标题
Polygenic risk modeling with latent trait-related genetic components
作者
关键词
-
出版物
EUROPEAN JOURNAL OF HUMAN GENETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-02-09
DOI
10.1038/s41431-021-00813-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genetics of 35 blood and urine biomarkers in the UK Biobank
- (2021) Nasa Sinnott-Armstrong et al. NATURE GENETICS
- Assessing Digital Phenotyping to Enhance Genetic Studies of Human Diseases
- (2020) Christopher DeBoever et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Non-parametric Polygenic Risk Prediction via Partitioned GWAS Summary Statistics
- (2020) Sung Chun et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank
- (2020) Junyang Qian et al. PLoS Genetics
- LDpred2: better, faster, stronger
- (2020) Florian Privé et al. BIOINFORMATICS
- WikiPathways: connecting communities
- (2020) Marvin Martens et al. NUCLEIC ACIDS RESEARCH
- Whole Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized with Early-Onset Myocardial Infarction
- (2019) Amit V. Khera et al. CIRCULATION
- SLC22A3 is associated with lipoprotein (a) concentration and cardiovascular disease in familial hypercholesterolemia
- (2019) Martine Paquette et al. CLINICAL BIOCHEMISTRY
- Polygenic prediction via Bayesian regression and continuous shrinkage priors
- (2019) Tian Ge et al. Nature Communications
- Reverse GWAS: Using genetics to identify and model phenotypic subtypes
- (2019) Andy Dahl et al. PLoS Genetics
- Phenome-wide Burden of Copy-Number Variation in the UK Biobank
- (2019) Matthew Aguirre et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology
- (2019) Yosuke Tanigawa et al. Nature Communications
- Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2
- (2019) Ana I. Hernandez Cordero et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative
- (2018) Lars G. Fritsche et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr
- (2018) Florian Privé et al. BIOINFORMATICS
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
- (2018) Hilary K. Finucane et al. NATURE GENETICS
- Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study
- (2018) Christopher DeBoever et al. Nature Communications
- Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
- (2018) Angli Xue et al. Nature Communications
- Leveraging Polygenic Functional Enrichment to Improve GWAS Power
- (2018) Gleb Kichaev et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
- (2018) Spencer L James et al. LANCET
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci
- (2017) Amy V. Jones et al. HUMAN MOLECULAR GENETICS
- Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores
- (2016) Kristi Läll et al. GENETICS IN MEDICINE
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
- (2015) Bjarni J. Vilhjálmsson et al. AMERICAN JOURNAL OF HUMAN GENETICS
- New genetic loci link adipose and insulin biology to body fat distribution
- (2015) Dmitry Shungin et al. NATURE
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- Efficient Bayesian mixed-model analysis increases association power in large cohorts
- (2015) Po-Ru Loh et al. NATURE GENETICS
- FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
- (2015) Melina Claussnitzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- PRSice: Polygenic Risk Score software
- (2014) Jack Euesden et al. BIOINFORMATICS
- Finding Structure with Randomness: Probabilistic Algorithms for Constructing Approximate Matrix Decompositions
- (2011) N. Halko et al. SIAM REVIEW
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
- (2009) Sekar Kathiresan et al. NATURE GENETICS
- The Murine Stanniocalcin 2 Gene Is a Negative Regulator of Postnatal Growth
- (2008) Andy C.-M. Chang et al. ENDOCRINOLOGY
- Genome-wide association analysis identifies 20 loci that influence adult height
- (2008) Michael N Weedon et al. NATURE GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More