Guidelines for the welfare and use of animals in cancer research

Patient-Derived First Generation Xenografts of Non-Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy

(2010) X. Dong et al.   CLINICAL CANCER RESEARCH

Plasma Protein Binding in Drug Discovery and Development

(2010) Monique Howard et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Integrative Analysis of Proteomic Signatures, Mutations, and Drug Responsiveness in the NCI 60 Cancer Cell Line Set

(2010) E. S. Park et al.   MOLECULAR CANCER THERAPEUTICS

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

Journal Editorial Policies, Animal Welfare, and the 3Rs

(2009) Nicola J. Osborne et al.   AMERICAN JOURNAL OF BIOETHICS

Flavones as Colorectal Cancer Chemopreventive Agents--Phenol-O-Methylation Enhances Efficacy

(2009) H. Cai et al.   Cancer Prevention Research

Activation of the PI3K/AKT Pathway Induces Urothelial Carcinoma of the Renal Pelvis: Identification in Human Tumors and Confirmation in Animal Models

(2009) C.-N. Qian et al.   CANCER RESEARCH

MK2 regulates the early stages of skin tumor promotion

(2009) Claus Johansen et al.   CARCINOGENESIS

Intravital microscopy of tumor angiogenesis and regression in the dorsal skin fold chamber: mechanistic insights and preclinical testing of therapeutic strategies

(2009) Gudrun E. Koehl et al.   CLINICAL & EXPERIMENTAL METASTASIS

Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma

(2009) K. Politi et al.   Disease Models & Mechanisms

Multimodality imaging of TGFβ signaling in breast cancer metastases

(2009) Inna Serganova et al.   FASEB JOURNAL

Molecular Imaging of Pancreatic Cancer in an Animal Model Using Targeted Multifunctional Nanoparticles

(2009) Lily Yang et al.   GASTROENTEROLOGY

Mouse models of human AML accurately predict chemotherapy response

(2009) J. Zuber et al.   GENES & DEVELOPMENT

Oral Administration of 3,3′-Diindolylmethane Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells in BALB/c Mice

(2009) Eun Ji Kim et al.   JOURNAL OF NUTRITION

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death

(2009) D A Tennant et al.   ONCOGENE

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide

(2009) Q.-D. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting Strain-Related Differences in Radiation Sensitivity of the Mouse Lung: Recognizing and Avoiding the Confounding Effects of Pleural Effusions

(2009) Isabel L. Jackson et al.   RADIATION RESEARCH

Urinary Retention and Cystitis Associated with Subcutaneous Estradiol Pellets in Female Nude Mice

(2009) Gail Pearse et al.   TOXICOLOGIC PATHOLOGY

High throughput solubility determination with application to selection of compounds for fragment screening

(2008) Nicola Colclough et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Analgesia from a veterinary perspective

(2008) P. Flecknell   BRITISH JOURNAL OF ANAESTHESIA

Interactions between microenvironment and cancer cells in two animal models of bone metastasis

(2008) S Blouin et al.   BRITISH JOURNAL OF CANCER

Imaging Pharmacodynamics of the  -Folate Receptor-Targeted Thymidylate Synthase Inhibitor BGC 945

(2008) R. G. Pillai et al.   CANCER RESEARCH

Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance

(2008) N. T. Ihle et al.   CANCER RESEARCH

Molecular Characterization of the Pediatric Preclinical Testing Panel

(2008) G. Neale et al.   CLINICAL CANCER RESEARCH

Direct In Vivo Xenograft Tumor Model for Predicting Chemotherapeutic Drug Response in Cancer Patients

(2008) B Rubio-Viqueira et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Targeted therapeutics for cancer treatment: major progress towards personalised molecular medicine

(2008) Paul Workman et al.   CURRENT OPINION IN PHARMACOLOGY

Modeling therapy resistance in genetically engineered mouse cancer models

(2008) S ROTTENBERG et al.   DRUG RESISTANCE UPDATES

Application of dried blood spots combined with HPLC-MS/MS for the quantification of acetaminophen in toxicokinetic studies

(2008) Matt Barfield et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Imaging of186Re-liposome therapy in ovarian cancer xenograft model of peritoneal carcinomatosis

(2008) Cristina L. Zavaleta et al.   JOURNAL OF DRUG TARGETING

Mouse Modifier Genes in Mammary Tumorigenesis and Metastasis

(2008) Scott F. Winter et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Signal Transduction in Transgenic Mouse Models of Human Breast Cancer—Implications for Human Breast Cancer

(2008) Richard Marcotte et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

(2008) Birk Poller et al.   JOURNAL OF NEUROCHEMISTRY

A novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells

(2008) Brian T. Ragel et al.   JOURNAL OF NEUROSURGERY

Calculation of Molecular Lipophilicity: State-of-the-Art and Comparison of LogP Methods on more than 96,000 Compounds

(2008) Raimund Mannhold et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Estimation of Apparent Tumor Vascular Permeability from Multiphoton Fluorescence Microscopic Images of P22 Rat Sarcomas In Vivo

(2008) Constantino Carlos Reyes-Aldasoro et al.   MICROCIRCULATION

Modelling Myc inhibition as a cancer therapy

(2008) Laura Soucek et al.   NATURE

Imaging in the era of molecular oncology

(2008) Ralph Weissleder et al.   NATURE

Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy

(2008) Corey M. McCann et al.   NEUROIMAGE

Computational aqueous solubility prediction for drug-like compounds in congeneric series

(2007) Lei Du-Cuny et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY