Effect of casein kinase 1α inhibition on autophagy flux and the AKT/phospho-β-catenin (S552) axis in HCT116, a RAS-mutated colorectal cancer cell line
出版年份 2021 全文链接
标题
Effect of casein kinase 1α inhibition on autophagy flux and the AKT/phospho-β-catenin (S552) axis in HCT116, a RAS-mutated colorectal cancer cell line
作者
关键词
-
出版物
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Volume 99, Issue 3, Pages 284-293
出版商
Canadian Science Publishing
发表日期
2021-02-26
DOI
10.1139/cjpp-2020-0449
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Delayed effects of sulfur mustard on autophagy suppression in chemically-injured lung tissue
- (2020) Marzieh Eghtedardoost et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The regulatory activity of autophagy in conjunctival fibroblasts and its possible role in vernal keratoconjunctivitis
- (2020) Paola Brun et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation
- (2020) Simone C. da Silva Rosa et al. Autophagy
- Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells
- (2020) Sanaz Dastghaib et al. Cells
- Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy
- (2019) Jiangbo Wang et al. BIOCHEMICAL JOURNAL
- Autophagic flux modulation by Wnt/β-catenin pathway inhibition in hepatocellular carcinoma
- (2019) Lilia Turcios et al. PLoS One
- Autophagy and cancer research in Iran
- (2019) Pooneh Mokarram et al. Autophagy
- RAS mutations in human cancers: Roles in precision medicine
- (2019) Avaniyapuram Kannan Murugan et al. SEMINARS IN CANCER BIOLOGY
- Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates
- (2019) Kimia Sheikholeslami et al. Cancers
- Positive Correlation Between Somatic Mutations in RAS Gene and Colorectal Cancer in Telangana Population: Hospital-Based Study in a Cosmopolitan City
- (2019) Kalal Iravathy Goud et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Simvastatin Increases Temozolomide‐induced Cell Death by Targeting the Fusion of Autophagosomes and Lysosomes
- (2019) Shahla Shojaei et al. FEBS Journal
- Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition
- (2019) Arya Emami et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Signaling pathways involved in colorectal cancer progression
- (2019) Zahra Koveitypour et al. Cell and Bioscience
- CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy
- (2018) Junchao Cai et al. NATURE CELL BIOLOGY
- Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer
- (2017) Lu Zhang et al. JNCI-Journal of the National Cancer Institute
- The regulation of β-catenin activity and function in cancer: therapeutic opportunities
- (2017) Shuang Shang et al. Oncotarget
- Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways
- (2017) Sabrina Manni et al. Oncotarget
- Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells
- (2017) Javad Alizadeh et al. Scientific Reports
- Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer
- (2017) Lu Zhang et al. JNCI-Journal of the National Cancer Institute
- Identification of modulators of autophagic flux in an image-based high content siRNA screen
- (2016) Christopher M. Hale et al. Autophagy
- Wnt signaling in cancer
- (2016) T Zhan et al. ONCOGENE
- Role of Wnt/β-catenin pathway in inducing autophagy and apoptosis in multiple myeloma cells
- (2016) Nan Su et al. Oncology Letters
- β-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation
- (2016) Ana Sastre-Perona et al. Oncotarget
- The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
- (2015) Valerie R Wiersma et al. Autophagy
- Portrait of the PI3K/AKT pathway in colorectal cancer
- (2015) Stine Aske Danielsen et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Regulation of Autophagy of Prostate Cancer Cells by β-Catenin Signaling
- (2015) Rongkai Lin et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Casein kinase 1α–dependent feedback loop controls autophagy in RAS-driven cancers
- (2015) Jit Kong Cheong et al. JOURNAL OF CLINICAL INVESTIGATION
- WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling
- (2015) Steffen Ormanns et al. Oncotarget
- Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins
- (2014) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Integrated Genomic Characterization of Papillary Thyroid Carcinoma
- (2014) Nishant Agrawal et al. CELL
- The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
- (2014) David Heras-Sandoval et al. CELLULAR SIGNALLING
- Casein kinase 1 and Wnt/β-catenin signaling
- (2014) Cristina-Maria Cruciat CURRENT OPINION IN CELL BIOLOGY
- The potential of targeting Wnt/β-catenin in colon cancer
- (2014) Ana Sebio et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia
- (2014) Marcus Järås et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Multivesicular GSK3 Sequestration upon Wnt Signaling Is Controlled by p120-Catenin/Cadherin Interaction with LRP5/6
- (2014) Meritxell Vinyoles et al. MOLECULAR CELL
- mTOR and autophagy: A dynamic relationship governed by nutrients and energy
- (2014) E.A. Dunlop et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
- (2014) G. Karsli-Uzunbas et al. Cancer Discovery
- Potential Targets for Prevention of Colorectal Cancer: a Focus on PI3K/Akt/mTOR and Wnt Pathways
- (2013) Ashok Kumar Pandurangan Asian Pacific Journal of Cancer Prevention
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- Life in the balance – a mechanistic view of the crosstalk between autophagy and apoptosis
- (2013) Assaf D. Rubinstein et al. JOURNAL OF CELL SCIENCE
- mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
- (2013) Francesca Nazio et al. NATURE CELL BIOLOGY
- The -Catenin Destruction Complex
- (2012) J. L. Stamos et al. Cold Spring Harbor Perspectives in Biology
- Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle
- (2011) Saeid Ghavami et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions
- (2011) Piotr Szyniarowski et al. Autophagy
- Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
- (2011) J. Y. Guo et al. GENES & DEVELOPMENT
- Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation
- (2011) Min-Jung Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR
- (2011) Shanshan Duan et al. MOLECULAR CELL
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53
- (2011) Saeid Ghavami et al. PLoS One
- Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells
- (2010) Shengbing Huang et al. Autophagy
- Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c
- (2010) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Regulation of autophagy in mammals and its interplay with apoptosis
- (2010) Gian Maria Fimia et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Phosphoinositide 3-Kinase Signaling Mediates β-Catenin Activation in Intestinal Epithelial Stem and Progenitor Cells in Colitis
- (2010) Goo Lee et al. GASTROENTEROLOGY
- Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
- (2010) Rebecca Lock et al. MOLECULAR BIOLOGY OF THE CELL
- The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres
- (2010) Shailender S Kanwar et al. Molecular Cancer
- Role of BNIP3 in TNF-induced cell death — TNF upregulates BNIP3 expression
- (2009) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss
- (2009) Reid A. Phelps et al. CELL
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells
- (2008) Jie Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brevinin-2R1 semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway
- (2008) Saeid Ghavami et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway
- (2008) M Lodyga et al. ONCOGENE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started