Identification of tetracycline combinations as EphB1 tyrosine kinase inhibitors for treatment of neuropathic pain

Eph receptor signalling: from catalytic to non-catalytic functions

(2019) Lung-Yu Liang et al.   ONCOGENE

A mutation of the human EPHB2 gene leads to a major platelet functional defect

(2018) Eliane Berrou et al.   BLOOD

Relative Binding Free Energy Calculations in Drug Discovery: Recent Advances and Practical Considerations

(2017) Zoe Cournia et al.   Journal of Chemical Information and Modeling

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

(2017) Kenji Hanamura et al.   PLOS BIOLOGY

Hydraulic Extrusion of the Spinal Cord and Isolation of Dorsal Root Ganglia in Rodents

(2017) Mette Richner et al.   Jove-Journal of Visualized Experiments

Neuropathic pain

(2017) Luana Colloca et al.   Nature Reviews Disease Primers

Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment

(2016) Roberta F. White et al.   CORTEX

Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3

(2016) Alvin Kung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of Minocycline on Lumbar Radicular Neuropathic Pain

(2015) Pascal Vanelderen et al.   ANESTHESIOLOGY

Targeting the Eph System with Peptides and Peptide Conjugates

(2015) Stefan Riedl et al.   CURRENT DRUG TARGETS

Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?

(2015) Dávid Bajusz et al.   Journal of Cheminformatics

Spinal ephrinB/EphB signalling contributed to remifentanil-induced hyperalgesia via NMDA receptor

(2014) W.S. Xia et al.   EUROPEAN JOURNAL OF PAIN

Completing the structural family portrait of the human EphB tyrosine kinase domains

(2014) Ross C. Overman et al.   PROTEIN SCIENCE

Ephrins and pain

(2013) Ioanna Vasileiou et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

An Overview of Animal Models of Pain: Disease Models and Outcome Measures

(2013) Nicholas S. Gregory et al.   JOURNAL OF PAIN

Ephrin–Eph signaling as a potential therapeutic target for the treatment of myocardial infarction

(2013) Wesley T. O’Neal et al.   MEDICAL HYPOTHESES

Involvement of EphB1 Receptors Signalling in Models of Inflammatory and Neuropathic Pain

(2013) Vincent Cibert-Goton et al.   PLoS One

Neuropathic and inflammatory pain are modulated by tuberoinfundibular peptide of 39 residues

(2013) E. L. Dimitrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minocycline selectively inhibits M1 polarization of microglia

(2013) K Kobayashi et al.   Cell Death & Disease

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Hyperalgesia by synaptic long-term potentiation (LTP): an update

(2011) Jürgen Sandkühler et al.   CURRENT OPINION IN PHARMACOLOGY

Cultural Transformation Needed to Solve Public Health Problem of Chronic Pain

(2011) Anita Slomski   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

EphB Controls NMDA Receptor Function and Synaptic Targeting in a Subunit-Specific Manner

(2011) M. J. Nolt et al.   JOURNAL OF NEUROSCIENCE

Ephrin reverse signaling in axon guidance and synaptogenesis

(2011) Nan-Jie Xu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Targeting Eph receptors with peptides and small molecules: Progress and challenges

(2011) Roberta Noberini et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Nociceptor-Expressed Ephrin-B2 Regulates Inflammatory and Neuropathic Pain

(2010) Jing Zhao et al.   Molecular Pain

Assessment of Cancer-Related Neuropathy and Neuropathic Pain

(2010) C. S. Cleeland et al.   ONCOLOGIST

The First National Pain Medicine Summit—Final Summary Report

(2010) Philipp M. Lippe et al.   PAIN MEDICINE

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

(2009) Kwok-On Lai et al.   CURRENT OPINION IN NEUROBIOLOGY

Induction of Synaptic Long-Term Potentiation After Opioid Withdrawal

(2009) R. Drdla et al.   SCIENCE

Upregulation and redistribution of ephrinB and EphB receptor in dorsal root ganglion and spinal dorsal horn neurons after peripheral nerve injury and dorsal rhizotomy

(2008) Xue-Jun Song et al.   EUROPEAN JOURNAL OF PAIN

EphB receptor signaling in mouse spinal cord contributes to physical dependence on morphine

(2008) Wen-Tao Liu et al.   FASEB JOURNAL

Targeted Mutation of EphB1 Receptor Prevents Development of Neuropathic Hyperalgesia and Physical Dependence on Morphine in Mice

(2008) Yuan Han et al.   Molecular Pain

Bidirectional modulation of synaptic functions by Eph/ephrin signaling

(2008) Rüdiger Klein   NATURE NEUROSCIENCE

EphrinB-EphB receptor signaling contributes to neuropathic pain by regulating neural excitability and spinal synaptic plasticity in rats

(2008) Xue-Jun Song et al.   PAIN

Activation of peripheral ephrinBs/EphBs signaling induces hyperalgesia through a MAPKs-mediated mechanism in mice

(2008) Jun-Li Cao et al.   PAIN

Protonate3D: Assignment of ionization states and hydrogen coordinates to macromolecular structures

(2008) Paul Labute   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS