Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development

Trajectory-based differential expression analysis for single-cell sequencing data

(2020) Koen Van den Berge et al.   Nature Communications

Single-cell transcription analysis of Plasmodium vivax blood-stage parasites identifies stage- and species-specific profiles of expression

(2020) Juliana M. Sà et al.   PLOS BIOLOGY

When Is a Plasmodium-Infected Mosquito an Infectious Mosquito?

(2020) Wouter Graumans et al.   TRENDS IN PARASITOLOGY

Multidose Priming and Delayed Boosting Improve PfSPZ Vaccine Efficacy against Heterologous P. falciparum Controlled Human Malaria Infection

(2020) Kirsten E Lyke et al.   CLINICAL INFECTIOUS DISEASES

RTS,S malaria vaccine pilots in three African countries

(2019) Paul Adepoju   LANCET

Plasmodium berghei sporozoite specific genes- PbS10 and PbS23/SSP3 are required for the development of exo-erythrocytic forms

(2019) Jyothi Togiri et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The molecular machinery of translational control in malaria parasites

(2019) Sandra Bennink et al.   MOLECULAR MICROBIOLOGY

The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle

(2019) Virginia M. Howick et al.   SCIENCE

Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage

(2019) Rebecca R. Stanway et al.   CELL

Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

(2019) Scott E. Lindner et al.   Nature Communications

Protein–RNA interactions important for Plasmodium transmission

(2019) Kelly T. Rios et al.   PLoS Pathogens

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

(2018) Kelly Street et al.   BMC GENOMICS

Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development

(2018) Heather J. Painter et al.   Nature Communications

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites

(2018) Adam J Reid et al.   eLife

Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence

(2018) G. Costa et al.   Nature Communications

Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum

(2017) Heather J. Painter et al.   GENOME RESEARCH

Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial

(2017) Mahamadou S Sissoko et al.   LANCET INFECTIOUS DISEASES

New developments in anti-malarial target candidate and product profiles

(2017) Jeremy N. Burrows et al.   MALARIA JOURNAL

Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites

(2017) Asaf Poran et al.   NATURE

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

(2017) Armiyaw S. Nasamu et al.   SCIENCE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

A novel FIKK kinase regulates the development of mosquito and liver stages of the malaria

(2016) Dabbu Kumar Jaijyan et al.   Scientific Reports

UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

(2016) Min Zhang et al.   PLoS Pathogens

Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole

(2016) Aurélie Fougère et al.   PLoS Pathogens

Translational regulation in blood stages of the malaria parasite Plasmodium spp. : systems-wide studies pave the way

(2016) Shruthi Sridhar Vembar et al.   Wiley Interdisciplinary Reviews-RNA

A Genome-Scale Vector Resource Enables High-Throughput Reverse Genetic Screening in a Malaria Parasite

(2015) Ana Rita Gomes et al.   Cell Host & Microbe

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

(2015) S. Bhatt et al.   NATURE

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Malaria medicines: a glass half full?

(2015) Timothy N. C. Wells et al.   NATURE REVIEWS DRUG DISCOVERY

Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition

(2015) Christine S Hopp et al.   eLife

Translational regulation during stage transitions in malaria parasites

(2014) Liwang Cui et al.   Annals of the New York Academy of Sciences

SSP3 Is a Novel Plasmodium yoelii Sporozoite Surface Protein with a Role in Gliding Motility

(2014) Anke Harupa et al.   INFECTION AND IMMUNITY

Prevention measures and socio-economic development result in a decrease in malaria in Hainan, China

(2014) Shan-Qing Wang et al.   MALARIA JOURNAL

Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes

(2014) D. E. Neafsey et al.   SCIENCE

A Cysteine Protease Inhibitor of Plasmodium berghei Is Essential for Exo-erythrocytic Development

(2014) Christine Lehmann et al.   PLoS Pathogens

Plasmodium berghei Sporozoites Acquire Virulence and Immunogenicity during Mosquito Hemocoel Transit

(2013) Yuko Sato et al.   INFECTION AND IMMUNITY

Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis

(2013) Lucy S Tusting et al.   LANCET

Socioeconomic development to fight malaria, and beyond

(2013) Jürg Utzinger et al.   LANCET

Inhibitor of Cysteine Proteases Is Critical for Motility and Infectivity of Plasmodium Sporozoites

(2013) K. E. Boysen et al.   mBio

The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host

(2011) Alida Coppi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasmodium Cysteine Repeat Modular Proteins 3 and 4 are essential for malaria parasite transmission from the mosquito to the host

(2011) Bruno Douradinha et al.   MALARIA JOURNAL

PbGEST mediates malaria transmission to both mosquito and vertebrate host

(2011) Arthur M. Talman et al.   MOLECULAR MICROBIOLOGY

A Research Agenda for Malaria Eradication: Health Systems and Operational Research

(2011)   PLOS MEDICINE

A Research Agenda for Malaria Eradication: Vector Control

(2011)   PLOS MEDICINE

ThePlasmodiumeukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

(2010) Min Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages

(2010) Ahmed S. I. Aly et al.   MOLECULAR MICROBIOLOGY

Disruption ofPlasmodiumSporozoite Transmission by Depletion of Sporozoite Invasion-Associated Protein 1

(2009) Sabine Engelmann et al.   EUKARYOTIC CELL

TREP, a novel protein necessary for gliding motility of the malaria sporozoite

(2008) Audrey Combe et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Distinct Malaria Parasite Sporozoites Reveal Transcriptional Changes That Cause Differential Tissue Infection Competence in the Mosquito Vector and Mammalian Host

(2008) S. A. Mikolajczak et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeted deletion ofSAP1abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

(2008) Ahmed S. I. Aly et al.   MOLECULAR MICROBIOLOGY