Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)- and calmodulin-mediated mechanism

Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy

(2017) Mootaz M. Salman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Hypothermia for Increased Intracranial Pressure: Is It Dead?

(2016) Christos Lazaridis et al.   Current Neurology and Neuroscience Reports

Progress in AQP Research and New Developments in Therapeutic Approaches to Ischemic and Hemorrhagic Stroke

(2016) Lauren Previch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transarterial Regional Brain Hypothermia Inhibits Acute Aquaporin-4 Surge and Sequential Microvascular Events in Ischemia/Reperfusion Injury

(2016) Kota Kurisu et al.   NEUROSURGERY

Identification and Molecular Mechanisms of the Rapid Tonicity-induced Relocalization of the Aquaporin 4 Channel

(2015) Philip Kitchen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypothermia for Intracranial Hypertension after Traumatic Brain Injury

(2015) Peter J.D. Andrews et al.   NEW ENGLAND JOURNAL OF MEDICINE

TRPV4 activation at the physiological temperature is a critical determinant of neuronal excitability and behavior

(2015) Koji Shibasaki et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The central role of aquaporins in the pathophysiology of ischemic stroke

(2015) Jasmine Vella   Frontiers in Cellular Neuroscience

Swelling and Eicosanoid Metabolites Differentially Gate TRPV4 Channels in Retinal Neurons and Glia

(2014) D. A. Ryskamp et al.   JOURNAL OF NEUROSCIENCE

Effects of focal mild hypothermia on thrombin-induced brain edema formation and the expression of protease activated receptor-1, matrix metalloproteinase-9 and aquaporin 4 in rats

(2014) DAPENG GAO et al.   Molecular Medicine Reports

Aquaporins: important but elusive drug targets

(2014) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

An emerging consensus on aquaporin translocation as a regulatory mechanism

(2012) Alex C. Conner et al.   MOLECULAR MEMBRANE BIOLOGY

Molecular mechanisms of therapeutic hypothermia on neurological function in a swine model of cardiopulmonary resuscitation

(2012) Hong Zhao et al.   RESUSCITATION

An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes

(2011) V. Benfenati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Hypothermia for Brain Ischemia: Where Have We Come and Where Do We Go?

(2010) M. A. Yenari et al.   STROKE