Hispolon suppresses migration and invasion of human nasopharyngeal carcinoma cells by inhibiting the urokinase-plasminogen activator through modulation of the Akt signaling pathway

What if cell culture media do not mimicin vivoredox settings?

(2016) Ivan Spasojević   REDOX REPORT

The urokinase-type plasminogen activator (uPA) system as a biomarker and therapeutic target in human malignancies

(2015) Shih-Chi Su et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas

(2015) Shun-Fa Yang et al.   Oncotarget

Terminalia catappa attenuates urokinase-type plasminogen activator expression through Erk pathways in Hepatocellular carcinoma

(2014) Chao-Bin Yeh et al.   BMC Complementary and Alternative Medicine

Pterostilbene suppresses oral cancer cell invasion by inhibiting MMP-2 expression

(2014) Chiao-Wen Lin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Hispolon Decreases Melanin Production and Induces Apoptosis in Melanoma Cells through the Downregulation of Tyrosinase and Microphthalmia-Associated Transcription Factor (MITF) Expressions and the Activation of Caspase-3, -8 and -9

(2014) Yi-Shyan Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biological evaluation of Phellinus linteus-fermented broths as anti-inflammatory agents

(2014) Chun-Jung Lin et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages

(2014) Liang-Yo Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hispolon from Phellinus linteus possesses mediate caspases activation and induces human nasopharyngeal carcinomas cells apoptosis through ERK1/2, JNK1/2 and p38 MAPK pathway

(2014) Ming-Ju Hsieh et al.   PHYTOMEDICINE

Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer

(2014) Martin Illemann et al.   Cancer Medicine

Hispolon from Phellinus linteus Induces G0/G1 Cell Cycle Arrest and Apoptosis in NB4 Human Leukaemia Cells

(2013) Yi-Chuan Chen et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Selaginella tamariscina extract suppresses TPA-induced invasion and metastasis through inhibition of MMP-9 in human nasopharyngeal carcinoma HONE-1 cells

(2013) Chung-Han Hsin et al.   BMC Complementary and Alternative Medicine

Phase II randomised proof-of-concept study of the urokinase inhibitor upamostat (WX-671) in combination with gemcitabine compared with gemcitabine alone in patients with non-resectable, locally advanced pancreatic cancer

(2013) V Heinemann et al.   BRITISH JOURNAL OF CANCER

Semaphorin 5A Promotes Gastric Cancer Invasion/Metastasis via Urokinase-Type Plasminogen Activator/Phosphoinositide 3-Kinase/Protein Kinase B

(2013) Guoqing Pan et al.   DIGESTIVE DISEASES AND SCIENCES

Hispolon Induces Apoptosis through JNK1/2-Mediated Activation of a Caspase-8, -9, and -3-Dependent Pathway in Acute Myeloid Leukemia (AML) Cells and Inhibits AML Xenograft Tumor Growth in Vivo

(2013) Pei-Ching Hsiao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Antimetastatic Effects of Resveratrol on Hepatocellular Carcinoma through the Downregulation of a Metastasis-Associated Protease by SP-1 Modulation

(2013) Chao-Bin Yeh et al.   PLoS One

Matrix metalloproteinase-2 as a target for head and neck cancer therapy

(2012) Ming-Hsien Chien et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Hispolon Induces Apoptosis and Cell Cycle Arrest of Human Hepatocellular Carcinoma Hep3B Cells by Modulating ERK Phosphorylation

(2011) Guan-Jhong Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Proteolytic networks in cancer

(2011) Steven D. Mason et al.   TRENDS IN CELL BIOLOGY

Treatment outcomes for different subgroups of nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy

(2011) Sheng-Fa Su et al.   Chinese Journal of Cancer

Blueberry Phytochemicals Inhibit Growth and Metastatic Potential of MDA-MB-231 Breast Cancer Cells through Modulation of the Phosphatidylinositol 3-Kinase Pathway

(2010) Lynn S. Adams et al.   CANCER RESEARCH

Clinical Outcomes and Patterns of Failure After Intensity-Modulated Radiotherapy for Nasopharyngeal Carcinoma

(2010) Wai Tong Ng et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Hispolon Suppresses SK-Hep1 Human Hepatoma Cell Metastasis by Inhibiting Matrix Metalloproteinase-2/9 and Urokinase-Plasminogen Activator through the PI3K/Akt and ERK Signaling Pathways

(2010) Guan-Jhong Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Molecular interactions in cancer cell metastasis

(2009) Susan A. Brooks et al.   ACTA HISTOCHEMICA

Phosphatidylinositol 4,5-bisphosphate-specific AKT1 is oncogenic

(2009) Nadine Dannemann et al.   INTERNATIONAL JOURNAL OF CANCER

A Medicinal Mushroom: Phellinus Linteus

(2008) Tongbo Zhu et al.   CURRENT MEDICINAL CHEMISTRY

Hispolon induces apoptosis in human gastric cancer cells through a ROS-mediated mitochondrial pathway

(2008) Wei Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE