Polθ promotes the repair of 5′-DNA-protein crosslinks by microhomology-mediated end-joining
出版年份 2021 全文链接
标题
Polθ promotes the repair of 5′-DNA-protein crosslinks by microhomology-mediated end-joining
作者
关键词
-
出版物
Cell Reports
Volume 34, Issue 10, Pages 108820
出版商
Elsevier BV
发表日期
2021-03-10
DOI
10.1016/j.celrep.2021.108820
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining
- (2020) J. A. Kamp et al. Nature Communications
- DNA Polymerase theta (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse
- (2019) Zi Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
- (2019) Janin Grajcarek et al. Nature Communications
- Molecular basis of microhomology-mediated end-joining by purified full-length Polθ
- (2019) Samuel J. Black et al. Nature Communications
- The MRE11–RAD50–NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair
- (2018) Aleem Syed et al. Annual Review of Biochemistry
- Terminal deoxynucleotidyltransferase: the story of an untemplated DNA polymerase capable of DNA bridging and templated synthesis across strands
- (2018) Jérôme Loc’h et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity
- (2018) Eleonora Juarez et al. DNA REPAIR
- Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts
- (2018) Nicolai B. Larsen et al. MOLECULAR CELL
- Mechanisms of DNA–protein crosslink repair
- (2017) Julian Stingele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The helicase domain of Polθ counteracts RPA to promote alt-NHEJ
- (2017) Pedro A Mateos-Gomez et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The helicase domain of Polθ counteracts RPA to promote alt-NHEJ
- (2017) Pedro A Mateos-Gomez et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- MRN, CtIP, and BRCA1 mediate repair of topoisomerase II–DNA adducts
- (2016) Tomas Aparicio et al. JOURNAL OF CELL BIOLOGY
- Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes
- (2016) Nguyen Ngoc Hoa et al. MOLECULAR CELL
- Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease Machine Specific for Protein-DNA Adducts
- (2016) Rajashree A. Deshpande et al. MOLECULAR CELL
- A role for human homologous recombination factors in suppressing microhomology-mediated end joining
- (2016) Sara Ahrabi et al. NUCLEIC ACIDS RESEARCH
- The structure of ends determines the pathway choice and Mre11 nuclease dependency of DNA double-strand break repair
- (2016) Shuren Liao et al. NUCLEIC ACIDS RESEARCH
- Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining
- (2016) Guangqing Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining
- (2016) Tatiana Kent et al. eLife
- DNA Polymerase θ: A Unique Multifunctional End-Joining Machine
- (2016) Samuel Black et al. Genes
- Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
- (2015) Raphael Ceccaldi et al. NATURE
- Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination
- (2015) Pedro A. Mateos-Gomez et al. NATURE
- Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
- (2015) Tatiana Kent et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?
- (2015) Agnel Sfeir et al. TRENDS IN BIOCHEMICAL SCIENCES
- Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis
- (2015) Robin van Schendel et al. Nature Communications
- Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
- (2015) Tatiana Kent et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2)
- (2014) Yves Pommier et al. DNA REPAIR
- Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection
- (2014) Nodar Makharashvili et al. MOLECULAR CELL
- Sae2 promotes dsDNA endonuclease activity within Mre11–Rad50–Xrs2 to resect DNA breaks
- (2014) Elda Cannavo et al. NATURE
- Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ
- (2014) Matthew J. Yousefzadeh et al. PLoS Genetics
- Compensatory Functions and Interdependency of the DNA-Binding Domain of BRCA2 with the BRCA1-PALB2-BRCA2 Complex
- (2013) M. Al Abo et al. CANCER RESEARCH
- Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
- (2013) L. N. Truong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP2–Dependent Non-Homologous End-Joining Protects against Topoisomerase II–Induced DNA Breaks and Genome Instability in Cells and In Vivo
- (2013) Fernando Gómez-Herreros et al. PLoS Genetics
- Biochemical Characterization of Human Tyrosyl-DNA Phosphodiesterase 2 (TDP2/TTRAP)
- (2012) Rui Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural basis for recognition of 5′-phosphotyrosine adducts by Tdp2
- (2012) Ke Shi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown
- (2010) Geoff S. Higgins et al. CANCER RESEARCH
- An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
- (2010) Yu Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila
- (2010) Sze Ham Chan et al. PLoS Genetics
- Collaborative Action of Brca1 and CtIP in Elimination of Covalent Modifications from Double-Strand Breaks to Facilitate Subsequent Break Repair
- (2010) Kyoko Nakamura et al. PLoS Genetics
- Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells
- (2009) Toshiaki Nakano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More