Long noncoding RNA: A resident staff of genomic instability regulation in tumorigenesis

BRCA1 mutations in cancer: coordinating deficiencies in homologous recombination with tumorigenesis

(2020) John J. Krais et al.   CANCER RESEARCH

Pervasive chromosomal instability and karyotype order in tumour evolution

(2020) Thomas B. K. Watkins et al.   NATURE

Combined Antitumor Effects of Sorafenib and GPC3-CAR T Cells in Mouse Models of Hepatocellular Carcinoma

(2019) Xiuqi Wu et al.   MOLECULAR THERAPY

Non-coding RNAs and chromatin domains

(2019) Tatsuro Yamamoto et al.   CURRENT OPINION IN CELL BIOLOGY

The role of telomeres and telomerase in cirrhosis and liver cancer

(2019) Jean-Charles Nault et al.   Nature Reviews Gastroenterology & Hepatology

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks

(2019) Judit Domingo-Prim et al.   Nature Communications

Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells

(2019) Darawalee Wangsa et al.   NEOPLASIA

Structural biology of telomeres and telomerase

(2019) Eric M. Smith et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Telomere length alterations in microsatellite stable colorectal cancer and association with the immune response

(2018) Adriana Lopez-Doriga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Telomere Length and Lung Cancer Mortality among Heavy Smokers

(2018) Jennifer A. Doherty et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

LINP1 facilitates DNA damage repair through non-homologous end joining (NHEJ) pathway and subsequently decreases the sensitivity of cervical cancer cells to ionizing radiation

(2018) Xuanxuan Wang et al.   CELL CYCLE

Chromosome Segregation Is Biased by Kinetochore Size

(2018) Danica Drpic et al.   CURRENT BIOLOGY

RAD50 germline mutations are associated with poor survival in BRCA1/2 -negative breast cancer patients

(2018) Cong Fan et al.   INTERNATIONAL JOURNAL OF CANCER

How cells ensure correct repair of DNA double-strand breaks

(2018) Joonyoung Her et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determinants and clinical implications of chromosomal instability in cancer

(2018) Laurent Sansregret et al.   Nature Reviews Clinical Oncology

Identification of Drivers of Aneuploidy in Breast Tumors

(2018) Katherine Pfister et al.   Cell Reports

Carcinogens and DNA damage

(2018) Jessica L. Barnes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Noncoding RNA Ginir functions as an oncogene by associating with centrosomal proteins

(2018) Suchismita Panda et al.   PLOS BIOLOGY

ROS and the DNA damage response in cancer

(2018) Upadhyayula Sai Srinivas et al.   Redox Biology

Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks

(2017) Flavia Michelini et al.   NATURE CELL BIOLOGY

LncRNA lnc-RI regulates homologous recombination repair of DNA double-strand breaks by stabilizing RAD51 mRNA as a competitive endogenous RNA

(2017) Liping Shen et al.   NUCLEIC ACIDS RESEARCH

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins

(2016) Sungyul Lee et al.   CELL

3D Chromosome Regulatory Landscape of Human Pluripotent Cells

(2016) Xiong Ji et al.   Cell Stem Cell

TAD disruption as oncogenic driver

(2016) Anne-Laure Valton et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer

(2016) Youyou Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Breaking TADs: How Alterations of Chromatin Domains Result in Disease

(2016) Darío G. Lupiáñez et al.   TRENDS IN GENETICS

Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer

(2016) Youyou Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The DNA resection protein CtIP promotes mammary tumorigenesis

(2016) Colleen R. Reczek et al.   Oncotarget

A BRCA1-interacting lncRNA regulates homologous recombination

(2015) V. Sharma et al.   EMBO REPORTS

Human telomerase: biogenesis, trafficking, recruitment, and activation

(2015) Jens C. Schmidt et al.   GENES & DEVELOPMENT

Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin

(2015) Wendy J. Cannan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

(2015) Leizhen Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Chromatin Structure by Long Noncoding RNA

(2015) Gudrun Böhmdorfer et al.   TRENDS IN CELL BIOLOGY

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma

(2015) R. J. H. Ryan et al.   Cancer Discovery

Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner

(2015) Rikke B. Holmgaard et al.   Cell Reports

Re-replication of a Centromere Induces Chromosomal Instability and Aneuploidy

(2015) Stacey L. Hanlon et al.   PLoS Genetics

PCAT-1 , a Long Noncoding RNA, Regulates BRCA2 and Controls Homologous Recombination in Cancer

(2014) John R. Prensner et al.   CANCER RESEARCH

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes

(2014) Jill M. Dowen et al.   CELL

Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus

(2014) Jian-Feng Xiang et al.   CELL RESEARCH

Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection

(2014) Nodar Makharashvili et al.   MOLECULAR CELL

Transcript-RNA-templated DNA recombination and repair

(2014) Havva Keskin et al.   NATURE

Aurora-B overexpression is correlated with aneuploidy and poor prognosis in non-small cell lung cancer

(2013) Masafumi Takeshita et al.   LUNG CANCER

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

(2013) Wenbo Li et al.   NATURE

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

(2013) Fan Lai et al.   NATURE

Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up

(2013) Julien Vignard et al.   RADIOTHERAPY AND ONCOLOGY

Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma

(2012) Z. Deng et al.   JOURNAL OF CELL SCIENCE

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Homologous recombination and its regulation

(2012) L. Krejci et al.   NUCLEIC ACIDS RESEARCH

TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends

(2012) Verena Pfeiffer et al.   PLoS Genetics

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Multiple Wnt/ß-Catenin Responsive Enhancers Align with the MYC Promoter through Long-Range Chromatin Loops

(2011) Gregory S. Yochum   PLoS One

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

(2009) Zhong Deng et al.   MOLECULAR CELL

A  -catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers

(2009) G. S. Yochum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

The Rat1p 5′ to 3′ Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae

(2008) Brian Luke et al.   MOLECULAR CELL

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS

Mitotic checkpoint defects in human cancers and their implications to chemotherapy

(2007) Xianghong Wang   Frontiers in Bioscience-Landmark