Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets

ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response

(2020) Sankari Nagarajan et al.   NATURE GENETICS

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

(2020) Kiyomi Morita et al.   Nature Communications

NIPBL: a new player in myeloid cells differentiation

(2019) Mara Mazzola et al.   HAEMATOLOGICA

Late relapse in acute myeloid leukemia (AML): clonal evolution or therapy-related leukemia?

(2019) Musa Yilmaz et al.   Blood Cancer Journal

Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia

(2019) Nicole A. McNeer et al.   LEUKEMIA

Uncovering the genomic landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically normal FLT 3‐ ITD AML

(2019) Daelynn R. Buelow et al.   CTS-Clinical and Translational Science

Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness

(2019) Meaghan Boileau et al.   Nature Communications

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

(2019) Benjamin H. Durham et al.   NATURE MEDICINE

Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients

(2018) Philipp A. Greif et al.   CLINICAL CANCER RESEARCH

NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome

(2018) Ann-Kathrin Eisfeld et al.   LEUKEMIA

ASXL1 mutations in AML are associated with specific clinical and cytogenetic characteristics

(2018) Katerina Kakosaiou et al.   LEUKEMIA & LYMPHOMA

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML

(2018) Courtney D. DiNardo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

(2018) Xiaotu Ma et al.   NATURE

Roles of NIPBL in maintenance of genome stability

(2018) Danyan Gao et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

CSF1R inhibitors exhibit anti-tumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

(2018) David K. Edwards et al.   BLOOD

Functional genomic landscape of acute myeloid leukaemia

(2018) Jeffrey W. Tyner et al.   NATURE

Immune Escape of Relapsed AML Cells after Allogeneic Transplantation

(2018) Matthew J. Christopher et al.   NEW ENGLAND JOURNAL OF MEDICINE

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

(2017) Hamid Bolouri et al.   NATURE MEDICINE

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

(2017) Richard M. Stone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bone marrow stroma cells derived from mononuclear cells at diagnosis as a source of germline control DNA for determination of somatic mutations in acute myeloid leukemia

(2017) H Mujahed et al.   Blood Cancer Journal

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

(2016) Hartmut Döhner et al.   BLOOD

Evolution of acute myelogenous leukemia stem cell properties after treatment and progression

(2016) T.-C. Ho et al.   BLOOD

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Whole-exome sequencing reveals the spectrum of gene mutations and the clonal evolution patterns in paediatric acute myeloid leukaemia

(2016) Norio Shiba et al.   BRITISH JOURNAL OF HAEMATOLOGY

Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse

(2016) Jason E. Farrar et al.   CANCER RESEARCH

Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia

(2016) V Madan et al.   LEUKEMIA

Ordering of mutations in acute myeloid leukemia with partial tandem duplication of MLL (MLL-PTD)

(2016) Q-Y Sun et al.   LEUKEMIA

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

(2016) Sheng Li et al.   NATURE MEDICINE

Survival of Patients with Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Cell Transplantation: A Center for International Blood and Marrow Transplant Research Study

(2015) Nelli Bejanyan et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse

(2015) M. Garg et al.   BLOOD

PHF6mutations in paediatric acute myeloid leukaemia

(2015) Jasmijn D. E. de Rooij et al.   BRITISH JOURNAL OF HAEMATOLOGY

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

(2015) J. D. E. de Rooij et al.   HAEMATOLOGICA

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

(2015) J. D. E. de Rooij et al.   HAEMATOLOGICA

Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex

(2014) J. Dias et al.   GENES & DEVELOPMENT

Low frequency of H3.3 mutations and upregulated DAXX expression in MDS

(2013) Y. Attieh et al.   BLOOD

The landscape of somatic mutations in Down syndrome–related myeloid disorders

(2013) Kenichi Yoshida et al.   NATURE GENETICS

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

(2012) Tobias Rausch et al.   CELL

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value

(2011) M. Pratcorona et al.   HAEMATOLOGICA

The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity

(2011) Liza B. John et al.   MOLECULAR IMMUNOLOGY

Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations

(2010) W.-C. Chou et al.   BLOOD

Response-Guided Induction Therapy in Pediatric Acute Myeloid Leukemia With Excellent Remission Rate

(2010) Jonas Abrahamsson et al.   JOURNAL OF CLINICAL ONCOLOGY

Late relapses in acute myeloid leukemia: analysis of characteristics and outcome

(2010) Dushyant Verma et al.   LEUKEMIA & LYMPHOMA

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

(2010) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cohesin complex and its roles in chromosome biology

(2008) J.-M. Peters et al.   GENES & DEVELOPMENT

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

(2008) T. D. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA