Neuroprotective Benefits of Exercise and MitoQ on Memory Function, Mitochondrial Dynamics, Oxidative Stress, and Neuroinflammation in D-Galactose-Induced Aging Rats

The mitochondria‐targeted anti‐oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance

(2020) Liang Kang et al.   CELL PROLIFERATION

Ascorbic Acid Mitigates D-galactose-Induced Brain Aging by Increasing Hippocampal Neurogenesis and Improving Memory Function

(2019) Sung Nam et al.   Nutrients

Leptin in hippocampus mediates benefits of mild exercise by an antioxidant on neurogenesis and memory

(2019) Jang Soo Yook et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older AdultsNovelty and Significance

(2018) Matthew J. Rossman et al.   HYPERTENSION

Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice

(2018) Rachel A. Gioscia-Ryan et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Effect of MitoQ on Aging-Related Biomarkers: A Systematic Review and Meta-Analysis

(2018) Andrea J. Braakhuis et al.   Oxidative Medicine and Cellular Longevity

The mitochondrially targeted antioxidant MitoQ protects the intestinal barrier by ameliorating mitochondrial DNA damage via the Nrf2/ARE signaling pathway

(2018) Qiongyuan Hu et al.   Cell Death & Disease

Exercise training decreases NADPH oxidase activity and restores skeletal muscle mass in heart failure rats

(2017) Telma F. Cunha et al.   JOURNAL OF APPLIED PHYSIOLOGY

Microvascular Endothelial Dysfunction in Sedentary, Obese Humans Is Mediated by NADPH OxidaseHighlights

(2016) Justin D. La Favor et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial quality control pathways as determinants of metabolic health

(2015) Ntsiki M. Held et al.   BIOESSAYS

Exercise training protects against atherosclerotic risk factors through vascular NADPH oxidase, extracellular signal-regulated kinase 1/2 and stress-activated protein kinase/c-Jun N-terminal kinase downregulation in obese rats

(2015) Sabeur Touati et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

NADPH oxidase 2-dependent oxidative stress, mitochondrial damage and apoptosis in the ventral cochlear nucleus of d-galactose-induced aging rats

(2015) Z. Du et al.   NEUROSCIENCE

Exercise but not (–)-epigallocatechin-3-gallate or β-alanine enhances physical fitness, brain plasticity, and behavioral performance in mice

(2015) Tushar K. Bhattacharya et al.   PHYSIOLOGY & BEHAVIOR

Mutations causing mitochondrial disease: What is new and what challenges remain?

(2015) R. N. Lightowlers et al.   SCIENCE

Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of d-galactose treated mice

(2015) Pei-chun Chao et al.   Food & Function

Voluntary wheel running, but not a diet containing (−)-epigallocatechin-3-gallate and β-alanine, improves learning, memory and hippocampal neurogenesis in aged mice

(2014) Trisha E. Gibbons et al.   BEHAVIOURAL BRAIN RESEARCH

The role of Nox2-derived ROS in the development of cognitive impairment after sepsis

(2014) Marina S Hernandes et al.   Journal of Neuroinflammation

Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice

(2014) Rachel A. Gioscia-Ryan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Mitochondrial DNA: Impacting Central and Peripheral Nervous Systems

(2014) Valerio Carelli et al.   NEURON

Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease

(2013) A R Hall et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

(2013) Stephen L. Archer   NEW ENGLAND JOURNAL OF MEDICINE

The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease

(2012) María E. Solesio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inflamm-ageing

(2012) Elisa Cevenini et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) M. J. McManus et al.   JOURNAL OF NEUROSCIENCE

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

The role of caspases in Alzheimer’s disease; potential novel therapeutic opportunities

(2010) Troy T. Rohn   APOPTOSIS

Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: Prevention by the targeted antioxidant MitoQ

(2010) Aurélia Vergeade et al.   FREE RADICAL BIOLOGY AND MEDICINE

NOX activity in brain aging: Exacerbation by high fat diet

(2010) Annadora J. Bruce-Keller et al.   FREE RADICAL BIOLOGY AND MEDICINE

Treadmill training restores spatial cognitive deficits and neurochemical alterations in the hippocampus of rats submitted to an intracerebroventricular administration of streptozotocin

(2010) Letícia Rodrigues et al.   JOURNAL OF NEURAL TRANSMISSION

Expression of the apoptosis-related proteins caspase-3 and NF-κB in the hippocampus of Tg2576 mice

(2010) Yan-Li Niu et al.   Neuroscience Bulletin

Activated astroglia during chronic inflammation in Alzheimer's disease—Do they neglect their neurosupportive roles?

(2009) Stacey Fuller et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Impairments of astrocytes are involved in the d-galactose-induced brain aging

(2008) Ming Lei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS