Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy
出版年份 2021 全文链接
标题
Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy
作者
关键词
AR negative autoregulation, AR-V translation, AR-V mRNA stability, AR-V protein stability, Castration-resistant prostate cancer, Castration resistance
出版物
CANCER LETTERS
Volume 504, Issue -, Pages 37-48
出版商
Elsevier BV
发表日期
2021-02-07
DOI
10.1016/j.canlet.2020.12.037
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer
- (2020) Yingming Li et al. CLINICAL CANCER RESEARCH
- ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
- (2019) Laura Cato et al. CANCER CELL
- SF3B2-mediated RNA splicing drives human prostate cancer progression
- (2019) Norihiko Kawamura et al. CANCER RESEARCH
- Recruitment of miR-8080 by luteolin inhibits androgen receptor splice variant 7 expression in castration-resistant prostate cancer
- (2019) Aya Naiki-Ito et al. CARCINOGENESIS
- Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases
- (2018) Heini M. L. Kallio et al. BRITISH JOURNAL OF CANCER
- Histone demethylase JMJD1A promotes alternative splicing of AR variant 7 (AR-V7) in prostate cancer cells
- (2018) Lingling Fan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer
- (2018) Adam Sharp et al. JOURNAL OF CLINICAL INVESTIGATION
- An oral androgen receptor PROTAC degrader for prostate cancer.
- (2017) Taavi K Neklesa et al. JOURNAL OF CLINICAL ONCOLOGY
- AR-V7 Transcripts in Whole Blood RNA of Patients with Metastatic Castration Resistant Prostate Cancer Correlate with Response to Abiraterone Acetate
- (2017) Tilman Todenhöfer et al. JOURNAL OF UROLOGY
- Emerging data on androgen receptor splice variants in prostate cancer
- (2016) Subing Cao et al. ENDOCRINE-RELATED CANCER
- Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer
- (2016) Jonathan Welti et al. EUROPEAN UROLOGY
- Interplay between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediates Castration Resistance
- (2016) Yang Zhan et al. MOLECULAR CANCER RESEARCH
- Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
- (2016) Himisha Beltran et al. NATURE MEDICINE
- Regulation of androgen receptor splice variant AR3 by PCGEM1
- (2016) Ziqiang Zhang et al. Oncotarget
- Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer
- (2016) Howard I. Scher et al. JAMA Oncology
- Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes
- (2015) D. Xu et al. CANCER RESEARCH
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
- NF- B2/p52:c-Myc:hnRNPA1 Pathway Regulates Expression of Androgen Receptor Splice Variants and Enzalutamide Sensitivity in Prostate Cancer
- (2015) N. Nadiminty et al. MOLECULAR CANCER THERAPEUTICS
- RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
- (2015) D. T. Miyamoto et al. SCIENCE
- The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7
- (2015) Jacqueline Stockley et al. Scientific Reports
- Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy
- (2015) Bo Cao et al. Oncotarget
- Rapid Induction of Androgen Receptor Splice Variants by Androgen Deprivation in Prostate Cancer
- (2014) Z. Yu et al. CLINICAL CANCER RESEARCH
- Androgen receptor and its splice variant, AR-V7, differentially regulate FOXA1 sensitive genes in LNCaP prostate cancer cells
- (2014) William C. Krause et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Androgen Receptor as a Driver of Therapeutic Resistance in Advanced Prostate Cancer
- (2014) Barbara Kahn et al. International Journal of Biological Sciences
- AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer
- (2014) Emmanuel S. Antonarakis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Castration-resistant prostate cancer: Adaptive responses in the androgen axis
- (2013) Alison Egan et al. CANCER TREATMENT REVIEWS
- Mechanisms of the androgen receptor splicing in prostate cancer cells
- (2013) L L Liu et al. ONCOGENE
- TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer
- (2013) M. D. Nyquist et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
- (2011) Changmeng Cai et al. CANCER CELL
- Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
- (2011) Elahe A. Mostaghel et al. CLINICAL CANCER RESEARCH
- Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival
- (2011) Emma Hörnberg et al. PLoS One
- A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
- (2011) Rong Hu et al. PROSTATE
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
- (2010) P. A. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
- (2009) Z. Guo et al. CANCER RESEARCH
- Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance
- (2008) S. M. Dehm et al. CANCER RESEARCH
- Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
- (2008) R. Hu et al. CANCER RESEARCH
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