Role of the NF-κB system in context-specific tuning of the inflammatory gene response

Integrative analysis suggests cell type–specific decoding of NF-κB dynamics

(2020) Erik W. Martin et al.   Science Signaling

Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics

(2020) Kim A. Ngo et al.   Cell Reports

Gene Regulatory Strategies that Decode the Duration of NFκB Dynamics Contribute to LPS- versus TNF-Specific Gene Expression

(2020) Supriya Sen et al.   Cell Systems

Fold-change detection of NF-κB at target genes with different transcript outputs

(2019) Victor C. Wong et al.   BIOPHYSICAL JOURNAL

NF-κB Signaling in Macrophages: Dynamics, Crosstalk, and Signal Integration

(2019) Michael G. Dorrington et al.   Frontiers in Immunology

Immune Differentiation Regulator p100 Tunes NF-κB Responses to TNF

(2019) Budhaditya Chatterjee et al.   Frontiers in Immunology

Genome reading by the NF-κB transcription factors

(2019) Maria Carmen Mulero et al.   NUCLEIC ACIDS RESEARCH

The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80

(2019) Emma L Smith et al.   NUCLEIC ACIDS RESEARCH

Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit

(2018) Maria Carmen Mulero et al.   BIOCHEMISTRY

Variation in Genome-Wide NF-κB RELA Binding Sites upon Microbial Stimuli and Identification of a Virus Response Profile

(2018) Lisa Borghini et al.   JOURNAL OF IMMUNOLOGY

Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation

(2018) Mingming Zhao et al.   PLOS BIOLOGY

NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression

(2018) Tabea Riedlinger et al.   FASEB JOURNAL

Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity

(2017) Vivien Ya-Fan Wang et al.   MOLECULAR CELL

Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant

(2017) Holly E. Dembinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Decision Making by Non-Integrative Processing of TLR Inputs

(2017) Ryan A. Kellogg et al.   Cell Reports

Iterative Modeling Reveals Evidence of Sequential Transcriptional Control Mechanisms

(2017) Christine S. Cheng et al.   Cell Systems

Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-κB Activation

(2017) Keara Lane et al.   Cell Systems

A Stringent Systems Approach Uncovers Gene-Specific Mechanisms Regulating Inflammation

(2016) Ann-Jay Tong et al.   CELL

Non-canonical NFκB mutations reinforce pro-survival TNF response in multiple myeloma through an autoregulatory RelB:p50 NFκB pathway

(2016) P Roy et al.   ONCOGENE

Late-phase synthesis of I B  insulates the TLR4-activated canonical NF- B pathway from noncanonical NF- B signaling in macrophages

(2016) B. Chatterjee et al.   Science Signaling

Signaling via the NFκB system

(2016) Simon Mitchell et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses

(2016) Kivia A. P. de Oliveira et al.   Genome Medicine

Late-phase synthesis of I B  insulates the TLR4-activated canonical NF- B pathway from noncanonical NF- B signaling in macrophages

(2016) B. Chatterjee et al.   Science Signaling

The Ubiquitination of NF-κB Subunits in the Control of Transcription

(2016) Patricia Collins et al.   Cells

Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection

(2015) Balaji Banoth et al.   eLife

The deubiquitinase activity of A20 is dispensable for NF- B signaling

(2014) A. De et al.   EMBO REPORTS

Fold Change of Nuclear NF-κB Determines TNF-Induced Transcription in Single Cells

(2014) Robin E.C. Lee et al.   MOLECULAR CELL

The NF-κB Genomic Landscape in Lymphoblastoid B Cells

(2014) Bo Zhao et al.   Cell Reports

Regulation of the NF-κB-Mediated Transcription of Inflammatory Genes

(2014) Dev Bhatt et al.   Frontiers in Immunology

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways

(2012) Vincent F-S Shih et al.   NATURE IMMUNOLOGY

The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements

(2012) Vivien Ya-Fan Wang et al.   Cell Reports

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding

(2011) Trevor Siggers et al.   NATURE IMMUNOLOGY

PU.1 and C/EBP  synergistically program distinct response to NF- B activation through establishing monocyte specific enhancers

(2011) F. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Encoding NF- B temporal control in response to TNF: distinct roles for the negative regulators I B  and A20

(2008) S. L. Werner et al.   GENES & DEVELOPMENT

Generation and Activation of Multiple Dimeric Transcription Factors within the NF- B Signaling System

(2008) S. Basak et al.   MOLECULAR AND CELLULAR BIOLOGY