Parsing the differences in affected with LHON: genetic versus environmental triggers of disease conversion

Mitochondrial DNA copy number differentiates the Leber’s hereditary optic neuropathy affected individuals from the unaffected mutation carriers

(2015) Angelica Bianco et al.   BRAIN

Cigarette toxicity triggers Leber’s hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways

(2015) L Giordano et al.   Cell Death & Disease

Leber’s hereditary optic neuropathy with late disease onset: clinical and molecular characteristics of 20 patients

(2014) Konstantin Dimitriadis et al.   Orphanet Journal of Rare Diseases

Efficient mitochondrial biogenesis drives incomplete penetrance in Leber’s hereditary optic neuropathy

(2013) Carla Giordano et al.   BRAIN

Idebenone Treatment In Leber's Hereditary Optic Neuropathy

(2011) V. Carelli et al.   BRAIN

Oestrogens ameliorate mitochondrial dysfunction in Leber’s hereditary optic neuropathy

(2010) Carla Giordano et al.   BRAIN

Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies

(2010) Chiara La Morgia et al.   BRAIN

Antituberculosis medication as a possible epigenetic factor of Leber's hereditary optic neuropathy

(2010) Je Hyun Seo et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Mitochondrial optic neuropathies – Disease mechanisms and therapeutic strategies

(2010) Patrick Yu-Wai-Man et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Leber hereditary optic neuropathy: bad habits, bad vision?

(2009) N. J. Newman   BRAIN

Gene–environment interactions in Leber hereditary optic neuropathy

(2009) Matthew Anthony Kirkman et al.   BRAIN

The Background of Mitochondrial DNA Haplogroup J Increases the Sensitivity of Leber's Hereditary Optic Neuropathy Cells to 2,5-Hexanedione Toxicity

(2009) Anna Ghelli et al.   PLoS One

Leber Hereditary Optic Neuropathy Presenting in a 75-Year-Old Man

(2008) Patrick Yu-Wai-Man et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

You're Too Old for That

(2008) Vinay A. Shah et al.   SURVEY OF OPHTHALMOLOGY