Targeting FAPα-expressing tumor-associated mesenchymal stromal cells inhibits triple-negative breast cancer pulmonary metastasis

Fibroblast activation protein-positive fibroblasts promote tumor progression through secretion of CCL2 and interleukin-6 in esophageal squamous cell carcinoma

(2019) Nobuhide Higashino et al.   LABORATORY INVESTIGATION

Triple negative breast cancer: Key role of Tumor-Associated Macrophages in regulating the activity of anti-PD-1/PD-L1 agents

(2018) Matteo Santoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Metastatic and triple-negative breast cancer: challenges and treatment options

(2018) Sumayah Al-Mahmood et al.   Drug Delivery and Translational Research

Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents

(2017) Minfeng Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRβ Aptamer

(2017) Simona Camorani et al.   Theranostics

FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling

(2016) Xuguang Yang et al.   CANCER RESEARCH

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

(2016) Yufang Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Tumour cell-derived exosomes endow mesenchymal stromal cells with tumour-promotion capabilities

(2016) L Y Lin et al.   ONCOGENE

TNFα-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2+ neutrophils

(2016) P F Yu et al.   ONCOGENE

Role of epithelial–mesenchymal transition markers in triple-negative breast cancer

(2015) Sai Yin Cheung et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells

(2015) A. Lo et al.   CANCER RESEARCH

Macrophage Migration Inhibitory Factor–CXCR4 Is the Dominant Chemotactic Axis in Human Mesenchymal Stem Cell Recruitment to Tumors

(2015) Sofia Lourenco et al.   JOURNAL OF IMMUNOLOGY

Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations

(2015) M.M. Koczorowska et al.   Molecular Oncology

Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages

(2015) Xiao-Hua Jia et al.   Oncotarget

Prognostic Value of Cancer Stem Cells Markers in Triple-Negative Breast Cancer

(2015) Francesca Collina et al.   Biomed Research International

MSC-Regulated MicroRNAs Converge on the Transcription Factor FOXP2 and Promote Breast Cancer Metastasis

(2014) Benjamin G. Cuiffo et al.   Cell Stem Cell

Matrix metalloproteinase-1-mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis

(2014) Ivy A. W. Ho et al.   FASEB JOURNAL

Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment

(2014) P. Chaturvedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of tumor immune escape in triple-negative breast cancers (TNBC) with and without mutated BRCA 1

(2013) Jörg B. Engel et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis

(2013) Pallavi Chaturvedi et al.   JOURNAL OF CLINICAL INVESTIGATION

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Clinicopathologic features, patterns of recurrence, and survival among women with triple-negative breast cancer in the National Comprehensive Cancer Network

(2012) Nancy U. Lin et al.   CANCER

CCR2-Dependent Recruitment of Macrophages by Tumor-Educated Mesenchymal Stromal Cells Promotes Tumor Development and Is Mimicked by TNFα

(2012) Guangwen Ren et al.   Cell Stem Cell

Targeting Carcinoma-Associated Fibroblasts Within the Tumor Stroma With a Fibroblast Activation Protein-Activated Prodrug

(2012) W. N. Brennen et al.   JNCI-Journal of the National Cancer Institute

Mesenchymal stem cells promote growth and angiogenesis of tumors in mice

(2012) W-H Huang et al.   ONCOGENE

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

(2011) Hyung-Ok Lee et al.   BMC CANCER

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

(2011) Charlotte Rolny et al.   CANCER CELL

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

(2011) Abigail F. Welford et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Bone Marrow-Derived MSCs Can Home to Orthotopic Breast Cancer Tumors and Promote Bone Metastasis

(2010) R. H. Goldstein et al.   CANCER RESEARCH

Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieu

(2010) Yanique Rattigan et al.   EXPERIMENTAL CELL RESEARCH

TNFα-exposed Bone Marrow-derived Mesenchymal Stem Cells Promote Locomotion of MDA-MB-231 Breast Cancer Cells through Transcriptional Activation of CXCR3 Ligand Chemokines

(2010) Soon Young Shin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow

(2009) Masoud Soleimani et al.   Nature Protocols

Embryonic Stem Cell Marker Expression Pattern in Human Mesenchymal Stem Cells Derived from Bone Marrow, Adipose Tissue, Heart and Dermis

(2009) Una Riekstina et al.   Stem Cell Reviews and Reports

Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer

(2008) Nancy U. Lin et al.   CANCER