The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions

Targeting the functional interplay between endoplasmic reticulum oxidoreductin-1α and protein disulfide isomerase suppresses the progression of cervical cancer

(2019) Yini Zhang et al.   EBioMedicine

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss

(2018) Diego Pozzer et al.   Redox Biology

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level

(2016) Tsutomu Tanaka et al.   BRITISH JOURNAL OF CANCER

The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts

(2016) Louis Dore-Savard et al.   Scientific Reports

ERO1: A protein disulfide oxidase and H2O2 producer

(2015) Ester Zito   FREE RADICAL BIOLOGY AND MEDICINE

ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis

(2015) Souvik Dey et al.   JOURNAL OF CLINICAL INVESTIGATION

A New Surface Plasmon Resonance-Based Immunoassay for Rapid, Reproducible and Sensitive Quantification of Pentraxin-3 in Human Plasma

(2014) Mara Canovi et al.   SENSORS

Origins of Metastatic Traits

(2013) Sakari Vanharanta et al.   CANCER CELL

VEGFA and tumour angiogenesis

(2013) L. Claesson-Welsh et al.   JOURNAL OF INTERNAL MEDICINE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

PRDX4, an Endoplasmic Reticulum-Localized Peroxiredoxin at the Crossroads Between Enzymatic Oxidative Protein Folding and Nonenzymatic Protein Oxidation

(2012) Ester Zito   ANTIOXIDANTS & REDOX SIGNALING

Anti-VEGF/VEGFR Therapy for Cancer: Reassessing the Target

(2012) B. Sitohy et al.   CANCER RESEARCH

The Unfolded Protein Response Induces the Angiogenic Switch in Human Tumor Cells through the PERK/ATF4 Pathway

(2012) Y. Wang et al.   CANCER RESEARCH

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Vitamin K epoxide reductase contributes to protein disulfide formation and redox homeostasis within the endoplasmic reticulum

(2012) Lori A. Rutkevich et al.   MOLECULAR BIOLOGY OF THE CELL

Endoplasmic Reticulum Thiol Oxidase Deficiency Leads to Ascorbic Acid Depletion and Noncanonical Scurvy in Mice

(2012) Ester Zito et al.   MOLECULAR CELL

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Total Chemical Synthesis of Biologically Active Vascular Endothelial Growth Factor

(2011) Kalyaneswar Mandal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load

(2011) King-Tung Chin et al.   FASEB JOURNAL

Tying the knot: The cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines

(2011) Shalini Iyer et al.   FEBS Journal

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

(2011) C. C.-L. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Guidelines for the welfare and use of animals in cancer research

(2010) P Workman et al.   BRITISH JOURNAL OF CANCER

A Small Molecule Inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with Selectively Reversible Thiol Reactivity

(2010) Jaime D. Blais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

(2010) Ester Zito et al.   JOURNAL OF CELL BIOLOGY

Oxidative Protein Folding by an Endoplasmic Reticulum-Localized Peroxiredoxin

(2010) Ester Zito et al.   MOLECULAR CELL

Development of a Preclinical Model of Spontaneous Human Melanoma Central Nervous System Metastasis

(2008) W. Cruz-Munoz et al.   CANCER RESEARCH