Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis

Second primary malignancies in blastic plasmacytoid dendritic cell neoplasm: a national database study

(2020) Vignesh Ramachandran et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Chronic myelomonocytic leukaemia followed by blastic plasmacytoid dendritic cell neoplasm

(2019) Benjamin Lebecque et al.   BRITISH JOURNAL OF HAEMATOLOGY

Dual Expression of TCF4 and CD123 is Highly Sensitive and Specific For Blastic Plasmacytoid Dendritic Cell Neoplasm

(2019) Narittee Sukswai et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

(2019) Regine J. Dress et al.   NATURE IMMUNOLOGY

Whole‐genome analysis uncovers recurrent IKZF1 inactivation and aberrant cell adhesion in blastic plasmacytoid dendritic cell neoplasm

(2019) Armando N. Bastidas Torres et al.   GENES CHROMOSOMES & CANCER

Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm: association with immunoblastoid cytomorphology, MYC expression, and drug response

(2018) Kana Sakamoto et al.   LEUKEMIA

Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells

(2018) Patrick Fernandes Rodrigues et al.   NATURE IMMUNOLOGY

Genomic aberrations involving 12p/ETV6 are highly prevalent in blastic plasmacytoid dendritic cell neoplasms and might represent early clonal events

(2018) Zhenya Tang et al.   LEUKEMIA RESEARCH

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment

(2018) Matheus Dyczynski et al.   Cell Death & Disease

Biallelic inactivation of the retinoblastoma gene results in transformation of chronic myelomonocytic leukemia to a blastic plasmacytoid dendritic cell neoplasm: shared clonal origins of two aggressive neoplasms

(2018) Mrinal M. Patnaik et al.   Blood Cancer Journal

Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target

(2018) Maria Rosaria Sapienza et al.   HAEMATOLOGICA

NTRK fusion-positive cancers and TRK inhibitor therapy

(2018) Emiliano Cocco et al.   Nature Reviews Clinical Oncology

Bortezomib as a new therapeutic approach for blastic plasmacytoid dendritic cell neoplasm

(2017) Laure Philippe et al.   HAEMATOLOGICA

High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization

(2017) Marcela Alcántara-Hernández et al.   IMMUNITY

Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin

(2017) L Brunetti et al.   LEUKEMIA

Recurrent MYB rearrangement in blastic plasmacytoid dendritic cell neoplasm

(2017) K Suzuki et al.   LEUKEMIA

A distinct subset of plasmacytoid dendritic cells induces activation and differentiation of B and T lymphocytes

(2017) Hong Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the human DC lineage through the integration of high-dimensional techniques

(2017) Peter See et al.   SCIENCE

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish

(2017) J-W Lu et al.   Blood Cancer Journal

Breast cancer metastasis: Putative therapeutic role of vascular cell adhesion molecule-1

(2017) Rohit Sharma et al.   CELLULAR ONCOLOGY

Bortezomib as a new therapeutic approach for blastic plasmacytoid dendritic cell neoplasm

(2017) Laure Philippe et al.   HAEMATOLOGICA

Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

(2016) A. Emadali et al.   BLOOD

Blastic plasmacytoid dendritic cell neoplasm associated with chronic myelomonocytic leukemia

(2016) Z. Hu et al.   BLOOD

LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis

(2016) A. Ceroi et al.   BLOOD

A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm

(2016) Michele Ceribelli et al.   CANCER CELL

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity

(2016) Michaël Chopin et al.   Cell Reports

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

(2015) J. D. E. de Rooij et al.   HAEMATOLOGICA

Blastic plasmacytoid dendritic cell neoplasm following Waldenström macroglobulinemia

(2015) S. Milley et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

(2015) J. D. E. de Rooij et al.   HAEMATOLOGICA

Targeted ultra-deep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm

(2015) Albrecht Stenzinger et al.   Oncotarget

Vascular cell adhesion molecule-1 (VCAM-1)-An increasing insight into its role in tumorigenicity and metastasis

(2014) Martin Schlesinger et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition

(2014) M R Sapienza et al.   LEUKEMIA

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

(2014) Giulio Genovese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

(2014) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

TET2mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow

(2013) Khaled Alayed et al.   AMERICAN JOURNAL OF HEMATOLOGY

Blastic plasmacytoid dendritic cell neoplasm: clinical features in 90 patients

(2013) F. Julia et al.   BRITISH JOURNAL OF DERMATOLOGY

Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm

(2013) J Menezes et al.   LEUKEMIA

The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment

(2013) Elisa Laurenti et al.   NATURE IMMUNOLOGY

SPIB, a novel immunohistochemical marker for human blastic plasmacytoid dendritic cell neoplasms: characterization of its expression in major hematolymphoid neoplasms

(2012) S. Montes-Moreno et al.   BLOOD

Homozygous deletions ofCDKN2Aare present in all dic(9;20)(p13·2;q11·2)-positive B-cell precursor acute lymphoblastic leukaemias and may be important for leukaemic transformation

(2012) Vasilios Zachariadis et al.   BRITISH JOURNAL OF HAEMATOLOGY

Sox4 functions as a positive regulator of β-catenin signaling through upregulation of TCF4 during morular differentiation of endometrial carcinomas

(2012) Makoto Saegusa et al.   LABORATORY INVESTIGATION

HOXA9 Methylation by PRMT5 Is Essential for Endothelial Cell Expression of Leukocyte Adhesion Molecules

(2012) S. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

(2011) G. Aue et al.   BLOOD

Twenty-one cases of blastic plasmacytoid dendritic cell neoplasm: focus on biallelic locus 9p21.3 deletion

(2011) M. Lucioni et al.   BLOOD

Continuous Expression of the Transcription Factor E2-2 Maintains the Cell Fate of Mature Plasmacytoid Dendritic Cells

(2010) Hiyaa S. Ghosh et al.   IMMUNITY

Extended diagnostic criteria for plasmacytoid dendritic cell leukaemia

(2009) Francine Garnache-Ottou et al.   BRITISH JOURNAL OF HAEMATOLOGY

CD2 Distinguishes Two Subsets of Human Plasmacytoid Dendritic Cells with Distinct Phenotype and Functions

(2009) T. Matsui et al.   JOURNAL OF IMMUNOLOGY

Recurrent genomic aberrations combined with deletions of various tumour suppressor genes may deregulate the G1/S transition in CD4+CD56+ haematodermic neoplasms and contribute to the aggressiveness of the disease

(2009) F Jardin et al.   LEUKEMIA

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

(2008) Babacar Cisse et al.   CELL

TCL1A expression delineates biological and clinical variability in B-cell lymphoma

(2008) Mohit Aggarwal et al.   MODERN PATHOLOGY

Identification of SOX4 target genes using phylogenetic footprinting-based prediction from expression microarrays suggests that overexpression of SOX4 potentiates metastasis in hepatocellular carcinoma

(2008) Y-L Liao et al.   ONCOGENE