MFG-E8 attenuates inflammation in subarachnoid hemorrhage by driving microglial M2 polarization

Cerebroprotection by salvianolic acid B after experimental subarachnoid hemorrhage occurs via Nrf2- and SIRT1-dependent pathways

(2018) Xiangsheng Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Peroxiredoxin 2 activates microglia by interacting with Toll-like receptor 4 after subarachnoid hemorrhage

(2018) Yue Lu et al.   Journal of Neuroinflammation

Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats

(2018) Zhiyi Xie et al.   NEUROPHARMACOLOGY

Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll-like receptor 4 signaling pathway

(2018) Xiangsheng Zhang et al.   FASEB JOURNAL

TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway

(2018) Ran Li et al.   Journal of Neuroinflammation

Microglial signatures and their role in health and disease

(2018) Oleg Butovsky et al.   NATURE REVIEWS NEUROSCIENCE

Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury

(2018) Yong-Yue Gao et al.   Cell Death & Disease

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

(2018) Marija Kojic et al.   Nature Communications

Peroxiredoxin 1/2 protects brain against H2O2-induced apoptosis after subarachnoid hemorrhage

(2018) Yue Lu et al.   FASEB JOURNAL

Cerebral ischemic damage in diabetes: an inflammatory perspective

(2017) Vibha Shukla et al.   Journal of Neuroinflammation

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Modulators of microglial activation and polarization after intracerebral haemorrhage

(2017) Xi Lan et al.   Nature Reviews Neurology

Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson’s Disease

(2017) Sudhakar R. Subramaniam et al.   Frontiers in Aging Neuroscience

Roles of Pannexin-1 Channels in Inflammatory Response through the TLRs/NF-Kappa B Signaling Pathway Following Experimental Subarachnoid Hemorrhage in Rats

(2017) Ling-Yun Wu et al.   Frontiers in Molecular Neuroscience

Neuronal Soluble Fas Ligand Drives M1-Microglia Polarization after Cerebral Ischemia

(2016) Hai-Lan Meng et al.   CNS Neuroscience & Therapeutics

Tetrahydrocurcumin provides neuroprotection in rats after traumatic brain injury: autophagy and the PI3K/AKT pathways as a potential mechanism

(2016) Yongyue Gao et al.   JOURNAL OF SURGICAL RESEARCH

MFG-E8 Selectively Inhibited Aβ-Induced Microglial M1 Polarization via NF-κB and PI3K-Akt Pathways

(2016) Xiaolei Shi et al.   MOLECULAR NEUROBIOLOGY

The emerging role of signal transducer and activator of transcription 3 in cerebral ischemic and hemorrhagic stroke

(2016) Zhenxing Liang et al.   PROGRESS IN NEUROBIOLOGY

Dissociation of Early and Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage

(2016) Oliver G.S. Ayling et al.   STROKE

Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment

(2015) Chenhui Zhou et al.   Journal of Neuroinflammation

Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner

(2015) Jie Pan et al.   Journal of Neuroinflammation

Polarization of Prostate Cancer-associated Macrophages Is Induced by Milk Fat Globule-EGF Factor 8 (MFG-E8)-mediated Efferocytosis

(2014) Fabiana N. Soki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early release of high-mobility group box 1 (HMGB1) from neurons in experimental subarachnoid hemorrhage in vivo and in vitro

(2014) Qing Sun et al.   Journal of Neuroinflammation

Recombinant Milk Fat Globule–EGF Factor-8 Reduces Oxidative Stress via Integrin β3/Nuclear Factor Erythroid 2–Related Factor 2/Heme Oxygenase Pathway in Subarachnoid Hemorrhage Rats

(2014) Fei Liu et al.   STROKE

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

(2013) Nicolas Deroide et al.   JOURNAL OF CLINICAL INVESTIGATION

Survivin Is a Transcriptional Target of STAT3 Critical to Estradiol Neuroprotection in Global Ischemia

(2013) Y. Sehara et al.   JOURNAL OF NEUROSCIENCE

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

(2012) Joana C d’Avila et al.   Journal of Neuroinflammation

The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity

(2012) Endong Li et al.   Journal of Neuroinflammation

MFG-E8 Released by Apoptotic Endothelial Cells Triggers Anti-Inflammatory Macrophage Reprogramming

(2012) Marie-Joëlle Brissette et al.   PLoS One

Review: milk fat globule-EGF factor 8 expression, function and plausible signal transduction in resolving inflammation

(2011) Monowar Aziz et al.   APOPTOSIS

Recombinant human MFG-E8 attenuates cerebral ischemic injury: Its role in anti-inflammation and anti-apoptosis

(2011) Cletus Cheyuo et al.   NEUROPHARMACOLOGY

Pre-Treatment of Recombinant Mouse MFG-E8 Downregulates LPS-Induced TNF-α Production in Macrophages via STAT3-Mediated SOCS3 Activation

(2011) Monowar Aziz et al.   PLoS One

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells

(2009) R. Behera et al.   CARCINOGENESIS

Subarachnoid Hemorrhage: Is It Time for a New Direction?

(2008) J. Cahill et al.   STROKE

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS