Moving Toward Patient-Tailored Treatment in ALS and FTD: The Potential of Genomic Assessment as a Tool for Biological Discovery and Trial Recruitment
出版年份 2021 全文链接
标题
Moving Toward Patient-Tailored Treatment in ALS and FTD: The Potential of Genomic Assessment as a Tool for Biological Discovery and Trial Recruitment
作者
关键词
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出版物
Frontiers in Neuroscience
Volume 15, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-03-01
DOI
10.3389/fnins.2021.639078
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tracking disease progression in familial and sporadic frontotemporal lobar degeneration: Recent findings from ARTFL and LEFFTDS
- (2020) Howard J. Rosen et al. Alzheimers & Dementia
- Primary lateral sclerosis: consensus diagnostic criteria
- (2020) Martin R Turner et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- The Overlapping Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
- (2020) Yevgeniya A. Abramzon et al. Frontiers in Neuroscience
- A proposal for new diagnostic criteria for ALS
- (2020) Jeremy M. Shefner et al. CLINICAL NEUROPHYSIOLOGY
- Moving towards multicenter therapeutic trials in ALS: feasibility of data pooling using different TSPO positron emission tomography (PET) radioligands.
- (2020) Donatienne Van Weehaeghe et al. JOURNAL OF NUCLEAR MEDICINE
- Phenotypic variability in ALS-FTD and effect on survival
- (2020) Rebekah M. Ahmed et al. NEUROLOGY
- Clinical and preclinical evidence of somatosensory involvement in amyotrophic lateral sclerosis
- (2020) Javier Riancho et al. BRITISH JOURNAL OF PHARMACOLOGY
- From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline
- (2020) Rajka Maria Liscic et al. Molecular Neurodegeneration
- Exploring human genomic diversity with gnomAD
- (2020) Linda Koch NATURE REVIEWS GENETICS
- Accumulation of phosphorylated TDP ‐43 in the cytoplasm of Schwann cells in a case of sporadic amyotrophic lateral sclerosis
- (2020) Keiko Nakamura‐Shindo et al. NEUROPATHOLOGY
- A Knowledge-Based Machine Learning Approach to Gene Prioritisation in Amyotrophic Lateral Sclerosis
- (2020) Daniel M. Bean et al. Genes
- A Systematic Review of Genotype–Phenotype Correlation across Cohorts Having Causal Mutations of Different Genes in ALS
- (2020) Owen Connolly et al. Journal of Personalized Medicine
- Genetic Testing for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
- (2020) Jennifer Roggenbuck et al. CLINICS IN LABORATORY MEDICINE
- Pathogenic Genome Signatures That Damage Motor Neurons in Amyotrophic Lateral Sclerosis
- (2020) Ali Yousefian-Jazi et al. Cells
- Machine Learning in Amyotrophic Lateral Sclerosis: Achievements, Pitfalls, and Future Directions
- (2019) Vincent Grollemund et al. Frontiers in Neuroscience
- Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates
- (2019) Giulia Vinceti et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
- (2019) Richard M. Tsai et al. Alzheimers Research & Therapy
- De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes
- (2019) Nirmal Vadgama et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response
- (2019) Corey J. Anderson et al. ACTA NEUROPATHOLOGICA
- An update on genetic frontotemporal dementia
- (2019) Caroline V. Greaves et al. JOURNAL OF NEUROLOGY
- Incidence of frontotemporal lobar degeneration in Italy
- (2019) Giancarlo Logroscino et al. NEUROLOGY
- Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS
- (2019) Hannah Rostalski et al. Frontiers in Neuroscience
- The complete costs of genome sequencing: a microcosting study in cancer and rare diseases from a single center in the United Kingdom
- (2019) Katharina Schwarze et al. GENETICS IN MEDICINE
- Neuroinflammation in frontotemporal dementia
- (2019) Fiona Bright et al. Nature Reviews Neurology
- Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
- (2019) Oleksandr Frei et al. Nature Communications
- Incidence of frontotemporal disorders in Olmsted County: A population-based study
- (2019) Pierpaolo Turcano et al. Alzheimers & Dementia
- A case of TDP-43 type C pathology presenting as nonfluent variant primary progressive aphasia
- (2019) Kerala L Adams-Carr et al. NEUROCASE
- Pharmacogenetic interactions in amyotrophic lateral sclerosis: a step closer to a cure?
- (2019) Ruben P. A. van Eijk et al. PHARMACOGENOMICS JOURNAL
- Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome
- (2019) Richard M. Tsai et al. JAMA Neurology
- Global variation in prevalence and incidence of amyotrophic lateral sclerosis: a systematic review and meta-analysis
- (2019) Lu Xu et al. JOURNAL OF NEUROLOGY
- Lysosomal Dysfunction at the Centre of Parkinson’s Disease and Frontotemporal Dementia/Amyotrophic Lateral Sclerosis
- (2019) Rebecca L. Wallings et al. TRENDS IN NEUROSCIENCES
- Genotype–phenotype links in frontotemporal lobar degeneration
- (2018) Sara Van Mossevelde et al. Nature Reviews Neurology
- Multimodal MRI quantification of the common neurostructural bases within the FTD-ALS continuum
- (2018) Chiara Crespi et al. NEUROBIOLOGY OF AGING
- Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
- (2018) Iris Broce et al. PLOS MEDICINE
- Cognitive and behavioural changes in PLS and PMA:challenging the concept of restricted phenotypes
- (2018) Bálint S de Vries et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease
- (2018) Iris J. Broce et al. ACTA NEUROPATHOLOGICA
- The genetic basis of disease
- (2018) Maria Jackson et al. Essays in Biochemistry
- The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects
- (2017) Cornelis Blauwendraat et al. GENETICS IN MEDICINE
- Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis
- (2017) Matthew D. Cykowski et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: Frequency of abnormality and effect on survival
- (2017) Zhouwei Xu et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- TREM2 in Neurodegenerative Diseases
- (2017) Taylor R. Jay et al. Molecular Neurodegeneration
- ATXN2 trinucleotide repeat length correlates with risk of ALS
- (2017) William Sproviero et al. NEUROBIOLOGY OF AGING
- Frontotemporal Dementia
- (2017) Nicholas T. Olney et al. NEUROLOGIC CLINICS
- Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials
- (2017) Ruben P.A. van Eijk et al. NEUROLOGY
- Neuroimaging patterns along the ALS-FTD spectrum: a multiparametric imaging study
- (2017) Taha Omer et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- ATXN2-AS, a gene antisense toATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis
- (2016) Pan P. Li et al. ANNALS OF NEUROLOGY
- Is the $1000 Genome as Near as We Think? A Cost Analysis of Next-Generation Sequencing
- (2016) Kirsten J.M. van Nimwegen et al. CLINICAL CHEMISTRY
- Survival in Frontotemporal Dementia Phenotypes: A Meta-Analysis
- (2016) Kalyani Kansal et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Therapy and clinical trials in frontotemporal dementia: past, present, and future
- (2016) Richard M. Tsai et al. JOURNAL OF NEUROCHEMISTRY
- The frontotemporal syndrome of ALS is associated with poor survival
- (2016) Rosanne Govaarts et al. JOURNAL OF NEUROLOGY
- Widespread structural brain involvement in ALS is not limited to theC9orf72repeat expansion
- (2016) Henk-Jan Westeneng et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
- (2016) Raffaele Ferrari et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
- (2016) Wouter van Rheenen et al. NATURE GENETICS
- Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage
- (2016) Sarah J. Hill et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Common Molecular Pathways in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
- (2016) Jochen H. Weishaupt et al. TRENDS IN MOLECULAR MEDICINE
- FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons
- (2016) Julia Higelin et al. Frontiers in Cellular Neuroscience
- Tau imaging in neurodegenerative diseases
- (2015) M. Dani et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Heritability of Amyotrophic Lateral Sclerosis
- (2015) Russell Lewis McLaughlin et al. JAMA Neurology
- A Multiancestral Genome-Wide Exome Array Study of Alzheimer Disease, Frontotemporal Dementia, and Progressive Supranuclear Palsy
- (2015) Jason A. Chen et al. JAMA Neurology
- Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis
- (2014) Wenzhi Tan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Amyotrophic lateral sclerosis: a long preclinical period?
- (2014) A. Eisen et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Frontotemporal dementia and its subtypes: a genome-wide association study
- (2014) Raffaele Ferrari et al. LANCET NEUROLOGY
- Genome-Wide Analysis of the Heritability of Amyotrophic Lateral Sclerosis
- (2014) Margaux F. Keller et al. JAMA Neurology
- Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors
- (2013) Ole A. Andreassen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- ACMG recommendations on incidental findings are flawed scientifically and ethically
- (2013) Neil A. Holtzman GENETICS IN MEDICINE
- A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis
- (2013) I. Fogh et al. HUMAN MOLECULAR GENETICS
- Basal ganglia involvement in amyotrophic lateral sclerosis
- (2013) P. Bede et al. NEUROLOGY
- Development and Validation of Pedigree Classification Criteria for Frontotemporal Lobar Degeneration
- (2013) Elisabeth M. Wood et al. JAMA Neurology
- Truncating mutations inFUS/TLSgive rise to a more aggressive ALS-phenotype than missense mutations: a clinico-genetic study in Germany
- (2012) S. Waibel et al. EUROPEAN JOURNAL OF NEUROLOGY
- C19orf12 mutations in neurodegeneration with brain iron accumulation mimicking juvenile amyotrophic lateral sclerosis
- (2012) M. Deschauer et al. JOURNAL OF NEUROLOGY
- Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
- (2012) Elisa Majounie et al. LANCET NEUROLOGY
- Phenotype and genotype analysis in amyotrophic lateral sclerosis with TARDBP gene mutations
- (2012) P. Corcia et al. NEUROLOGY
- Grey and White Matter Changes across the Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Continuum
- (2012) Patricia Lillo et al. PLoS One
- Neuropathological background of phenotypical variability in frontotemporal dementia
- (2011) Keith A. Josephs et al. ACTA NEUROPATHOLOGICA
- Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
- (2011) Katya Rascovsky et al. BRAIN
- Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients
- (2011) T. Lee et al. HUMAN MOLECULAR GENETICS
- An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28
- (2011) David R Owen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Estimating the Number of Persons with Frontotemporal Lobar Degeneration in the US Population
- (2011) David S. Knopman et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Classification of primary progressive aphasia and its variants
- (2011) M. L. Gorno-Tempini et al. NEUROLOGY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- An estimate of amyotrophic lateral sclerosis heritability using twin data
- (2010) A. Al-Chalabi et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Primary progressive aphasia: clinicopathological correlations
- (2010) Murray Grossman Nature Reviews Neurology
- Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies
- (2010) Felix Geser et al. NEUROPATHOLOGY
- Study of 962 patients indicates progressive muscular atrophy is a form of ALS
- (2009) W. -K. Kim et al. NEUROLOGY
- The heritability and genetics of frontotemporal lobar degeneration
- (2009) J. D. Rohrer et al. NEUROLOGY
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