Single Cell RNA-Seq and Machine Learning Reveal Novel Subpopulations in Low-Grade Inflammatory Monocytes With Unique Regulatory Circuits
出版年份 2021 全文链接
标题
Single Cell RNA-Seq and Machine Learning Reveal Novel Subpopulations in Low-Grade Inflammatory Monocytes With Unique Regulatory Circuits
作者
关键词
-
出版物
Frontiers in Immunology
Volume 12, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-02-23
DOI
10.3389/fimmu.2021.627036
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lactobacillus paracasei-derived extracellular vesicles attenuate the intestinal inflammatory response by augmenting the endoplasmic reticulum stress pathway
- (2020) Ji Hyun Choi et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Determining sequencing depth in a single-cell RNA-seq experiment
- (2020) Martin Jinye Zhang et al. Nature Communications
- Prediction of condition-specific regulatory genes using machine learning
- (2020) Qi Song et al. NUCLEIC ACIDS RESEARCH
- TICAM2-related pathway mediates neutrophil exhaustion
- (2020) RuiCi Lin et al. Scientific Reports
- Frontline Science: Monocytes sequentially rewire metabolism and bioenergetics during an acute inflammatory response
- (2019) Xuewei Zhu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis
- (2019) Shuo Geng et al. Science Advances
- The cis-Regulatory Atlas of the Mouse Immune System
- (2019) Hideyuki Yoshida et al. CELL
- A comparison of single-cell trajectory inference methods
- (2019) Wouter Saelens et al. NATURE BIOTECHNOLOGY
- Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells
- (2019) Cornelius Fischer et al. Science Signaling
- Single-Cell RNA-Seq Technologies and Related Computational Data Analysis
- (2019) Geng Chen et al. Frontiers in Genetics
- Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders
- (2019) Marina Spörrer et al. EBioMedicine
- HMMRATAC: a Hidden Markov ModeleR for ATAC-seq
- (2019) Evan D Tarbell et al. NUCLEIC ACIDS RESEARCH
- Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases
- (2019) Theodore S. Kapellos et al. Frontiers in Immunology
- Phenylbutyrate facilitates homeostasis of non-resolving inflammatory macrophages
- (2019) Allison Rahtes et al. Innate Immunity
- ShinyGO: a graphical gene-set enrichment tool for animals and plants
- (2019) Steven Xijin Ge et al. BIOINFORMATICS
- The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2
- (2018) Dimitry A. Chistiakov et al. IMMUNOBIOLOGY
- Using single‐cell genomics to understand developmental processes and cell fate decisions
- (2018) Jonathan A Griffiths et al. Molecular Systems Biology
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Points of Significance: Statistics versus machine learning
- (2018) Danilo Bzdok et al. NATURE METHODS
- Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry
- (2018) Anouk A.J. Hamers et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
- (2018) Ekaterini Platanitis et al. Frontiers in Immunology
- Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection
- (2017) Amanda J. Lee et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SCENIC: single-cell regulatory network inference and clustering
- (2017) Sara Aibar et al. NATURE METHODS
- HOCOMOCO: towards a complete collection of transcription factor binding models for human and mouse via large-scale ChIP-Seq analysis
- (2017) Ivan V Kulakovskiy et al. NUCLEIC ACIDS RESEARCH
- 4-PBA inhibits LPS-induced inflammation through regulating ER stress and autophagy in acute lung injury models
- (2017) Meichun Zeng et al. TOXICOLOGY LETTERS
- Beneficial Effects of Sodium Phenylbutyrate Administration during Infection with Salmonella enterica Serovar Typhimurium
- (2016) Stefan Jellbauer et al. INFECTION AND IMMUNITY
- TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target
- (2016) M. Obayed Ullah et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Low-grade inflammatory polarization of monocytes impairs wound healing
- (2016) Ruoxi Yuan et al. JOURNAL OF PATHOLOGY
- 4-Phenylbutyric Acid Attenuates Pancreatic Beta-Cell Injury in Rats with Experimental Severe Acute Pancreatitis
- (2016) Yu-pu Hong et al. International Journal of Endocrinology
- The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis
- (2016) Shuo Geng et al. Nature Communications
- The “Intermediate” CD14++CD16+ monocyte subset increases in severe peripheral artery disease in humans
- (2016) Moritz Wildgruber et al. Scientific Reports
- Molecular Mechanisms That Underlie the Dynamic Adaptation of Innate Monocyte Memory to Varying Stimulant Strength of TLR Ligands
- (2016) Ruoxi Yuan et al. Frontiers in Immunology
- Defining cell types and states with single-cell genomics
- (2015) Cole Trapnell GENOME RESEARCH
- The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis
- (2015) P.S. Kolb et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation
- (2015) Christine D. Palmer et al. JOURNAL OF IMMUNOLOGY
- Innate Immune Programing by Endotoxin and Its Pathological Consequences
- (2015) Matthew C. Morris et al. Frontiers in Immunology
- Building Predictive Models inRUsing thecaretPackage
- (2015) Max Kuhn Journal of Statistical Software
- Regularization Paths for Generalized Linear Models via Coordinate Descent
- (2015) Jerome Friedman et al. Journal of Statistical Software
- Dynamic Modulation of Innate Immune Response by Varying Dosages of Lipopolysaccharide (LPS) in Human Monocytic Cells
- (2014) Matthew C. Morris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular and Cellular Mechanisms Responsible for Cellular Stress and Low-grade Inflammation Induced by a Super-low Dose of Endotoxin
- (2014) Bianca Baker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional Control of Macrophage Polarization
- (2013) Derin Tugal et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Gene selection with guided regularized random forest
- (2013) Houtao Deng et al. PATTERN RECOGNITION
- Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway
- (2013) Hee Jung Kim et al. Scientific Reports
- The three human monocyte subsets: implications for health and disease
- (2012) Kok Loon Wong et al. IMMUNOLOGIC RESEARCH
- Molecular Mechanism Responsible for the Priming of Macrophage Activation
- (2012) Hui Deng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Mechanisms Responsible for the Selective and Low-Grade Induction of Proinflammatory Mediators in Murine Macrophages by Lipopolysaccharide
- (2012) U. Maitra et al. JOURNAL OF IMMUNOLOGY
- Network Topologies and Dynamics Leading to Endotoxin Tolerance and Priming in Innate Immune Cells
- (2012) Yan Fu et al. PLoS Computational Biology
- Molecular Mechanisms and Pathological Consequences of Endotoxin Tolerance and Priming
- (2011) Matthew Morris et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- The CD14bright CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population
- (2011) Manuela Rossol et al. ARTHRITIS AND RHEUMATISM
- FIMO: scanning for occurrences of a given motif
- (2011) Charles E. Grant et al. BIOINFORMATICS
- Examining Associations of Circulating Endotoxin With Nutritional Status, Inflammation, and Mortality in Hemodialysis Patients
- (2011) Usama Feroze et al. JOURNAL OF RENAL NUTRITION
- Reduction in endotoxemia, oxidative and inflammatory stress, and insulin resistance after Roux-en-Y gastric bypass surgery in patients with morbid obesity and type 2 diabetes mellitus
- (2011) Scott V. Monte et al. SURGERY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Inferring Regulatory Networks from Expression Data Using Tree-Based Methods
- (2010) Vân Anh Huynh-Thu et al. PLoS One
- Pharmacological Inhibition of C-C Chemokine Receptor 2 Decreases Macrophage Infiltration in the Aortic Root of the Human C-C Chemokine Receptor 2/Apolipoprotein E −/− Mouse: Magnetic Resonance Imaging Assessment
- (2009) Alan R. Olzinski et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival
- (2008) L. Landsman et al. BLOOD
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More