Anatomy of a crosslinker

Proteome-Wide Structural Probing of Low-Abundant Protein Interactions by Cross-Linking Mass Spectrometry

(2020) Julius Fürsch et al.   ANALYTICAL CHEMISTRY

To Cleave or Not To Cleave in XL-MS?

(2020) B. Steigenberger et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Improving identification of in-organello protein-protein interactions using an affinity-enrichable, isotopically-coded, and mass spectrometry-cleavable chemical crosslinker

(2020) Karl A. T. Makepeace et al.   MOLECULAR & CELLULAR PROTEOMICS

Assessment of chemical‐crosslink‐assisted protein structure modeling in CASP13

(2020) J. Eduardo Fajardo et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes

(2020) Rebecca Beveridge et al.   Nature Communications

Exploring Spacer Arm Structures for Designs of Asymmetric Sulfoxide-Containing MS-Cleavable Cross-Linkers

(2020) Clinton Yu et al.   ANALYTICAL CHEMISTRY

The Conformational Preference of Chemical Cross-linkers Determines the Cross-linking Probability of Reactive Protein Residues

(2020) Zhou Gong et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Fast and Highly Efficient Affinity Enrichment of Azide-A-DSBSO Cross-Linked Peptides

(2020) Manuel Matzinger et al.   JOURNAL OF PROTEOME RESEARCH

A cross-linking mass spectrometry approach defines protein interactions in yeast mitochondria

(2020) Andreas Linden et al.   MOLECULAR & CELLULAR PROTEOMICS

A Structure-Based Mechanism for DNA Entry into the Cohesin Ring

(2020) Torahiko L. Higashi et al.   MOLECULAR CELL

The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study

(2019) Claudio Iacobucci et al.   ANALYTICAL CHEMISTRY

A Simple Cross-Linking/Mass Spectrometry Workflow for Studying System-wide Protein Interactions

(2019) Michael Götze et al.   ANALYTICAL CHEMISTRY

Prediction of an Upper Limit for the Fraction of Interprotein Cross-Links in Large-Scale In Vivo Cross-Linking Studies

(2019) Andrew Keller et al.   JOURNAL OF PROTEOME RESEARCH

An integrated workflow for crosslinking mass spectrometry

(2019) Marta L Mendes et al.   Molecular Systems Biology

PhoX: An IMAC-Enrichable Cross-Linking Reagent

(2019) Barbara Steigenberger et al.   ACS Central Science

A Click‐Chemistry‐Based Enrichable Crosslinker for Structural and Protein Interaction Analysis by Mass Spectrometry

(2019) Michael Stadlmeier et al.   CHEMBIOCHEM

Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers

(2019) Alexander X. Jones et al.   Nature Communications

Evaluation of chemical cross-linkers for in-depth structural analysis of G protein-coupled receptors through cross-linking mass spectrometry

(2019) Lisha Xia et al.   ANALYTICA CHIMICA ACTA

In Situ Structural Restraints from Cross-Linking Mass Spectrometry in Human Mitochondria

(2019) Petra S. J. Ryl et al.   JOURNAL OF PROTEOME RESEARCH

MaXLinker: Proteome-wide Cross-link Identifications with High Specificity and Sensitivity

(2019) Kumar Yugandhar et al.   MOLECULAR & CELLULAR PROTEOMICS

High-density chemical cross-linking for modeling protein interactions

(2019) Julian Mintseris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carboxylate-Selective Chemical Cross-Linkers for Mass Spectrometric Analysis of Protein Structures

(2018) Xiaoyun Zhang et al.   ANALYTICAL CHEMISTRY

Impact of Chemical Cross-Linking on Protein Structure and Function

(2018) Daniel Rozbeský et al.   ANALYTICAL CHEMISTRY

Cross-Linking/Mass Spectrometry for Studying Protein Structures and Protein-Protein Interactions: Where Are We Now and Where Should We Go from Here?

(2018) Andrea Sinz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

False discovery rate estimation and heterobifunctional cross-linkers

(2018) Lutz Fischer et al.   PLoS One

Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy

(2018) Tadeusz L. Ogorzalek et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Protein Tertiary Structure by Crosslinking/Mass Spectrometry

(2018) Michael Schneider et al.   TRENDS IN BIOCHEMICAL SCIENCES

eXL-MS: An Enhanced Cross-Linking Mass Spectrometry Workflow To Study Protein Complexes

(2018) Martial Rey et al.   ANALYTICAL CHEMISTRY

Photo-Cross-Linking Mass Spectrometry and Integrative Modeling Enables Rapid Screening of Antigen Interactions Involving Bacterial Transferrin Receptors

(2018) Daniel S. Ziemianowicz et al.   JOURNAL OF PROTEOME RESEARCH

Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology

(2018) Francis J. O’Reilly et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry

(2018) Bing Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Dynamics in Solution by Quantitative Crosslinking/Mass Spectrometry

(2018) Zhuo A. Chen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chemical cross-linking with mass spectrometry: a tool for systems structural biology

(2018) Juan D Chavez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

On the Reproducibility of Label-Free Quantitative Cross-Linking/Mass Spectrometry

(2017) Fränze Müller et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry

(2017) Devin K. Schweppe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification

(2017) Fan Liu et al.   Nature Communications

Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations

(2017) Nicholas I. Brodie et al.   Science Advances

Divide and conquer: cleavable cross-linkers to study protein conformation and protein–protein interactions

(2016) Andrea Sinz   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Quantitative Cross-linking/Mass Spectrometry Using Isotope-labeled Cross-linkers and MaxQuant

(2016) Zhuo A. Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

Blind testing of cross-linking/mass spectrometry hybrid methods in CASP11

(2016) Michael Schneider et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Blind Evaluation of Hybrid Protein Structure Analysis Methods based on Cross-Linking

(2016) Adam Belsom et al.   TRENDS IN BIOCHEMICAL SCIENCES

Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular Machines

(2016) Alexander Leitner et al.   TRENDS IN BIOCHEMICAL SCIENCES

Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states

(2016) Dan Tan et al.   eLife

A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly

(2015) Robert J. Tomko et al.   CELL

A Study into the Collision-induced Dissociation (CID) Behavior of Cross-Linked Peptides

(2015) Sven H. Giese et al.   MOLECULAR & CELLULAR PROTEOMICS

Serum Albumin Domain Structures in Human Blood Serum by Mass Spectrometry and Computational Biology

(2015) Adam Belsom et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry

(2015) Fan Liu et al.   NATURE METHODS

A Newin VivoCross-linking Mass Spectrometry Platform to Define Protein–Protein Interactions in Living Cells

(2014) Robyn M. Kaake et al.   MOLECULAR & CELLULAR PROTEOMICS

Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes

(2014) Alexander Leitner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

(2013) Zhengqiu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quantitative cross-linking/mass spectrometry using isotope-labelled cross-linkers

(2013) Lutz Fischer et al.   Journal of Proteomics

Selective enrichment and identification of cross-linked peptides to study 3-D structures of protein complexes by mass spectrometry

(2012) Hansuk Buncherd et al.   Journal of Proteomics

False discovery rate estimation for cross-linked peptides identified by mass spectrometry

(2012) Thomas Walzthoeni et al.   NATURE METHODS

Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry

(2010) Zhuo Angel Chen et al.   EMBO JOURNAL

An Isotopically Coded CID-cleavable Biotinylated Cross-linker for Structural Proteomics

(2010) Evgeniy V. Petrotchenko et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification of Cross-Linked Peptides after Click-Based Enrichment Using Sequential Collision-Induced Dissociation and Electron Transfer Dissociation Tandem Mass Spectrometry

(2009) Saiful M. Chowdhury et al.   ANALYTICAL CHEMISTRY

Intra-Molecular Cross-Linking of Acidic Residues for Protein Structure Studies

(2009) Petr Novák et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometry

(2009) Sebyung Kang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Chances and pitfalls of chemical cross-linking with amine-reactive N-hydroxysuccinimide esters

(2008) Stefan Kalkhof et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Identification of Protein-Protein Interactions and Topologies in Living Cells with Chemical Cross-linking and Mass Spectrometry

(2008) Haizhen Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS