Co-Chaperone Bag-1 Plays a Role in the Autophagy-Dependent Cell Survival through Beclin 1 Interaction

A BAG's life: Every connection matters in cancer

(2020) Elena Mariotto et al.   PHARMACOLOGY & THERAPEUTICS

Microautophagy – distinct molecular mechanisms handle cargoes of many sizes

(2020) Sebastian Schuck   JOURNAL OF CELL SCIENCE

Bag-1 silencing enhanced chemotherapeutic drug-induced apoptosis in MCF-7 breast cancer cells affecting PI3K/Akt/mTOR and MAPK signaling pathways

(2019) Pelin Ozfiliz Kilbas et al.   MOLECULAR BIOLOGY REPORTS

A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin

(2019) Matthew G. Costales et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bag-1 stimulates Bad phosphorylation through activation of Akt and Raf kinases to mediate cell survival in breast cancer

(2019) Tugba Kizilboga et al.   BMC CANCER

Bcl‑2 promotes metastasis through the epithelial‑to‑mesenchymal transition in the BCap37 medullary breast cancer cell line

(2018) Chengyong Du et al.   Oncology Letters

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

(2018) H. Furkan Alkan et al.   Cell Metabolism

Molecular switching from ubiquitin-proteasome to autophagy pathways in mice stroke model

(2018) Xia Liu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

VPS34 complexes from a structural perspective

(2018) Yohei Ohashi et al.   JOURNAL OF LIPID RESEARCH

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

(2017) Hayden Weng Siong Tan et al.   Nature Communications

The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease

(2017) Elisabeth Stürner et al.   Frontiers in Molecular Neuroscience

Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy

(2017) Fei Xu et al.   Scientific Reports

Divergent roles of BECN1 in LC3 lipidation and autophagosomal function

(2015) Ruina He et al.   Autophagy

BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism

(2015) Andrea E. Rodríguez et al.   Autophagy

Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells

(2015) Pelin Ozfiliz et al.   CELL BIOCHEMISTRY AND FUNCTION

Autophagy signal transduction by ATG proteins: from hierarchies to networks

(2015) Sebastian Wesselborg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

l-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells

(2014) Yuhua Zhu et al.   AMINO ACIDS

Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

(2014) Yongjie Wei et al.   Autophagy

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta

(2014) Melania Minoia et al.   Autophagy

Autophagy and human disease: emerging themes

(2014) Jaime L Schneider et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation

(2014) Rui Chen et al.   JOURNAL OF CELL BIOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

(2012) Jean-Paul Decuypere et al.   Cells

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

BAG3 and friends: Co-chaperones in selective autophagy during aging and disease

(2011) Christian Behl   Autophagy

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy

(2011) S. Lee et al.   JOURNAL OF NEUROSCIENCE

BAG1: The Guardian of Anti-Apoptotic Proteins in Acute Myeloid Leukemia

(2011) Sanja Aveic et al.   PLoS One

Different BAG-1 isoforms have distinct functions in modulating chemotherapeutic-induced apoptosis in breast cancer cells

(2009) Hong-yu Liu et al.   ACTA PHARMACOLOGICA SINICA

Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL

(2009) Einat Zalckvar et al.   Autophagy

Inhibition of lysosomal functions reduces proteasomal activity

(2009) Liyan Qiao et al.   NEUROSCIENCE LETTERS

RNAi in Budding Yeast

(2009) I. A. Drinnenberg et al.   SCIENCE

The BAG proteins: a ubiquitous family of chaperone regulators

(2008) M. Kabbage et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cardioprotection by adaptation to ischaemia augments autophagy in association with BAG-1 protein

(2008) Narasimman Gurusamy et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Bacterial expression and purification of Interleukin-2 Tyrosine kinase: Single step separation of the chaperonin impurity

(2008) Raji E. Joseph et al.   PROTEIN EXPRESSION AND PURIFICATION