Matrix metalloproteinase-2 as a target for head and neck cancer therapy

EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression

(2012) Géraldine Lescaille et al.   BMC CANCER

EMMPRIN silencing inhibits proliferation and perineural invasion of human salivary adenoid cystic carcinoma cells in vitro and in vivo

(2012) Xinjie Yang et al.   CANCER BIOLOGY & THERAPY

Therapeutic Efficacy of Silibinin on Human Neuroblastoma Cells: Akt and NF-κB Expressions May Play an Important Role in Silibinin-Induced Response

(2012) Meysam Yousefi et al.   NEUROCHEMICAL RESEARCH

Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression

(2012) Shang-Jyh Kao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population

(2011) Ajay Kumar Chaudhary et al.   BIOMARKERS

The Crosstalk Between the Matrix Metalloprotease System and the Chemokine Network in Acute Myeloid Leukemia

(2011) K. J. Hatfield et al.   CURRENT MEDICINAL CHEMISTRY

Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel

(2011) Horng-Rong Chang et al.   MOLECULAR CARCINOGENESIS

Efficient Targeting of Head and Neck Squamous Cell Carcinoma by Systemic Administration of a Dual uPA and MMP-Activated Engineered Anthrax Toxin

(2011) Jeffrey M. Schafer et al.   PLoS One

Physiology and pathophysiology of matrix metalloproteases

(2010) T. Klein et al.   AMINO ACIDS

Immunoexpression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in the metastasis of squamous cell carcinoma of the human tongue

(2010) CX Zhou et al.   AUSTRALIAN DENTAL JOURNAL

Effects of Osthole on Migration and Invasion in Breast Cancer Cells

(2010) Dapeng YANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits

(2010) Dimitris Stellas et al.   BMC CELL BIOLOGY

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Transforming growth factor-β and the hallmarks of cancer

(2010) Maozhen Tian et al.   CELLULAR SIGNALLING

Role of Matrix Metalloproteinase-9 Dimers in Cell Migration

(2010) Antoine Dufour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Regulatory Mechanism of Extracellular Hsp90α on Matrix Metalloproteinase-2 Processing and Tumor Angiogenesis

(2010) Xiaomin Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oral and Maxillofacial Pathology: MMP and TIMP gene expression in head and neck squamous cell carcinomas and adjacent tissues

(2010) B Birkedal-Hansen et al.   ORAL DISEASES

Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: Contrasting, overlapping and compensatory functions

(2009) Elena I. Deryugina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structural and functional bases for allosteric control of MMP activities: Can it pave the path for selective inhibition?

(2009) Netta Sela-Passwell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix

(2009) A. D. Kandasamy et al.   CARDIOVASCULAR RESEARCH

In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer

(2009) Emilia S. Olson et al.   Integrative Biology

MMP-2 alters VEGF expression via αVβ3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells

(2009) Chandramu Chetty et al.   INTERNATIONAL JOURNAL OF CANCER

SecretedVersusMembrane-anchored Collagenases

(2009) Farideh Sabeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

(2009) Roopali Roy et al.   JOURNAL OF CLINICAL ONCOLOGY

Matrix Metalloproteinase 2-Integrin αvβ3 Binding Is Required for Mesenchymal Cell Invasive Activity but Not Epithelial Locomotion: A Computational Time-Lapse Study

(2008) Paul A. Rupp et al.   MOLECULAR BIOLOGY OF THE CELL

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE