Kaempferol attenuates streptozotocin-induced diabetic nephropathy by downregulating TRAF6 expression: The role of TRAF6 in diabetic nephropathy

Phytochemistry, pharmacological activities and uses of traditional medicinal plant Kaempferia galanga L. – An overview

(2020) Ajay Kumar   JOURNAL OF ETHNOPHARMACOLOGY

An anti-inflammatory chalcone derivative prevents heart and kidney from hyperlipidemia-induced injuries by attenuating inflammation

(2018) Xiong Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanistic insights into the augmented effect of bone marrow mesenchymal stem cells and thiazolidinediones in streptozotocin-nicotinamide induced diabetic rats

(2018) Alaaeldin Ahmed Hamza et al.   Scientific Reports

The Flavonoid Kaempferol Ameliorates Streptozotocin-Induced Diabetes by Suppressing Hepatic Glucose Production

(2018) Hana Alkhalidy et al.   MOLECULES

Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells

(2018) Tae Woo Kim et al.   Cell Death & Disease

Ellagic acid attenuates streptozocin induced diabetic nephropathy via the regulation of oxidative stress and inflammatory signaling

(2018) Benhong Zhou et al.   FOOD AND CHEMICAL TOXICOLOGY

Toll-like receptor-4 signaling mediates inflammation and tissue injury in diabetic nephropathy

(2017) Giacomo Garibotto et al.   JOURNAL OF NEPHROLOGY

Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/mTOR signaling pathway

(2017) Ritu Varshney et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Kaempferol Attenuates Cardiac Hypertrophy via Regulation of ASK1/MAPK Signaling Pathway and Oxidative Stress

(2017) Hong Feng et al.   PLANTA MEDICA

Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes

(2016) Theodora Szasz et al.   DIABETES

Protective effects of kaempferol against reactive oxygen species-induced hemolysis and its antiproliferative activity on human cancer cells

(2016) Wenzhen Liao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Extraction, characterization and evaluation of Kaempferia galanga L. (Zingiberaceae) rhizome extracts against acute and chronic inflammation in rats

(2016) Puralae Channabasavaiah Jagadish et al.   JOURNAL OF ETHNOPHARMACOLOGY

Association of polymorphisms in the MyD88, IRAK4 and TRAF6 genes and susceptibility to type 2 diabetes mellitus and diabetic nephropathy in a southern Han Chinese population

(2016) Congcong Guo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Kaempferol alleviates insulin resistance via hepatic IKK/NF-κB signal in type 2 diabetic rats

(2015) Cheng Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Altered immunometabolism at the interface of increased endoplasmic reticulum (ER) stress in patients with type 2 diabetes

(2015) R. Lenin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice

(2015) Yanqing Zang et al.   Food & Function

Expression and cellular distribution of TLR4, MyD88, and NF-κB in diabetic renal tubulointerstitial fibrosis, in vitro and in vivo

(2014) Ping Liu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Global toll-like receptor 4 knockout results in decreased renal inflammation, fibrosis and podocytopathy

(2014) Ishwarlal Jialal et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

miR-21 overexpression enhances TGF-β1-induced epithelial-to-mesenchymal transition by target smad7 and aggravates renal damage in diabetic nephropathy

(2014) Jin-Yang Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Insulin infusion suppresses while glucose infusion induces Toll-like receptors and high-mobility group-B1 protein expression in mononuclear cells of type 1 diabetes patients

(2013) Paresh Dandona et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pathophysiological mechanisms involving aggressive islet cell destruction in fulminant type 1 diabetes [Review]

(2013) Shoichiro Tanaka et al.   ENDOCRINE JOURNAL

Comparison of the transduction efficiency of tyrosine-mutant adeno-associated virus serotype vectors in kidney

(2012) Yan F. Qi et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Inflammation in Diabetic Nephropathy

(2012) Andy K. H. Lim et al.   MEDIATORS OF INFLAMMATION

Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation

(2012) J. M. Reynolds et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flavonol kaempferol improves chronic hyperglycemia-impaired pancreatic beta-cell viability and insulin secretory function

(2011) Yanling Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Toll-Like Receptor 4 Promotes Tubular Inflammation in Diabetic Nephropathy

(2011) M. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology