Neural Computations of Threat

Impairments to Consolidation, Reconsolidation, and Long-Term Memory Maintenance Lead to Memory Erasure

(2020) Josué Haubrich et al.   Annual Review of Neuroscience

Anticipatory feelings: neural correlates and linguistic markers

(2020) Elka Stefanova et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Space, Time, and Fear: Survival Computations along Defensive Circuits

(2020) Dean Mobbs et al.   TRENDS IN COGNITIVE SCIENCES

Retrieval-Extinction and Relapse Prevention: Rewriting Maladaptive Drug Memories?

(2020) Eloise J. Kuijer et al.   Frontiers in Behavioral Neuroscience

Decomposing the neural pathways in a simple, value-based choice

(2020) Timothy R. Koscik et al.   NEUROIMAGE

Rethinking post-traumatic stress disorder – A predictive processing perspective

(2020) Tobias Kube et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dissociable neural signatures of passive extinction and instrumental control over threatening events

(2020) Nadine Wanke et al.   Social Cognitive and Affective Neuroscience

Unanticipated Stressful and Rewarding Experiences Engage the Same Prefrontal Cortex and Ventral Tegmental Area Neuronal Populations

(2020) Alberto Del Arco et al.   eNeuro

Divergent projections of the prelimbic cortex bidirectionally regulate active avoidance

(2020) Maria M Diehl et al.   eLife

Neural computations of threat in the aftermath of combat trauma

(2019) Philipp Homan et al.   NATURE NEUROSCIENCE

Neurochemical and molecular mechanisms underlying the retrieval-extinction effect

(2019) Emma N. Cahill et al.   PSYCHOPHARMACOLOGY

Social threat learning transfers to decision making in humans

(2019) Björn Lindström et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Augmentation of Extinction and Inhibitory Learning in Anxiety and Trauma-Related Disorders

(2019) Lauren A.M. Lebois et al.   Annual Review of Clinical Psychology

Adaptive learning under expected and unexpected uncertainty

(2019) Alireza Soltani et al.   NATURE REVIEWS NEUROSCIENCE

Current understanding of fear learning and memory in humans and animal models and the value of a linguistic approach for analyzing fear learning and memory in humans

(2019) Jacob Raber et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Biology of Human Resilience: Opportunities for Enhancing Resilience across the Lifespan

(2019) Adriana Feder et al.   BIOLOGICAL PSYCHIATRY

The Functional Roles of the Amygdala and Prefrontal Cortex in Processing Uncertainty

(2019) Oriel FeldmanHall et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Stress transforms lateral habenula reward responses into punishment signals

(2019) Steven J. Shabel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential replay of nonspatial task states in the human hippocampus

(2019) Nicolas W. Schuck et al.   SCIENCE

Understanding the Higher-Order Approach to Consciousness

(2019) Richard Brown et al.   TRENDS IN COGNITIVE SCIENCES

The dorsomedial prefrontal cortex computes task-invariant relative subjective value for self and other

(2019) Matthew Piva et al.   eLife

Altered learning under uncertainty in unmedicated mood and anxiety disorders

(2019) Jessica Aylward et al.   Nature Human Behaviour

Slow escape decisions are swayed by trait anxiety

(2019) Bowen J. Fung et al.   Nature Human Behaviour

The Misestimation of Uncertainty in Affective Disorders

(2019) Erdem Pulcu et al.   TRENDS IN COGNITIVE SCIENCES

The study of active avoidance: A platform for discussion

(2019) Maria M. Diehl et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Computational Markers of Risky Decision-making for Identification of Temporal Windows of Vulnerability to Opioid Use in a Real-world Clinical Setting

(2019) Anna B. Konova et al.   JAMA Psychiatry

Basolateral amygdala circuitry in positive and negative valence

(2018) Pia-Kelsey O’Neill et al.   CURRENT OPINION IN NEUROBIOLOGY

Surviving threats: neural circuit and computational implications of a new taxonomy of defensive behaviour

(2018) Joseph LeDoux et al.   NATURE REVIEWS NEUROSCIENCE

Balancing New against Old Information: The Role of Puzzlement Surprise in Learning

(2018) Mohammadjavad Faraji et al.   NEURAL COMPUTATION

A common neural network differentially mediates direct and social fear learning

(2018) Björn Lindström et al.   NEUROIMAGE

Amygdala Functional and Structural Connectivity Predicts Individual Risk Tolerance

(2018) Wi Hoon Jung et al.   NEURON

How cognitive and reactive fear circuits optimize escape decisions in humans

(2018) Song Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reminder duration determines threat memory modification in humans

(2018) Jingchu Hu et al.   Scientific Reports

Associability-modulated loss learning is increased in posttraumatic stress disorder

(2018) Vanessa M Brown et al.   eLife

Prefrontal circuits signaling active avoidance retrieval and extinction

(2018) Freddyson J. Martínez-Rivera et al.   PSYCHOPHARMACOLOGY

Human Pavlovian fear conditioning conforms to probabilistic learning

(2018) Athina Tzovara et al.   PLoS Computational Biology

Are we of two minds?

(2018) Nathaniel D. Daw   NATURE NEUROSCIENCE

Attenuating Neural Threat Expression with Imagination

(2018) Marianne Cumella Reddan et al.   NEURON

Reconsolidation/destabilization, extinction and forgetting of fear memory as therapeutic targets for PTSD

(2018) Satoshi Kida   PSYCHOPHARMACOLOGY

Threat-related disorders as persistent motivational states of defense

(2018) Felipe Corchs et al.   Current Opinion in Behavioral Sciences

Neural Mechanisms of Updating under Reducible and Irreducible Uncertainty

(2017) Kenji Kobayashi et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Inhibition Reveals Distinct Roles for Basolateral Amygdala Activity at Discrete Time Points during Risky Decision Making

(2017) Caitlin A. Orsini et al.   JOURNAL OF NEUROSCIENCE

Active Avoidance: Neural Mechanisms and Attenuation of Pavlovian Conditioned Responding

(2017) Emily A. Boeke et al.   JOURNAL OF NEUROSCIENCE

Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment

(2017) Anthony Burgos-Robles et al.   NATURE NEUROSCIENCE

Algorithms for survival: a comparative perspective on emotions

(2017) Dominik R. Bach et al.   NATURE REVIEWS NEUROSCIENCE

Tackling maladaptive memories through reconsolidation: From neural to clinical science

(2017) James W.B. Elsey et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Metaplasticity as a Neural Substrate for Adaptive Learning and Choice under Uncertainty

(2017) Shiva Farashahi et al.   NEURON

Agency and the Calibration of Motivated Behavior

(2017) Justin M. Moscarello et al.   TRENDS IN COGNITIVE SCIENCES

Social Fear Learning: from Animal Models to Human Function

(2017) Jacek Debiec et al.   TRENDS IN COGNITIVE SCIENCES

An Update on Memory Reconsolidation Updating

(2017) Jonathan L.C. Lee et al.   TRENDS IN COGNITIVE SCIENCES

Distributed neural representation of saliency controlled value and category during anticipation of rewards and punishments

(2017) Zhihao Zhang et al.   Nature Communications

Using Neuroscience to Help Understand Fear and Anxiety: A Two-System Framework

(2016) Joseph E. LeDoux et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Efficacy of Exposure Therapy for Anxiety-Related Disorders and Its Underlying Mechanisms: The Case of OCD and PTSD

(2016) Edna B. Foa et al.   Annual Review of Clinical Psychology

Behavioral and Neural Mechanisms of Overgeneralization in Anxiety

(2016) Offir Laufer et al.   CURRENT BIOLOGY

Dissociable Learning Processes Underlie Human Pain Conditioning

(2016) Suyi Zhang et al.   CURRENT BIOLOGY

POSTTRAUMATIC STRESS SYMPTOMS AND AVERSION TO AMBIGUOUS LOSSES IN COMBAT VETERANS

(2016) Lital Ruderman et al.   DEPRESSION AND ANXIETY

The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm

(2016) J E LeDoux et al.   MOLECULAR PSYCHIATRY

A feedback neural circuit for calibrating aversive memory strength

(2016) Takaaki Ozawa et al.   NATURE NEUROSCIENCE

Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval

(2016) Anna Beyeler et al.   NEURON

Neuroanatomical Substrates for Risk Behavior

(2016) Ifat Levy   NEUROSCIENTIST

Neural signals of vicarious extinction learning

(2016) Armita Golkar et al.   Social Cognitive and Affective Neuroscience

Mood as Representation of Momentum

(2016) Eran Eldar et al.   TRENDS IN COGNITIVE SCIENCES

New Learning and Unlearning: Strangers or Accomplices in Threat Memory Attenuation?

(2016) Roger L. Clem et al.   TRENDS IN NEUROSCIENCES

Neuroanatomy accounts for age-related changes in risk preferences

(2016) Michael A. Grubb et al.   Nature Communications

Computations of uncertainty mediate acute stress responses in humans

(2016) Archy O. de Berker et al.   Nature Communications

Instructed knowledge shapes feedback-driven aversive learning in striatum and orbitofrontal cortex, but not the amygdala

(2016) Lauren Y Atlas et al.   eLife

Characterizing a psychiatric symptom dimension related to deficits in goal-directed control

(2016) Claire M Gillan et al.   eLife

Minding the findings: Let's not miss the message of memory reconsolidation research for psychotherapy

(2015) Bruce Ecker et al.   BEHAVIORAL AND BRAIN SCIENCES

Learning models of PTSD: Theoretical accounts and psychobiological evidence

(2015) Shmuel Lissek et al.   INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY

Dissociable Roles for the Basolateral Amygdala and Orbitofrontal Cortex in Decision-Making under Risk of Punishment

(2015) C. A. Orsini et al.   JOURNAL OF NEUROSCIENCE

Decision-making under uncertainty in obsessive–compulsive disorder

(2015) Helen Pushkarskaya et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Individual differences in learning predict the return of fear

(2015) Samuel J. Gershman et al.   LEARNING & BEHAVIOR

A circuit mechanism for differentiating positive and negative associations

(2015) Praneeth Namburi et al.   NATURE

From circuits to behaviour in the amygdala

(2015) Patricia H. Janak et al.   NATURE

Rethinking Extinction

(2015) Joseph E. Dunsmoor et al.   NEURON

The interaction of acute and chronic stress impairs model-based behavioral control

(2015) Christoph Radenbach et al.   PSYCHONEUROENDOCRINOLOGY

Individual differences in sensitivity to reward and punishment and neural activity during reward and avoidance learning

(2015) Sang Hee Kim et al.   Social Cognitive and Affective Neuroscience

A Unifying Probabilistic View of Associative Learning

(2015) Samuel J. Gershman   PLoS Computational Biology

The ecology of human fear: survival optimization and the nervous system

(2015) Dean Mobbs et al.   Frontiers in Neuroscience

Memory reconsolidation, emotional arousal, and the process of change in psychotherapy: New insights from brain science

(2014) Richard D. Lane et al.   BEHAVIORAL AND BRAIN SCIENCES

Human reconsolidation: A reactivation and update

(2014) Thomas Agren   BRAIN RESEARCH BULLETIN

Neuroanatomy Predicts Individual Risk Attitudes

(2014) S. Gilaie-Dotan et al.   JOURNAL OF NEUROSCIENCE

Aversive Prediction Error Signals in the Amygdala

(2014) S. B. McHugh et al.   JOURNAL OF NEUROSCIENCE

Taking Action in the Face of Threat: Neural Synchronization Predicts Adaptive Coping

(2014) K. A. Collins et al.   JOURNAL OF NEUROSCIENCE

Encoding of fear learning and memory in distributed neuronal circuits

(2014) Cyril Herry et al.   NATURE NEUROSCIENCE

Reward Value Comparison via Mutual Inhibition in Ventromedial Prefrontal Cortex

(2014) Caleb E. Strait et al.   NEURON

Functionally Dissociable Influences on Learning Rate in a Dynamic Environment

(2014) Joseph T. McGuire et al.   NEURON

Disentangling neural representations of value and salience in the human brain

(2014) Thorsten Kahnt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coming to terms with fear

(2014) J. E. LeDoux   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fear Extinction and Relapse: State of the Art

(2013) Bram Vervliet et al.   Annual Review of Clinical Psychology

Active Avoidance Learning Requires Prefrontal Suppression of Amygdala-Mediated Defensive Reactions

(2013) J. M. Moscarello et al.   JOURNAL OF NEUROSCIENCE

Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective

(2013) Dan W. Grupe et al.   NATURE REVIEWS NEUROSCIENCE

The valuation system: A coordinate-based meta-analysis of BOLD fMRI experiments examining neural correlates of subjective value

(2013) Oscar Bartra et al.   NEUROIMAGE

Functional Connectivity between Amygdala and Cingulate Cortex for Adaptive Aversive Learning

(2013) Oded Klavir et al.   NEURON

The Neural Representation of Unexpected Uncertainty during Value-Based Decision Making

(2013) Elise Payzan-LeNestour et al.   NEURON

Prediction error in reinforcement learning: A meta-analysis of neuroimaging studies

(2013) Jane Garrison et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Like cognitive function, decision making across the life span shows profound age-related changes

(2013) A. Tymula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Working-memory capacity protects model-based learning from stress

(2013) A. R. Otto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aversive stimuli and loss in the mesocorticolimbic dopamine system

(2013) Andrew M. Brooks et al.   TRENDS IN COGNITIVE SCIENCES

A causal model of post-traumatic stress disorder: disentangling predisposed from acquired neural abnormalities

(2013) Roee Admon et al.   TRENDS IN COGNITIVE SCIENCES

Gradual extinction prevents the return of fear: implications for the discovery of state

(2013) Samuel J. Gershman et al.   Frontiers in Behavioral Neuroscience

The root of all value: a neural common currency for choice

(2012) Dino J Levy et al.   CURRENT OPINION IN NEUROBIOLOGY

Regionally Distinct Processing of Rewards and Punishments by the Primate Ventromedial Prefrontal Cortex

(2012) I. E. Monosov et al.   JOURNAL OF NEUROSCIENCE

Rational regulation of learning dynamics by pupil-linked arousal systems

(2012) Matthew R Nassar et al.   NATURE NEUROSCIENCE

Mechanisms underlying cortical activity during value-guided choice

(2012) Laurence T Hunt et al.   NATURE NEUROSCIENCE

The many paths to fear

(2012) Cornelius T. Gross et al.   NATURE REVIEWS NEUROSCIENCE

Rethinking the Emotional Brain

(2012) Joseph LeDoux   NEURON

Disruption of Reconsolidation Erases a Fear Memory Trace in the Human Amygdala

(2012) T. Agren et al.   SCIENCE

A functional architecture of the human brain: emerging insights from the science of emotion

(2012) Kristen A. Lindquist et al.   TRENDS IN COGNITIVE SCIENCES

Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Prolonged exposure therapy: past, present, and future

(2011) Edna B. Foa   DEPRESSION AND ANXIETY

A Bayesian foundation for individual learning under uncertainty

(2011) Christoph Mathys   Frontiers in Human Neuroscience

Neurobiology of Value Integration: When Value Impacts Valuation

(2011) S. Q. Park et al.   JOURNAL OF NEUROSCIENCE

Comparing Apples and Oranges: Using Reward-Specific and Reward-General Subjective Value Representation in the Brain

(2011) D. J. Levy et al.   JOURNAL OF NEUROSCIENCE

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Differential roles of human striatum and amygdala in associative learning

(2011) Jian Li et al.   NATURE NEUROSCIENCE

Auditory aversive learning increases discrimination thresholds

(2011) Jennifer Resnik et al.   NATURE NEUROSCIENCE

Deconstructing risk: Separable encoding of variance and skewness in the brain

(2011) Mkael Symmonds et al.   NEUROIMAGE

Placing prediction into the fear circuit

(2011) Gavan P. McNally et al.   TRENDS IN NEUROSCIENCES

Risk, Unexpected Uncertainty, and Estimation Uncertainty: Bayesian Learning in Unstable Settings

(2011) Elise Payzan-LeNestour et al.   PLoS Computational Biology

Dissociating Valuation and Saliency Signals during Decision-Making

(2010) A. Litt et al.   CEREBRAL CORTEX

A Behavioral and Neural Evaluation of Prospective Decision-Making under Risk

(2010) M. Symmonds et al.   JOURNAL OF NEUROSCIENCE

Neural Correlates of Variations in Event Processing during Learning in Basolateral Amygdala

(2010) M. R. Roesch et al.   JOURNAL OF NEUROSCIENCE

An Approximately Bayesian Delta-Rule Model Explains the Dynamics of Belief Updating in a Changing Environment

(2010) M. R. Nassar et al.   JOURNAL OF NEUROSCIENCE

Dopamine in Motivational Control: Rewarding, Aversive, and Alerting

(2010) Ethan S. Bromberg-Martin et al.   NEURON

Common and distinct networks underlying reward valence and processing stages: A meta-analysis of functional neuroimaging studies

(2010) Xun Liu et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Overlapping neural systems mediating extinction, reversal and regulation of fear

(2010) Daniela Schiller et al.   TRENDS IN COGNITIVE SCIENCES

Segregated and Integrated Coding of Reward and Punishment in the Cingulate Cortex

(2009) Juri Fujiwara et al.   JOURNAL OF NEUROPHYSIOLOGY

Neural Representation of Subjective Value Under Risk and Ambiguity

(2009) Ifat Levy et al.   JOURNAL OF NEUROPHYSIOLOGY

Neural Correlates of Value, Risk, and Risk Aversion Contributing to Decision Making under Risk

(2009) G. I. Christopoulos et al.   JOURNAL OF NEUROSCIENCE

Neural Activity Associated with the Passive Prediction of Ambiguity and Risk for Aversive Events

(2009) D. R. Bach et al.   JOURNAL OF NEUROSCIENCE

Sustained Conditioned Responses in Prelimbic Prefrontal Neurons Are Correlated with Fear Expression and Extinction Failure

(2009) A. Burgos-Robles et al.   JOURNAL OF NEUROSCIENCE

Preventing the return of fear in humans using reconsolidation update mechanisms

(2009) Daniela Schiller et al.   NATURE

A single standard for memory: the case for reconsolidation

(2009) Karim Nader et al.   NATURE REVIEWS NEUROSCIENCE

Neural foundations of risk–return trade-off in investment decisions

(2009) Peter N.C. Mohr et al.   NEUROIMAGE

Amygdala Inhibitory Circuits and the Control of Fear Memory

(2009) Ingrid Ehrlich et al.   NEURON

The Neurobiology of Decision: Consensus and Controversy

(2009) Joseph W. Kable et al.   NEURON

Extinction-Reconsolidation Boundaries: Key to Persistent Attenuation of Fear Memories

(2009) M.-H. Monfils et al.   SCIENCE

Reconsolidation: maintaining memory relevance

(2009) Jonathan L.C. Lee   TRENDS IN NEUROSCIENCES

Avoiding negative outcomes: tracking the mechanisms of avoidance learning in humans during fear conditioning

(2009) Mauricio R. Delgado   Frontiers in Behavioral Neuroscience

Human Insula Activation Reflects Risk Prediction Errors As Well As Risk

(2008) K. Preuschoff et al.   JOURNAL OF NEUROSCIENCE

From Fear to Safety and Back: Reversal of Fear in the Human Brain

(2008) D. Schiller et al.   JOURNAL OF NEUROSCIENCE

Switching on and off fear by distinct neuronal circuits

(2008) Cyril Herry et al.   NATURE

Emotional environments retune the valence of appetitive versus fearful functions in nucleus accumbens

(2008) Sheila M Reynolds et al.   NATURE NEUROSCIENCE

The role of the striatum in aversive learning and aversive prediction errors

(2008) M. R Delgado et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES