Accumulation of murine amyloid-β mimics early Alzheimer’s disease

Amyloid-β efflux from the central nervous system into the plasma

(2014) Kaleigh Filisa Roberts et al.   ANNALS OF NEUROLOGY

Cerebral ABC Transporter-common Mechanisms May Modulate Neurodegenerative Diseases and Depression in Elderly Subjects

(2014) Jens Pahnke et al.   ARCHIVES OF MEDICAL RESEARCH

Knock-In of Human BACE1 Cleaves Murine APP and Reiterates Alzheimer-like Phenotypes

(2014) K. Pluci ska et al.   JOURNAL OF NEUROSCIENCE

Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary

(2014) Hans-Gert Bernstein et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Alzheimer’s and ABC transporters — new opportunities for diagnostics and treatment

(2014) Jens Pahnke et al.   NEUROBIOLOGY OF DISEASE

Engineering Neprilysin Activity and Specificity to Create a Novel Therapeutic for Alzheimer’s Disease

(2014) Carl I. Webster et al.   PLoS One

Reduced Alzheimer’s Disease Pathology by St. John’s Wort Treatment is Independent of Hyperforin and Facilitated by ABCC1 and Microglia Activation in Mice

(2013) Jacqueline Hofrichter et al.   Current Alzheimer Research

Deletion of Abca7 Increases Cerebral Amyloid-  Accumulation in the J20 Mouse Model of Alzheimer's Disease

(2013) W. S. Kim et al.   JOURNAL OF NEUROSCIENCE

Impaired mitochondrial energy production and ABC transporter function—A crucial interconnection in dementing proteopathies of the brain

(2013) Jens Pahnke et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis

(2012) Katja Scheffler et al.   ACTA NEUROPATHOLOGICA

ABC Transporters B1, C1 and G2 Differentially Regulate Neuroregeneration in Mice

(2012) Toni Schumacher et al.   PLoS One

Determination of Spatial and Temporal Distribution of Microglia by 230nm-High-Resolution, High-Throughput Automated Analysis Reveals Different Amyloid Plaque Populations in an APP/PS1 Mouse Model of Alzheimers Disease

(2011) Katja Scheffler et al.   Current Alzheimer Research

Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice

(2011) Markus Krohn et al.   JOURNAL OF CLINICAL INVESTIGATION

Reduced Spine Density in Specific Regions of CA1 Pyramidal Neurons in Two Transgenic Mouse Models of Alzheimer's Disease

(2011) C. Perez-Cruz et al.   JOURNAL OF NEUROSCIENCE

Pathway-specific alteration of synaptic plasticity in Tg2576 mice

(2011) Jung Hoon Jung et al.   MOLECULES AND CELLS

Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression

(2011) Stefan J. Teipel et al.   PROGRESS IN NEUROBIOLOGY

Characterization of the 3xTg-AD mouse model of Alzheimer's disease: Part 1. Circadian changes

(2010) Roxanne Sterniczuk et al.   BRAIN RESEARCH

Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid-  in a Mouse Model of Alzheimer's Disease

(2010) A. M. S. Hartz et al.   MOLECULAR PHARMACOLOGY

New Function for an Old Enzyme: NEP Deficient Mice Develop Late-Onset Obesity

(2010) Matthias Becker et al.   PLoS One

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Alzheimer's disease and blood–brain barrier function—Why have anti-β-amyloid therapies failed to prevent dementia progression?

(2009) Jens Pahnke et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Improved Learning and Memory in Aged Mice Deficient in Amyloid β-Degrading Neutral Endopeptidase

(2009) Thomas Walther et al.   PLoS One

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

The value of incomplete mouse models of Alzheimer’s disease

(2008) Rebecca Radde et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures

(2008) Ryan J. Horvath et al.   JOURNAL OF NEUROCHEMISTRY

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE