Integrating mitochondrial translation into the cellular context

Parallel Structural Evolution of Mitochondrial Ribosomes and OXPHOS Complexes

(2015) Eli O. van der Sluis et al.   Genome Biology and Evolution

Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia

(2015) Minal J. Menezes et al.   HUMAN MOLECULAR GENETICS

Human mitochondrial COX1 assembly into cytochrome c oxidase at a glance

(2015) S. Dennerlein et al.   JOURNAL OF CELL SCIENCE

Mutations inCOA3cause isolated complex IV deficiency associated with neuropathy, exercise intolerance, obesity, and short stature

(2015) Elsebet Ostergaard et al.   JOURNAL OF MEDICAL GENETICS

DNA interstrand cross-link repair requires replication-fork convergence

(2015) Jieqiong Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MRPS22 mutation causes fatal neonatal lactic acidosis with brain and heart abnormalities

(2015) Fabian Baertling et al.   NEUROGENETICS

The complete structure of the 55S mammalian mitochondrial ribosome

(2015) B. J. Greber et al.   SCIENCE

The structure of the human mitochondrial ribosome

(2015) A. Amunts et al.   SCIENCE

Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography

(2015) Stefan Pfeffer et al.   Nature Communications

DNA interstrand cross-link repair requires replication-fork convergence

(2015) Jieqiong Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Organization of Mitochondrial Gene Expression in Two Distinct Ribosome-Containing Assemblies

(2015) Kirsten Kehrein et al.   Cell Reports

The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly

(2015) Ya-Ting Tu et al.   Cell Reports

A Mitochondria-Specific Isoform of FASTK Is Present In Mitochondrial RNA Granules and Regulates Gene Expression and Function

(2015) Alexis A. Jourdain et al.   Cell Reports

Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis

(2015) Hana Antonicka et al.   Cell Reports

MicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation

(2014) Xiaorong Zhang et al.   CELL

Making Proteins in the Powerhouse

(2014) B. Martin Hällberg et al.   Cell Metabolism

Initial Steps in RNA Processing and Ribosome Assembly Occur at Mitochondrial DNA Nucleoids

(2014) Daniel F. Bogenhagen et al.   Cell Metabolism

Assembly factors monitor sequential hemylation of cytochromebto regulate mitochondrial translation

(2014) Markus Hildenbeutel et al.   JOURNAL OF CELL BIOLOGY

Structure of the large ribosomal subunit from human mitochondria

(2014) A. Brown et al.   SCIENCE

Functional Genomic Analysis of Human Mitochondrial RNA Processing

(2014) Ashley R. Wolf et al.   Cell Reports

Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency

(2013) Valérie Serre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules

(2013) Alexis A. Jourdain et al.   Cell Metabolism

The Mitochondrial RNA-Binding Protein GRSF1 Localizes to RNA Granules and Is Required for Posttranscriptional Mitochondrial Gene Expression

(2013) Hana Antonicka et al.   Cell Metabolism

A Mitochondrial Ribosomal and RNA Decay Pathway Blocks Cell Proliferation

(2013) Uwe Richter et al.   CURRENT BIOLOGY

Why translation counts for mitochondria - retrograde signalling links mitochondrial protein synthesis to mitochondrial biogenesis and cell proliferation

(2013) B. J. Battersby et al.   JOURNAL OF CELL SCIENCE

Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy

(2013) Christopher J Carroll et al.   JOURNAL OF MEDICAL GENETICS

Mutations in the UQCC1-Interacting Protein, UQCC2, Cause Human Complex III Deficiency Associated with Perturbed Cytochrome b Protein Expression

(2013) Elena J. Tucker et al.   PLoS Genetics

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast

(2013) Andrew Murley et al.   eLife

Mutations in C12orf62, a Factor that Couples COX I Synthesis with Cytochrome c Oxidase Assembly, Cause Fatal Neonatal Lactic Acidosis

(2012) Woranontee Weraarpachai et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Control of protein synthesis in yeast mitochondria: The concept of translational activators

(2012) Johannes M. Herrmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MITRAC Links Mitochondrial Protein Translocation to Respiratory-Chain Assembly and Translational Regulation

(2012) David U. Mick et al.   CELL

A Heme-Sensing Mechanism in the Translational Regulation of Mitochondrial Cytochrome c Oxidase Biogenesis

(2012) Iliana C. Soto et al.   Cell Metabolism

LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria

(2012) Takeshi Chujo et al.   NUCLEIC ACIDS RESEARCH

Human mitochondrial RNA decay mediated by PNPase–hSuv3 complex takes place in distinct foci

(2012) Lukasz S. Borowski et al.   NUCLEIC ACIDS RESEARCH

Role of MINOS in mitochondrial membrane architecture and biogenesis

(2012) Martin van der Laan et al.   TRENDS IN CELL BIOLOGY

Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase

(2012) Radek Szklarczyk et al.   GENOME BIOLOGY

Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

(2011) Marko Škrtić et al.   CANCER CELL

The Human Mitochondrial Transcriptome

(2011) Tim R. Mercer et al.   CELL

Exome sequencing identifies MRPL3 mutation in mitochondrial cardiomyopathy

(2011) Louise Galmiche et al.   HUMAN MUTATION

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA

(2011) C. Kukat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs

(2011) Lien K. Brzezniak et al.   RNA Biology

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

Mutation in mitochondrial ribosomal protein MRPS22 leads to Cornelia de Lange-like phenotype, brain abnormalities and hypertrophic cardiomyopathy

(2010) Paulien Smits et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Inhibition of Human Peptide Deformylase Disrupts Mitochondrial Function

(2010) S. Escobar-Alvarez et al.   MOLECULAR AND CELLULAR BIOLOGY

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That Regulates Posttranscriptional Gene Expression in Mitochondria

(2010) Florin Sasarman et al.   MOLECULAR BIOLOGY OF THE CELL

NOA1 is an essential GTPase required for mitochondrial protein synthesis

(2010) Mateusz Kolanczyk et al.   MOLECULAR BIOLOGY OF THE CELL

Small RNA sorting: matchmaking for Argonautes

(2010) Benjamin Czech et al.   NATURE REVIEWS GENETICS

Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation

(2010) David U. Mick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dual Functions of Mss51 Couple Synthesis of Cox1 to Assembly of Cytochrome c Oxidase in Saccharomyces cerevisiae Mitochondria

(2009) Xochitl Perez-Martinez et al.   MOLECULAR BIOLOGY OF THE CELL

RNase P without RNA: Identification and Functional Reconstitution of the Human Mitochondrial tRNA Processing Enzyme

(2008) Johann Holzmann et al.   CELL