Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice

Brown adipose tissue is associated with cardiometabolic health

(2021) Tobias Becher et al.   NATURE MEDICINE

Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity

(2020) Alana E. O’Mara et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical approach to the inflammatory etiology of cardiovascular diseases

(2020) Massimiliano Ruscica et al.   PHARMACOLOGICAL RESEARCH

LEPTIN, RESISTIN, AND PCSK9 – THE ROLE OF STAT3

(2020) Chiara Macchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Electrical Neurostimulation Promotes Brown Adipose Tissue Thermogenesis

(2020) Zhuang Li et al.   Frontiers in Endocrinology

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

(2019) Jane Armitage et al.   LANCET

The Impact of the Adipose Organ Plasticity on Inflammation and Cancer Progression

(2019) Corrêa et al.   Cells

Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development

(2019) Enchen Zhou et al.   CARDIOVASCULAR RESEARCH

Correlation of Brown Adipose Tissue with Other Body Fat Compartments and Patient Characteristics

(2018) Cornelia Brendle et al.   ACADEMIC RADIOLOGY

Present therapeutic role of cholesteryl ester transfer protein inhibitors

(2018) Nicola Ferri et al.   PHARMACOLOGICAL RESEARCH

The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice

(2017) Christine Landlinger et al.   EUROPEAN HEART JOURNAL

Effects of PCSK9 Inhibitors on Other than Low-Density Lipoprotein Cholesterol Lipid Variables

(2017) Theodosios D. Filippatos et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

(2017) Alexander Bartelt et al.   Nature Communications

Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease

(2016) Børge G. Nordestgaard   CIRCULATION RESEARCH

Role of Brown Fat in Lipoprotein Metabolism and Atherosclerosis

(2016) Geerte Hoeke et al.   CIRCULATION RESEARCH

Supraclavicular Brown Adipose Tissue 18F-FDG Uptake and Cardiovascular Disease

(2016) R. A. P. Takx et al.   JOURNAL OF NUCLEAR MEDICINE

Interpretation of the evidence for the efficacy and safety of statin therapy

(2016) Rory Collins et al.   LANCET

Selective Impairment of Glucose but Not Fatty Acid or Oxidative Metabolism in Brown Adipose Tissue of Subjects With Type 2 Diabetes

(2015) Denis P. Blondin et al.   DIABETES

In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis

(2015) Sébastien M. Labbé et al.   FASEB JOURNAL

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

(2015) Labros Sidossis et al.   JOURNAL OF CLINICAL INVESTIGATION

PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial

(2015) Frederick J Raal et al.   LANCET

Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events

(2015) Jennifer G. Robinson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

(2015) Jimmy F. P. Berbée et al.   Nature Communications

Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance

(2015) Anne-Laure Poher et al.   Frontiers in Physiology

Thermogenic brown and beige/brite adipogenesis in humans

(2014) Rubén Cereijo et al.   ANNALS OF MEDICINE

Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin

(2014) Susan Kühnast et al.   JOURNAL OF LIPID RESEARCH

Brown adipose tissue takes up plasma triglycerides mostly after lipolysis

(2014) P. Padmini S. J. Khedoe et al.   JOURNAL OF LIPID RESEARCH

Anti-PCSK9 Monotherapy for Hypercholesterolemia

(2014) Michael J. Koren et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A 52-Week Placebo-Controlled Trial of Evolocumab in Hyperlipidemia

(2014) Dirk J. Blom et al.   NEW ENGLAND JOURNAL OF MEDICINE

HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events

(2014) Anand Rohatgi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold Exposure Promotes Atherosclerotic Plaque Growth and Instability via UCP1-Dependent Lipolysis

(2013) Mei Dong et al.   Cell Metabolism

White, Brown, Beige/Brite: Different Adipose Cells for Different Functions?

(2013) Marta Giralt et al.   ENDOCRINOLOGY

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans

(2012) Véronique Ouellet et al.   JOURNAL OF CLINICAL INVESTIGATION

The Controversies of Statin Therapy

(2012) J. Wouter Jukema et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice

(2011) Man C. Wong et al.   ATHEROSCLEROSIS

Prolonged Caloric Restriction in Obese Patients With Type 2 Diabetes Mellitus Decreases Plasma CETP and Increases Apolipoprotein AI Levels Without Improving the Cholesterol Efflux Properties of HDL

(2011) Y. Wang et al.   DIABETES CARE

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lipoprotein Particle Size and Concentration by Nuclear Magnetic Resonance and Incident Type 2 Diabetes in Women

(2010) S. Mora et al.   DIABETES

Lipoprotein Particle Profiles by Nuclear Magnetic Resonance Compared With Standard Lipids and Apolipoproteins in Predicting Incident Cardiovascular Disease in Women

(2009) Samia Mora et al.   CIRCULATION