Differential mode of cholesterol inclusion with 2‐hydroxypropyl‐cyclodextrins increases safety margin in treatment of Niemann‐Pick disease type C
出版年份 2021 全文链接
标题
Differential mode of cholesterol inclusion with 2‐hydroxypropyl‐cyclodextrins increases safety margin in treatment of Niemann‐Pick disease type C
作者
关键词
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出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2021-03-30
DOI
10.1111/bph.15464
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020
- (2020) Elliott Lilley et al. BRITISH JOURNAL OF PHARMACOLOGY
- The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
- (2020) Nathalie Percie du Sert et al. PLOS BIOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Expanded access with intravenous hydroxypropyl-β-cyclodextrin to treat children and young adults with Niemann-Pick disease type C1: a case report analysis
- (2019) Caroline Hastings et al. Orphanet Journal of Rare Diseases
- Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology
- (2018) Steve P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers
- (2018) Michael J Curtis et al. BRITISH JOURNAL OF PHARMACOLOGY
- Role of 6- O -α-maltosyl-β-cyclodextrin in lysosomal cholesterol deprivation in Npc1- deficient Chinese hamster ovary cells
- (2018) Yasuyo Okada et al. CARBOHYDRATE RESEARCH
- Predicting the Binding Mode of 2-Hydroxypropyl-β-cyclodextrin to Cholesterol by Means of the MD Simulation and the 3D-RISM-KH Theory
- (2018) Yuji Hayashino et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Cyclodextrins: Assessing the Impact of Cavity Size, Occupancy, and Substitutions on Cytotoxicity and Cholesterol Homeostasis
- (2018) Lajos Szente et al. MOLECULES
- Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice
- (2018) Hiroki Takeda et al. Scientific Reports
- Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial
- (2017) Daniel S Ory et al. LANCET
- Early experience with compassionate use of 2 hydroxypropyl-beta-cyclodextrin for Niemann–Pick type C disease: review of initial published cases
- (2017) Juan Eduardo Megías-Vericat et al. NEUROLOGICAL SCIENCES
- Cyclodextrins and Iatrogenic Hearing Loss: New Drugs with Significant Risk
- (2017) Mark A. Crumling et al. Frontiers in Cellular Neuroscience
- Predicting the binding free energy of the inclusion process of 2-hydroxypropyl-β-cyclodextrin and small molecules by means of the MM/3D-RISM method
- (2016) Masatake Sugita et al. JOURNAL OF PHYSICS-CONDENSED MATTER
- In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-Pick Type C disease
- (2016) Yuki Kondo et al. MOLECULAR GENETICS AND METABOLISM
- Efficacy and ototoxicity of different cyclodextrins in Niemann-Pick C disease
- (2016) Cristin D. Davidson et al. Annals of Clinical and Translational Neurology
- Spectroscopic studies and molecular modeling for understanding the interactions between cholesterol and cyclodextrins
- (2016) Delphine Castagne et al. JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
- Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases
- (2016) Tsuyoshi Shuto et al. Scientific Reports
- Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann–Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease
- (2015) Yuta Tanaka et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease
- (2015) Charles H. Vite et al. Science Translational Medicine
- HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C During Disease Modeling with iPS Cells
- (2015) Minami Soga et al. STEM CELLS
- Lung toxicity of hydroxypropyl-β-cyclodextrin infusion
- (2013) Yin-Hsiu Chien et al. MOLECULAR GENETICS AND METABOLISM
- Cyclodextrin mediates rapid changes in lipid balance inNpc1−/−mice without carrying cholesterol through the bloodstream
- (2012) Anna M. Taylor et al. JOURNAL OF LIPID RESEARCH
- Cyclodextrins as Functional Excipients: Methods to Enhance Complexation Efficiency
- (2012) Thorsteinn Loftsson et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effects of cyclodextrin in two patients with Niemann–Pick Type C disease
- (2012) Muneaki Matsuo et al. MOLECULAR GENETICS AND METABOLISM
- Hearing Loss and Hair Cell Death in Mice Given the Cholesterol-Chelating Agent Hydroxypropyl-β-Cyclodextrin
- (2012) Mark A. Crumling et al. PLoS One
- Sterol Transfer between Cyclodextrin and Membranes: Similar but Not Identical Mechanism to NPC2-Mediated Cholesterol Transfer
- (2011) Leslie A. McCauliff et al. BIOCHEMISTRY
- Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations
- (2011) Charina M. Ramirez et al. JOURNAL OF LIPID RESEARCH
- Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction
- (2011) Cesar A. López et al. PLoS Computational Biology
- Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches
- (2010) Anton I. Rosenbaum et al. JOURNAL OF NEUROCHEMISTRY
- Niemann-Pick disease type C
- (2010) Marie T Vanier Orphanet Journal of Rare Diseases
- Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells
- (2010) A. I. Rosenbaum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Involvement of Lipid Rafts of Rabbit Red Blood Cells in Morphological Changes Induced by Methylated β-Cyclodextrins
- (2009) Keiichi Motoyama et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol
- (2009) Hyock Joo Kwon et al. CELL
- Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid
- (2009) Benny Liu et al. JOURNAL OF LIPID RESEARCH
- Chronic Cyclodextrin Treatment of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol and Glycosphingolipid Storage and Disease Progression
- (2009) Cristin D. Davidson et al. PLoS One
- Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse
- (2009) B. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Study of the cholesterol extraction capacity of β-cyclodextrin and its derivatives, relationships with their effects on endothelial cell viability and on membrane models
- (2008) Delphine Castagne et al. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
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