Monitoring mitochondrial translation in living cells

COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria

(2020) David Pacheu-Grau et al.   JOURNAL OF MOLECULAR BIOLOGY

Absolute yeast mitochondrial proteome quantification reveals trade-off between biosynthesis and energy generation during diauxic shift

(2020) Francesca Di Bartolomeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial protein biogenesis in the synapse is supported by local translation

(2020) Bozena Kuzniewska et al.   EMBO REPORTS

A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly

(2020) Michela Di Nottia et al.   NEUROBIOLOGY OF DISEASE

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

(2019) Jean-Michel Cioni et al.   CELL

Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas

(2019) Estela Area-Gomez et al.   JOURNAL OF CLINICAL INVESTIGATION

Transport of Proteins into Mitochondria

(2019) Katja G. Hansen et al.   PROTEIN JOURNAL

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments

(2019) Anne-Sophie Hafner et al.   SCIENCE

Coupling of import and assembly pathways in mitochondrial protein biogenesis

(2019) Alexander Grevel et al.   BIOLOGICAL CHEMISTRY

A Brief History of Mitochondrial Pathologies

(2019) Salvatore DiMauro   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase

(2019) Shivatheja Soma et al.   Cell Reports

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission

(2018) Sven Truckenbrodt et al.   EMBO JOURNAL

Human diseases associated with defects in assembly of OXPHOS complexes

(2018) Daniele Ghezzi et al.   Essays in Biochemistry

Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population

(2018) Evan Graehl Williams et al.   MOLECULAR & CELLULAR PROTEOMICS

In situimaging of mitochondrial translation shows weak correlation with nucleoid DNA intensity and no suppression during mitosis

(2017) Christopher Estell et al.   JOURNAL OF CELL SCIENCE

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture

(2017) Laura C. Graham et al.   Molecular Neurodegeneration

Mitochondrial diseases: the contribution of organelle stress responses to pathology

(2017) Anu Suomalainen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plasticity of Mitochondrial Translation

(2017) Sven Dennerlein et al.   TRENDS IN CELL BIOLOGY

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein

(2016) Ricarda Richter-Dennerlein et al.   CELL

Molecular-genetic characterization and rescue of a TSFM mutation causing childhood-onset ataxia and nonobstructive cardiomyopathy

(2016) Sonia Emperador et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

(2016) Heather L Smith et al.   eLife

Cooperation between COA6 and SCO2 in COX2 Maturation during Cytochrome c Oxidase Assembly Links Two Mitochondrial Cardiomyopathies

(2015) David Pacheu-Grau et al.   Cell Metabolism

COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2

(2015) David A. Stroud et al.   HUMAN MOLECULAR GENETICS

Mitochondrial transcript maturation and its disorders

(2015) Lindsey Van Haute et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Synaptic mitochondria: A brain mitochondria cluster with a specific proteome

(2015) Katalin Völgyi et al.   Journal of Proteomics

Integrating mitochondrial translation into the cellular context

(2015) Ricarda Richter-Dennerlein et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physiological and structural differences in spatially distinct subpopulations of cardiac mitochondria: influence of cardiac pathologies

(2014) John M. Hollander et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondria: Impaired mitochondrial translation in human disease

(2014) Veronika Boczonadi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial antibiograms in personalized medicine

(2012) D. Pacheu-Grau et al.   HUMAN MOLECULAR GENETICS

Synaptic Energy Use and Supply

(2012) Julia J. Harris et al.   NEURON

Mutations in C12orf65 in Patients with Encephalomyopathy and a Mitochondrial Translation Defect

(2010) Hana Antonicka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups

(2010) Aurora Gómez-Durán et al.   HUMAN MOLECULAR GENETICS

Mitochondrial Translation and Beyond: Processes Implicated in Combined Oxidative Phosphorylation Deficiencies

(2010) Paulien Smits et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons

(2010) Daniela C Dieterich et al.   NATURE NEUROSCIENCE

Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria

(2009) Michael Lazarou et al.   FEBS Journal

Making synaptic plasticity and memory last: mechanisms of translational regulation

(2009) J. D. Richter et al.   GENES & DEVELOPMENT