Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology
出版年份 2019 全文链接
标题
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-06
DOI
10.1038/s41467-019-11953-9
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease
- (2018) Noura S. Abul-Husn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study
- (2018) Christopher DeBoever et al. Nature Communications
- Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease
- (2018) Connor A. Emdin et al. Nature Communications
- Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry
- (2018) Loic Yengo et al. HUMAN MOLECULAR GENETICS
- Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics
- (2018) Gregory McInnes et al. BIOINFORMATICS
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program
- (2018) Derek Klarin et al. NATURE GENETICS
- Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease
- (2017) Connor A. Emdin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Monosynaptic retrograde tracing of neurons expressing the G-protein coupled receptor Gpr151 in the mouse brain
- (2017) Jonas Broms et al. JOURNAL OF COMPARATIVE NEUROLOGY
- White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function
- (2017) Youn Wook Chung et al. Scientific Reports
- A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
- (2016) Manuel A. Rivas et al. Nature Communications
- Body mass index and risk of non-melanoma skin cancer: cumulative evidence from prospective studies
- (2016) Daijun Zhou et al. Scientific Reports
- Gallstones
- (2016) Frank Lammert et al. Nature Reviews Disease Primers
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- Modeling transcriptional regulation
- (2015) NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
- (2015) Wesley K Kroeze et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A New Initiative on Precision Medicine
- (2015) Francis S. Collins et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury
- (2015) Youn Wook Chung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effect of predicted protein-truncating genetic variants on the human transcriptome
- (2015) M. A. Rivas et al. SCIENCE
- PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
- (2015) Wesley K Kroeze et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens
- (2015) Cynthia L Smith et al. Journal of Biomedical Semantics
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- The Global Burden of Ischemic Heart Disease in 1990 and 2010
- (2014) Andrew E. Moran et al. CIRCULATION
- A polygenic burden of rare disruptive mutations in schizophrenia
- (2014) Shaun M. Purcell et al. NATURE
- G Protein-Coupled Receptors and Adipogenesis: A Focus on Adenosine Receptors
- (2013) Anna Eisenstein et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Validating therapeutic targets through human genetics
- (2013) Robert M. Plenge et al. NATURE REVIEWS DRUG DISCOVERY
- The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
- (2013) Danielle Welter et al. NUCLEIC ACIDS RESEARCH
- Bioelectrical impedance analysis to estimate body composition in children and adolescents: a systematic review and evidence appraisal of validity, responsiveness, reliability and measurement error
- (2013) H. Talma et al. Obesity Reviews
- A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes
- (2012) D. G. MacArthur et al. SCIENCE
- New national Biobank of The Danish Center for Strategic Research on Type 2 Diabetes (DD2)
- (2012) Henry Christensen et al. Clinical Epidemiology
- Phytosterol and cholesterol precursor levels indicate increased cholesterol excretion and biosynthesis in gallstone disease
- (2011) Marcin Krawczyk et al. HEPATOLOGY
- China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up
- (2011) Z. Chen et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
- (2011) Manuel A Rivas et al. NATURE GENETICS
- Modernizing Reference Genome Assemblies
- (2011) Deanna M. Church et al. PLOS BIOLOGY
- GPR103b Functions in the Peripheral Regulation of Adipogenesis
- (2010) Mukandila Mulumba et al. MOLECULAR ENDOCRINOLOGY
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
- (2009) Shaun M. Purcell et al. NATURE
- Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes
- (2009) S. Nejentsev et al. SCIENCE
- Genes mirror geography within Europe
- (2008) John Novembre et al. NATURE
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