In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
出版年份 2021 全文链接
标题
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
作者
关键词
SARS-CoV-2, RNA secondary structure, host factor, RBP binding prediction, drug reproposing
出版物
CELL
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2021-02-10
DOI
10.1016/j.cell.2021.02.008
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Predicting dynamic cellular protein–RNA interactions by deep learning using in vivo RNA structures
- (2021) Lei Sun et al. CELL RESEARCH
- An interactive web-based dashboard to track COVID-19 in real time
- (2020) Ensheng Dong et al. LANCET INFECTIOUS DISEASES
- A new coronavirus associated with human respiratory disease in China
- (2020) Fan Wu et al. NATURE
- Another Decade, Another Coronavirus
- (2020) Stanley Perlman NEW ENGLAND JOURNAL OF MEDICINE
- Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
- (2020) Renhong Yan et al. SCIENCE
- The Architecture of SARS-CoV-2 Transcriptome
- (2020) Dongwan Kim et al. CELL
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals
- (2020) Ling Ni et al. IMMUNITY
- RIC-seq for global in situ profiling of RNA–RNA spatial interactions
- (2020) Zhaokui Cai et al. NATURE
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Macromolecular modeling and design in Rosetta: recent methods and frameworks
- (2020) Julia Koehler Leman et al. NATURE METHODS
- RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses: a first look
- (2020) Ramya Rangan et al. RNA
- Structure of the RNA-dependent RNA polymerase from COVID-19 virus
- (2020) Yan Gao et al. SCIENCE
- Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus
- (2020) Bette Korber et al. CELL
- Advances in oligonucleotide drug delivery
- (2020) Thomas C. Roberts et al. NATURE REVIEWS DRUG DISCOVERY
- The coding capacity of SARS-CoV-2
- (2020) Yaara Finkel et al. NATURE
- SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
- (2020) Steffen Klein et al. Nature Communications
- RNA structure maps across mammalian cellular compartments
- (2019) Lei Sun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RAxML-NG: a fast, scalable and user-friendly tool for maximum likelihood phylogenetic inference
- (2019) Alexey M Kozlov et al. BIOINFORMATICS
- In vivo analysis of influenza A mRNA secondary structures identifies critical regulatory motifs
- (2019) Lisa Marie Simon et al. NUCLEIC ACIDS RESEARCH
- An RNA-centric dissection of host complexes controlling flavivirus infection
- (2019) Yaw Shin Ooi et al. Nature Microbiology
- icSHAPE-pipe: A comprehensive toolkit for icSHAPE data analysis and evaluation
- (2019) Pan Li et al. METHODS
- Parallelization of MAFFT for large-scale multiple sequence alignments
- (2018) Tsukasa Nakamura et al. BIOINFORMATICS
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- RNA–protein interaction detection in living cells
- (2018) Muthukumar Ramanathan et al. NATURE METHODS
- Principles for targeting RNA with drug-like small molecules
- (2018) Katherine Deigan Warner et al. NATURE REVIEWS DRUG DISCOVERY
- SWISS-MODEL: homology modelling of protein structures and complexes
- (2018) Andrew Waterhouse et al. NUCLEIC ACIDS RESEARCH
- New Era of Studying RNA Secondary Structure and Its Influence on Gene Regulation in Plants
- (2018) Xiaofei Yang et al. Frontiers in Plant Science
- Inhibition of Stress Granule Formation by Middle East Respiratory Syndrome Coronavirus 4a Accessory Protein Facilitates Viral Translation, Leading to Efficient Virus Replication
- (2018) Keisuke Nakagawa et al. JOURNAL OF VIROLOGY
- COMRADES determines in vivo RNA structures and interactions
- (2018) Omer Ziv et al. NATURE METHODS
- Integrative Analysis of Zika Virus Genome RNA Structure Reveals Critical Determinants of Viral Infectivity
- (2018) Pan Li et al. Cell Host & Microbe
- Pervasive tertiary structure in the dengue virus RNA genome
- (2018) Elizabeth A. Dethoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rfam 13.0: shifting to a genome-centric resource for non-coding RNA families
- (2017) Ioanna Kalvari et al. NUCLEIC ACIDS RESEARCH
- Dengue virus genomic variation associated with mosquito adaptation defines the pattern of viral non-coding RNAs and fitness in human cells
- (2017) Claudia V. Filomatori et al. PLoS Pathogens
- Operon mRNAs are organized into ORF-centric structures that predict translation efficiency
- (2017) David H Burkhardt et al. eLife
- RNA Regulations and Functions Decoded by Transcriptome-wide RNA Structure Probing
- (2017) Meiling Piao et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure
- (2016) Zhipeng Lu et al. CELL
- Innate immune evasion strategies of DNA and RNA viruses
- (2016) Dia C Beachboard et al. CURRENT OPINION IN MICROBIOLOGY
- The Coding Region of the HCV Genome Contains a Network of Regulatory RNA Structures
- (2016) Nathan Pirakitikulr et al. MOLECULAR CELL
- In Vivo Mapping of Eukaryotic RNA Interactomes Reveals Principles of Higher-Order Organization and Regulation
- (2016) Jong Ghut Ashley Aw et al. MOLECULAR CELL
- Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence
- (2016) Feifei Chen et al. Nature Chemical Biology
- DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo
- (2016) Meghan Zubradt et al. NATURE METHODS
- Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
- (2016) Eric L Van Nostrand et al. NATURE METHODS
- POSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins
- (2016) Boqin Hu et al. NUCLEIC ACIDS RESEARCH
- Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease
- (2016) B. M. Akiyama et al. SCIENCE
- Overlapping Local and Long-Range RNA-RNA Interactions Modulate Dengue Virus Genome Cyclization and Replication
- (2015) Luana de Borba et al. JOURNAL OF VIROLOGY
- Structural imprints in vivo decode RNA regulatory mechanisms
- (2015) Robert C. Spitale et al. NATURE
- N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
- (2015) Nian Liu et al. NATURE
- PLIP: fully automated protein–ligand interaction profiler
- (2015) Sebastian Salentin et al. NUCLEIC ACIDS RESEARCH
- SHAPE analysis of the RNA secondary structure of the Mouse Hepatitis Virus 5’ untranslated region and N-terminal nsp1 coding sequences
- (2015) Dong Yang et al. VIROLOGY
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- RiboVision suite for visualization and analysis of ribosomes
- (2014) Chad R. Bernier et al. FARADAY DISCUSSIONS
- Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation
- (2014) Karl A. P. Payne et al. NATURE
- c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry–related pockets
- (2014) Aiming Ren et al. Nature Chemical Biology
- Functional long-range RNA–RNA interactions in positive-strand RNA viruses
- (2014) Beth L. Nicholson et al. NATURE REVIEWS MICROBIOLOGY
- Infernal 1.1: 100-fold faster RNA homology searches
- (2013) E. P. Nawrocki et al. BIOINFORMATICS
- A Target-Disease Network Model of Second-Generation BCR-ABL Inhibitor Action in Ph+ ALL
- (2013) Uwe Rix et al. PLoS One
- Computational identification of functional RNA homologs in metagenomic data
- (2013) Eric P. Nawrocki et al. RNA Biology
- Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
- (2013) D. M. Molina et al. SCIENCE
- Recognition modes of RNA tetraloops and tetraloop-like motifs by RNA-binding proteins
- (2013) Roopa Thapar et al. Wiley Interdisciplinary Reviews-RNA
- CD-HIT: accelerated for clustering the next-generation sequencing data
- (2012) Limin Fu et al. BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
- Uridine Composition of the Poly-U/UC Tract of HCV RNA Defines Non-Self Recognition by RIG-I
- (2012) Gretja Schnell et al. PLoS Pathogens
- ViennaRNA Package 2.0
- (2011) Ronny Lorenz et al. Algorithms for Molecular Biology
- Hepatitis C Virus Hijacks P-Body and Stress Granule Components around Lipid Droplets
- (2011) Y. Ariumi et al. JOURNAL OF VIROLOGY
- The Polypyrimidine Tract-Binding Protein Affects Coronavirus RNA Accumulation Levels and Relocalizes Viral RNAs to Novel Cytoplasmic Domains Different from Replication-Transcription Sites
- (2011) I. Sola et al. JOURNAL OF VIROLOGY
- Global landscape of HIV–human protein complexes
- (2011) Stefanie Jäger et al. NATURE
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- Diverse roles of host RNA binding proteins in RNA virus replication
- (2011) Zhenghe Li et al. RNA Biology
- RNAstructure: software for RNA secondary structure prediction and analysis
- (2010) Jessica S Reuter et al. BMC BIOINFORMATICS
- starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
- (2010) Jian-Hua Yang et al. NUCLEIC ACIDS RESEARCH
- VARNA: Interactive drawing and editing of the RNA secondary structure
- (2009) Kévin Darty et al. BIOINFORMATICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Architecture and secondary structure of an entire HIV-1 RNA genome
- (2009) Joseph M. Watts et al. NATURE
- IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR
- (2009) S. Weinlich et al. RNA
- How RNA Unfolds and Refolds
- (2008) Pan T.X. Li et al. Annual Review of Biochemistry
- Oligonucleotide antiviral therapeutics: Antisense and RNA interference for highly pathogenic RNA viruses
- (2008) Kevin B. Spurgers et al. ANTIVIRAL RESEARCH
- RNA STRAND: The RNA Secondary Structure and Statistical Analysis Database
- (2008) Mirela Andronescu et al. BMC BIOINFORMATICS
- Structural Lability in Stem–Loop 1 Drives a 5′ UTR–3′ UTR Interaction in Coronavirus Replication
- (2008) Lichun Li et al. JOURNAL OF MOLECULAR BIOLOGY
- Accurate SHAPE-directed RNA structure determination
- (2008) K. E. Deigan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Viral IRES RNA structures and ribosome interactions
- (2008) Jeffrey S. Kieft TRENDS IN BIOCHEMICAL SCIENCES
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