PSB 603 – a known selective adenosine A2B receptor antagonist – has anti-inflammatory activity in mice

Regulation of C-reactive protein conformation in inflammation

(2019) ZhenYu Yao et al.   INFLAMMATION RESEARCH

Characterisation of endogenous A 2A and A 2B receptor-mediated cyclic AMP responses in HEK 293 cells using the GloSensor™ biosensor: Evidence for an allosteric mechanism of action for the A 2B -selective antagonist PSB 603

(2018) Joelle Goulding et al.   BIOCHEMICAL PHARMACOLOGY

Effects of Non-Steroidal Anti-Inflammatory Drugs on Serum Proinflammatory Cytokines in the Treatment of Ankylosing Spondylitis

(2018) Yong Yan et al.   Biochemistry and Cell Biology

Adenosine signaling and the immune system: When a lot could be too much

(2018) Luca Antonioli et al.   IMMUNOLOGY LETTERS

Plasma C-reactive protein levels in bipolar depression during cyclooxygenase-2 inhibitor combination treatment

(2018) David Edberg et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure

(2018) Michael Härter et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of novel xanthine derivatives as potent and selective A 2B adenosine receptor antagonists for the treatment of chronic inflammatory airway diseases

(2017) Sujay Basu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase

(2017) Antonella Peduto et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Preclinical evaluation of the urokinase receptor-derived peptide UPARANT as an anti-inflammatory drug

(2017) Serena Boccella et al.   INFLAMMATION RESEARCH

Antioxidants: Friend or foe?

(2017) R. Sarangarajan et al.   Asian Pacific Journal of Tropical Medicine

The A 2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS production in colorectal cancer cells via adenosine receptor-independent mechanism

(2016) Christina Mølck et al.   CANCER LETTERS

Reparative inflammation takes charge of tissue regeneration

(2016) Michael Karin et al.   NATURE

Antinociceptive, anti-inflammatory and smooth muscle relaxant activities of the pyrrolo[3,4-d]pyridazinone derivatives: Possible mechanisms of action

(2015) Szczepan Mogilski et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors

(2015) Mohamad Wessam Alnouri et al.   Purinergic Signalling

Adenosine and inflammation: what's new on the horizon?

(2014) Luca Antonioli et al.   DRUG DISCOVERY TODAY

Oxidative Stress, Prooxidants, and Antioxidants: The Interplay

(2014) Anu Rahal et al.   Biomed Research International

Adenosine signaling during acute and chronic disease states

(2013) Harry Karmouty-Quintana et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Antiproliferative effects of selective adenosine receptor agonists and antagonists on human lymphocytes: evidence for receptor-independent mechanisms

(2013) Anke C. Schiedel et al.   Purinergic Signalling

Synthesis, acute toxicity and anti-inflammatory effect of bornyl salicylate, a salicylic acid derivative

(2012) Renata Marcia Costa Vasconcelos et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema

(2012) Zheng Xu et al.   Journal of Inflammation-London

The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: Role in ligand binding and receptor function

(2011) Anke C. Schiedel et al.   BIOCHEMICAL PHARMACOLOGY

Anti-Inflammatory Effects of Seeds of the Tropical Fruit Camu-Camu (Myrciaria dubia)

(2011) Kazunaga YAZAWA et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

1-Alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: Development and Characterization of Adenosine A2BReceptor Antagonists and a New Radioligand with Subnanomolar Affinity and Subtype Specificity

(2009) Thomas Borrmann et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anti-Inflammatory Pharmacotherapy with Ketoprofen Ameliorates Experimental Lymphatic Vascular Insufficiency in Mice

(2009) Kenta Nakamura et al.   PLoS One

A2B adenosine receptors in immunity and inflammation

(2009) György Haskó et al.   TRENDS IN IMMUNOLOGY

Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase-9 (MMP-9) in leukocyte infiltration in a model of experimental peritonitis

(2008) Elzbieta Kolaczkowska et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia

(2008) Andras Bilkei-Gorzo et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY