Article
Food Science & Technology
Gisoo Maleki, Ernst J. Woltering, M. R. Mozafari
Summary: This review article discusses the potential applications of chitosan-based carriers as encapsulating agents in the food industry. Chitosan can protect bioactive ingredients in food from environmental factors and has been extensively used as a carrier for delivering bioactive ingredients.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Ali A. Altam, Liping Zhu, Dafaalla Babiker, Hajo Yagoub, Shuguang Yang
Summary: CMC@CHI beads fabricated by interfacial complexation have a core-shell structure, allowing them to adsorb and release dyes with different charge status via electrostatic interaction, and showing potential applications.
PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Huijuan Jing, Xiaojing Du, Ling Mo, Hongxin Wang
Summary: Carboxymethyl chitosan (CMCS)-based self-coacervates have shown great potential in drug oral delivery due to their pH-responsive properties and stability in a wide pH range. These self-coacervates also exhibit excellent encapsulation efficiency and loading capacity for lactoferrin (LF) encapsulation, protecting LF from hydrolysis during simulated gastric digestion. Overall, CMCS self-coacervation can be utilized as a pH-responsive encapsulation and delivery strategy.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Yuanfei Ge, Jinyong Wu, Min Pang, Dan Hu, Zhongkui Li, Xiangqin Wang, Lijie Sun, Xiangsong Chen, Jianming Yao
Summary: In this study, CNeuAc hydrogels were developed using CMCS and NeuAc to encapsulate Pediococcus pentosaceus QK-1. The hydrogel demonstrated optimal performance at a C-NeuAc concentration of 3% (w/v), and showed excellent biocompatibility and low cytotoxicity. It also effectively protected the viability of the probiotic in simulated gastric fluid and gastrointestinal tract.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Applied
Zheng Jin, Gaowei Hu, Kai Zhao
Summary: This study demonstrated that the synthesized M-N-2-HACC/N-CMCS nanoparticles showed high efficiency in mucosal delivery by utilizing the interaction with mucosal sites for drug release and delivery.
CARBOHYDRATE POLYMERS
(2022)
Article
Biotechnology & Applied Microbiology
Li Xu, Zhanying Ren, Guolin Li, Danni Xu, Jiaqian Miao, Jingxuan Ju, Xuan Mo, Xianghui Wang, Hongping Deng, Min Xu
Summary: A liver-targeting gadolinium-based MRI contrast agent was developed using galactose functionalized o-carboxymethyl chitosan, which exhibited higher hepatocyte uptake, excellent biocompatibility, and better T1-weighted signal enhancement in the liver. The agent showed good safety in vivo at a specific dose.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Xin Zhang, Yangjia Li, Zhenyao Wu, Jie Li, Junjian Li, Shiming Deng, Guijin Liu
Summary: The objective of this work is to develop zein-based nanoparticles for the delivery of natural polyphenols. Through the atomizing/antisolvent precipitation process, carboxymethyl chitosan-coated zein/soy lecithin nanoparticles were successfully fabricated. These nanoparticles showed desirable redispersibility and physicochemical stability. The encapsulation of resveratrol in the optimized zein-based nanoparticles resulted in improved dissolution rate, bioaccessibility, and scavenging activity compared to free resveratrol. The nanoparticles also exhibited a higher retention rate during storage. Therefore, zein-based nanoparticles have great potential as carriers for natural polyphenols.
Article
Chemistry, Applied
Xiangwei Zhu, Jianjun Chen, Yuxi Hu, Ni Zhang, Yuqing Fu, Xiaoqiang Chen
Summary: This study successfully synthesized a new type of CMC/QCS (CQ) particles and encapsulated curcumin in the prepared CQ-stabilized emulsion, demonstrating good emulsion stability and reduced degradation rate against various environmental stresses.
FOOD HYDROCOLLOIDS
(2021)
Article
Polymer Science
Tanpong Chaiwarit, Sarana Rose Sommano, Pornchai Rachtanapun, Nutthapong Kantrong, Warintorn Ruksiriwanich, Mont Kumpugdee-Vollrath, Pensak Jantrawut
Summary: Polymeric nanoparticles, specifically CMCS-Ca2+ nanoparticles, loaded with clindamycin HCl demonstrated potential for modifying the drug release of small hydrophilic antibiotics. Ultrasonication with experimental design was utilized to produce these nanoparticles, and it was discovered that the size of nanoparticles had an inverse relationship with the drug content as well as the release rate.
Article
Biochemistry & Molecular Biology
Chengpeng Li, Xiaoyan Luo, Lefan Li, Ying Cai, Xinhuang Kang, Puwang Li
Summary: In this study, a method for improving the loading of citral in nanofibers was proposed and used to develop an anti-infection dressing. The dressing showed good antibacterial performance and hemocompatibility, and could promote cell proliferation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Jingjing Wang, Jun Wei
Summary: Zr(IV)-crosslinked carboxymethyl cellulose/carboxymethyl chitosan hydrogels were prepared as adsorbents for phosphate removal. The adsorption capacity of the hydrogel for PO4 increased with the content of PEG, reaching equilibrium within 400 minutes. The adsorption mechanism involved electrostatic interaction and ion exchange.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Environmental Sciences
Sheng-nan Li, Hao Wu, Rui-quan Hou, Jing-tong Zhou, Su-kun Lin, Kun-yu Zhao, Rui-fei Wang, Su-qing Huang, Zhi-xiang Zhang
Summary: This study examined the stress response of Apis cerana cerana after ingestion of high concentrations of O-CMC-NPs. The results showed that high concentrations of O-CMC-NPs increased the activity of antioxidant and detoxifying enzymes in A. cerana and affected the relative abundance of intestinal flora.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Jonathan Wilhelm, Manuel Quinones-Perez, Jian Wang, Xu Wang, Vijay S. Basava, Jinming Gao
Summary: This study investigated the relationship between antigen properties and encapsulation efficiency, revealing that peptide loading efficiency is mainly determined by the properties of peptide antigens. Particularly, a phase transition event of antigenic peptides from random coils to α-helical structure was found to be crucial for loading inside PC7A nanoparticles.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Biochemistry & Molecular Biology
Panpan Song, Nannan Song, Li Li, Minghao Wu, Zhongxia Lu, Xia Zhao
Summary: A pH/reduction-sensitive carboxymethyl chitosan nanogel modified by targeting peptide angiopep-2 loaded with doxorubicin shows promising potential for targeted chemotherapy of glioblastoma. The targeted nanogel exhibited good stability, biocompatibility, and enhanced BBB penetration and tumor targeting ability, leading to higher drug uptake and stronger antitumor activity compared to nontargeted nanogels. This innovative nanogel platform with pH/reduction dual-stimuli response may hold great significance for GBM-targeted therapy.
Article
Biochemistry & Molecular Biology
Qian Liu, Zhenrong Tan, Dafeng Zheng, Xueqing Qiu
Summary: A magnetic delivery system for targeted drug was developed using aminated lignosulfonate (ALS) and carboxymethyl chitosan (CMCS) to fabricate nano Fe3O4 with pH responsiveness. The system successfully loaded doxorubicin hydrochloride (DOX) and demonstrated controlled release of the drug. The particle size ranged from 79.9-169.9 nm under optimized conditions and exhibited excellent pH responsiveness. The drug-loaded particles showed significant growth inhibition on cancer cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Energy & Fuels
Syafiqah Md Nadzir, Norjan Yusof, Norazela Nordin, Hanisom Abdullah, Azlan Kamari
Summary: By optimizing the growth conditions, this study successfully increased the lipid, carbohydrate, and biomass productivity of T. obliquus, demonstrating its potential as a promising feedstock for biofuel production.
Article
Chemistry, Multidisciplinary
S. T. S. Wong, A. Kamari, A. M. Jaafar, M. Z. Hussein, H. Othman, H. Abdullah, N. Yusof, N. Hashim
ENVIRONMENTAL CHEMISTRY LETTERS
(2020)
Review
Environmental Sciences
J. Jumadi, A. Kamari, J. S. J. Hargreaves, N. Yusof
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2020)
Article
Chemistry, Inorganic & Nuclear
Nurul Husna As Saedah Bain, Noorshida Mohd Ali, Yusnita Juahir, Norhayati Hashim, Illyas Md Isa, Azmi Mohamed, Azlan Kamari, El Hassane Anouar, Bohari Mohd Yamin, Amalina Mohd Tajuddin, Muhammad Hazim Baharudin
Article
Chemistry, Multidisciplinary
Is Fatimah, Ganjar Fadillah, Imam Sahroni, Azlan Kamari, Suresh Sagadevan, Ruey-An Doong
Summary: The study synthesized ZnO/SiO2 nanocomposites using bamboo leaf ash (BLA) and tested their photocatalytic activity for rhodamine B decolorization. The nanocomposites showed promising results in terms of efficiency and reusability, making them a potential candidate for the degradation of dye-polluted water.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Article
Materials Science, Textiles
Azlan Kamari, Siti Najiah Mohd Yusoff, Siew Tin Susana Wong, Esther Phillip, Justin S. J. Hargreaves, Hidayatulfathi Othman
Summary: In this study, poly(epsilon-caprolactrone) nanocapsules loaded with betel essential oil were used as anti-mosquito spray formulations for cotton and polyester fabrics for the first time. The release and retention of the oil on the fabrics were determined, and the repellent activity was evaluated. The nanocapsules exhibited high encapsulation efficiency and stability, increasing the durability of the fabrics and providing good mosquito repellency.
JOURNAL OF THE TEXTILE INSTITUTE
(2023)
Article
Engineering, Multidisciplinary
Norazela Nordin, Norjan Yusoff, Syafiqah Md Nadzir, Azlan Kamari, Mohd Zulkhairi Mohd Yusoff
Summary: This study applies statistical optimization methods to determine the effect of NO3- concentration, light intensity, and NaHCO3 concentration on the biomass, lipid, and carbohydrate productivities of C. vulgaris. The results provide optimal conditions for highest biomass, lipid, and carbohydrate productivities, enabling the production of microalgae-based biodiesel that complies with international standards.
JURNAL TEKNOLOGI-SCIENCES & ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Nurul Husna As Saedah Bain, Noorshida Mohd Ali, Yusnita Juahir, Norhayati Hashim, Illyas Md Isa, Azmi Mohamed, Azlan Kamari, Bohari Mohd Yamin
Summary: In this study, a cationic complex of iridium(III) was synthesized and characterized using various spectroscopic techniques. The complex exhibited blue emission in the visible range, with emission spectra showing blue-shifted or red-shifted peaks under different conditions.
INDONESIAN JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Physical
Is Fatimah, Gani Purwiandono, Arif Hidayat, Suresh Sagadevan, Azlan Kamari
Summary: A magnetically separable nanocomposite of gamma-Fe2O3/montmorillonite (gamma-Fe2O3/Mt) with high photocatalytic activity for rhodamine B photodegradation has been successfully synthesized. The nanocomposite consists of uniformly dispersed gamma-Fe2O3 nanoparticles in a montmorillonite structure, and its degradation mechanism involves a significant contribution of the adsorption mechanism. The nanocomposite can be easily separated and reused due to its magnetism, without any chemical change even after repeated cycles.
CHEMICAL PHYSICS LETTERS
(2022)
Article
Polymer Science
Siew Tin Susana Wong, Azlan Kamari, Siti Najiah Mohd Yusoff, Mohd Zobir Hussein, Hidayatulfathi Othman, Noorshida Mohd Ali, Esther Phillip
Summary: The efficacy of GG-GO-Fe3O4 and PEC-GO-Fe3O4 nanocomposites as nanocarriers for controlling Aedes aegypti larvae with permethrin was investigated in this study. The physicochemical properties of the nanocomposites and their ability to load and release permethrin were analyzed. The results showed successful encapsulation of permethrin into the nanocarriers and prolonged release of permethrin for up to 16 hours. The release profiles of permethrin in rainwater were best described by the Korsmeyer-Peppas kinetic model.
Article
Materials Science, Textiles
Azlan Kamari, Siti Najiah Mohd Yusoff, Siew Tin Susana Wong, Norjan Yusof, Hidayatulfathi Othman, Mohd Zobir Hussein, Esther Phillip
Summary: This study successfully applied poly(epsilon-caprolactone) lipid-core nanocapsules in mosquito-repellent spray formulations for various fabrics. The results showed that the nanocapsule formulations exhibited excellent resistance to washing and heating on cotton and polyester fabrics, without causing irritation to human skin. The treated fabrics demonstrated effective mosquito repellency, even after multiple cycles of washing and heating. The application of poly(epsilon-caprolactone) lipid-core nanocapsules shows promising potential for enhancing the longevity and effectiveness of insect repellents on functional textiles.
FIBERS AND POLYMERS
(2022)
Review
Engineering, Multidisciplinary
Juliana Jumadi, Azlan Kamari, Nurulsaidah Abdul Rahim, Norjan Yusof, Is Fatimah
Summary: Undoubtedly, industrial activities have contributed significantly to the global environmental problem through the production of a large amount of waste. The palm oil sector is a major source of severe water pollution concerns due to its water-intensive nature. Research focused on palm oil mill effluent (POME) treatment has increased significantly in recent years, indicating the growing concern about the issue. This mini review discusses various biological treatment techniques for POME remediation, highlighting the importance of synergistic effects in achieving high contaminant removal performance.
JURNAL TEKNOLOGI-SCIENCES & ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Gani Purwiandono, Is Fatimah, Imam Sahroni, Putwi Widya Citradewi, Azlan Kamari, Suresh Sagadevan, Won-Chun Oh, Ruey-an Doong
Summary: This study synthesized Fe3O4@SiO2 nanocomposite biogenic silica from Salacca zalacca leaf ash and investigated its application in the photo-Fenton-like degradation of dye waste. The nanocomposite exhibited excellent photocatalytic activity and reusability, leading to high degradation efficiency of dye waste and significant removal of batik wastewater.
GREEN PROCESSING AND SYNTHESIS
(2022)
Article
Chemistry, Physical
Sharifah Norain Mohd Sharif, Norhayati Hashim, Illyas Md Isa, Suriani Abu Bakar, Mohamad Idris Saidin, Mohamad Syahrizal Ahmad, Mazidah Mamat, Mohd Zobir Hussein, Rahadian Zainul, Azlan Kamari
Summary: The study suggests that using carboxymethyl cellulose as a coating agent can extend the release of imidacloprid, reducing environmental pollution caused by excessive pesticide usage. The synthesized ZHN-SDS-IC-CMC has strong hygroscopic and swelling characteristics which enable the formation of a gel layer to slow down the release of imidacloprid.
CHEMICAL PHYSICS IMPACT
(2021)
Article
Engineering, Multidisciplinary
Syafiqah Md Nadzir, Norjan Yusof, Norazela Nordin, Azlan Kamari, Mohd Zulkhairi Mohd Yusoff
Summary: Nitrogen stress condition is found to enhance lipid and carbohydrate synthesis in Tetradesmus obliquus, with the highest yields reaching 37% and 23% respectively. Early accumulation of carbohydrate was induced under nitrogen stress condition, but decreased as carbon switched to lipid production on day 4. The fatty acid profile under nitrogen stress condition consisted of 54% PUFA, 43% SFA, and 3% MUFA, making it suitable for use in cold countries according to biofuel standards.
JURNAL TEKNOLOGI-SCIENCES & ENGINEERING
(2021)
