETES

Prevention of Pulmonary Hypertension by Angiotensin-Converting Enzyme 2 Gene Transfer

(2009) Yoriko Yamazato et al.   HYPERTENSION

Angiotensin (1−7) prevent heart dysfunction and left ventricular remodeling caused by renal dysfunction in 5/6 nephrectomy mice

(2009) Yiwen Li et al.   HYPERTENSION RESEARCH

Genetic deletion of the angiotensin-(1–7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria

(2009) Sérgio V.B. Pinheiro et al.   KIDNEY INTERNATIONAL

Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells

(2009) E. Gava et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

17β-Estradiol modulates local cardiac renin-angiotensin system to prevent cardiac remodeling in the DOCA-salt model of hypertension in rats

(2009) V. Shenoy et al.   PEPTIDES

Angiotensin-(1–7) and the G Protein-Coupled Receptor Mas Are Key Players in Renal Inflammation

(2009) Vanesa Esteban et al.   PLoS One

Relationship between angiotensin-(1-7) and angiotensin II correlates with hemodynamic changes in human liver cirrhosis

(2009) Walkíria Wingester Vilas-Boas et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis

(2008) Xiaopeng Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart

(2008) Chantal Mercure et al.   CIRCULATION RESEARCH

Role of angiotensin-converting enzyme 2 and angiotensin(1-7) in 17β-oestradiol regulation of renal pathology in renal wrap hypertension in rats

(2008) Hong Ji et al.   EXPERIMENTAL PHYSIOLOGY

Cardiac Overexpression of Angiotensin Converting Enzyme 2 Protects the Heart From Ischemia-Induced Pathophysiology

(2008) Shant Der Sarkissian et al.   HYPERTENSION

Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents

(2008) José A. Hernández Prada et al.   HYPERTENSION

Candesartan Ameliorates Cardiac Dysfunction Observed in Angiotensin-Converting Enzyme 2-Deficient Mice

(2008) Kazuto Nakamura et al.   HYPERTENSION RESEARCH

Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1–7)3292 rats

(2008) Ana Paula Nadu et al.   Journal of the American Society of Hypertension

ACE2 Overexpression Inhibits Angiotensin II-induced Monocyte Chemoattractant Protein-1 Expression in Macrophages

(2007) Yong-Jun Guo et al.   ARCHIVES OF MEDICAL RESEARCH