Mild hyperthermia promotes immune checkpoint blockade-based immunotherapy against metastatic pancreatic cancer using size-adjustable nanoparticles

Targeting cancer-associated fibroblasts by dual-responsive lipid-albumin nanoparticles to enhance drug perfusion for pancreatic tumor therapy

(2020) Qianwen Yu et al.   JOURNAL OF CONTROLLED RELEASE

Direct treatment versus indirect: Thermo‐ablative and mild hyperthermia effects

(2020) Macy Payne et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

The Roles of CD8+ T Cell Subsets in Antitumor Immunity

(2020) Michael St. Paul et al.   TRENDS IN CELL BIOLOGY

PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer

(2020) Wendan Yu et al.   Cell Death & Disease

Biodegradable Poly(γ-glutamic acid)@glucose oxidase@carbon dot nanoparticles for simultaneous multimodal imaging and synergetic cancer therapy

(2020) Ming Zhang et al.   BIOMATERIALS

Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape

(2019) Xianjie Jiang et al.   Molecular Cancer

Inflammation and Pancreatic Cancer: Focus on Metabolism, Cytokines, and Immunity

(2019) Andrea Padoan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Size-adjustable micelles co-loaded with a chemotherapeutic agent and an autophagy inhibitor for enhancing cancer treatment via increased tumor retention

(2019) Jingdong Rao et al.   Acta Biomaterialia

Nanomedicine‐Based Immunotherapy for the Treatment of Cancer Metastasis

(2019) Pengcheng Zhang et al.   ADVANCED MATERIALS

Synergistic triple-combination therapy with hyaluronic acid-shelled PPy/CPT nanoparticles results in tumor regression and prevents tumor recurrence and metastasis in 4T1 breast cancer

(2019) Wei Sun et al.   BIOMATERIALS

Transcytosis of Nanomedicine for Tumor Penetration

(2019) Yan Liu et al.   NANO LETTERS

Self-Delivery Micellar Nanoparticles Prevent Premetastatic Niche Formation by Interfering with the Early Recruitment and Vascular Destruction of Granulocytic Myeloid-Derived Suppressor Cells

(2019) Yang Long et al.   NANO LETTERS

Chemotherapy-induced metastasis: mechanisms and translational opportunities

(2018) George S. Karagiannis et al.   CLINICAL & EXPERIMENTAL METASTASIS

Effective treatment of the primary tumor and lymph node metastasis by polymeric micelles with variable particle sizes

(2018) Ling Mei et al.   JOURNAL OF CONTROLLED RELEASE

PD-L1 knockdown via hybrid micelle promotes paclitaxel induced Cancer-Immunity Cycle for melanoma treatment

(2018) Xian Tang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Systemic treatment of pancreatic cancer revisited

(2018) Michel Ducreux et al.   SEMINARS IN ONCOLOGY

Overcoming the resistance of pancreatic cancer to immune checkpoint inhibitors

(2017) Richard A. Skelton et al.   JOURNAL OF SURGICAL ONCOLOGY

Complex effects of tumor microenvironment on the tumor disposition of carrier-mediated agents

(2017) Andrew T Lucas et al.   Nanomedicine

Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2

(2017) Krzysztof M. Zak et al.   STRUCTURE

Targeting Tumor-Associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors

(2016) Lei Miao et al.   CANCER RESEARCH

Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination

(2016) Celine Boutros et al.   Nature Reviews Clinical Oncology

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment

(2015) Jinqiang Wang et al.   ACS Nano

Perspectives in the treatment of pancreatic adenocarcinoma

(2015) Angel Cid-Arregui   WORLD JOURNAL OF GASTROENTEROLOGY

Thermosensitive liposomes for localized delivery and triggered release of chemotherapy

(2013) Terence Ta et al.   JOURNAL OF CONTROLLED RELEASE

Development of an Orthotopic Model of Invasive Pancreatic Cancer in an Immunocompetent Murine Host

(2010) W. W. Tseng et al.   CLINICAL CANCER RESEARCH

Pancreatic Cancer Cells Expressing Hypoxia-Inducible Factor-1α Tend to Be Adjacent to Intratumoral Blood Vessels

(2010) B.-Q. Cheng et al.   EUROPEAN SURGICAL RESEARCH

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Protein nanoparticles as drug carriers in clinical medicine

(2008) Michael J. Hawkins et al.   ADVANCED DRUG DELIVERY REVIEWS