标题
Small Nucleic Acids and the Path to the Clinic for Anti-CRISPR
作者
关键词
-
出版物
BIOCHEMICAL PHARMACOLOGY
Volume -, Issue -, Pages 114492
出版商
Elsevier BV
发表日期
2021-02-27
DOI
10.1016/j.bcp.2021.114492
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- N-of-1 drugs push biopharma frontiers
- (2020) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- CRISPR-engineered T cells in patients with refractory cancer
- (2020) Edward A. Stadtmauer et al. SCIENCE
- The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy
- (2020) Annemieke Aartsma-Rus et al. Nucleic Acid Therapeutics
- A Small Molecule-Controlled Cas9 Repressible System
- (2020) Youjun Wu et al. Molecular Therapy-Nucleic Acids
- Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity
- (2020) Sabine Aschenbrenner et al. Science Advances
- Potent CRISPR-Cas9 inhibitors fromStaphylococcusgenomes
- (2020) Kyle E. Watters et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
- (2020) Tuo Wei et al. Nature Communications
- Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives
- (2020) Víctor López Del Amo et al. Cell Reports
- Latest Developed Strategies to Minimize the Off-Target Effects in CRISPR-Cas-Mediated Genome Editing
- (2020) Muhammad Naeem et al. Cells
- A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy
- (2020) Daisuke Matsumoto et al. Communications Biology
- CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review
- (2019) Haris Babačić et al. PLoS One
- Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalNAc-siRNA conjugates
- (2019) Maja M Janas et al. NUCLEIC ACIDS RESEARCH
- Adeno-associated virus vector as a platform for gene therapy delivery
- (2019) Dan Wang et al. NATURE REVIEWS DRUG DISCOVERY
- A microRNA-inducible CRISPR–Cas9 platform serves as a microRNA sensor and cell-type-specific genome regulation tool
- (2019) Xi-Wen Wang et al. NATURE CELL BIOLOGY
- CRISPR/Cas9 technology as a potent molecular tool for gene therapy
- (2019) Ansar Karimian et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Gymnotic Delivery of LNA Mixmers Targeting Viral SREs Induces HIV-1 mRNA Degradation
- (2019) Frank Hillebrand et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9
- (2019) Basudeb Maji et al. CELL
- Rare Opportunities: CRISPR/Cas-Based Therapy Development for Rare Genetic Diseases
- (2019) Panayiota Papasavva et al. Molecular Diagnosis & Therapy
- Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
- (2019) Gavin J. Knott et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- An anti-CRISPR protein disables type V Cas12a by acetylation
- (2019) Liyong Dong et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila
- (2019) Hagar Meltzer et al. Nature Communications
- Rationally Designed Small Nucleic Acid-Based Inhibitors of CRISPR-Cas9
- (2019) Christopher L. Barkau et al. Nucleic Acid Therapeutics
- Steric Inhibition of 5′ UTR Regulatory Elements Results in Upregulation of Human CFTR
- (2019) Shruti Sasaki et al. MOLECULAR THERAPY
- Anti‐CRISPR AcrIIC3 discriminates between Cas9 orthologs via targeting the variable surface of the HNH nuclease domain
- (2019) Youngim Kim et al. FEBS Journal
- CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia
- (2019) Lei Xu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tissue-restricted Genome Editing in vivo Specified by MicroRNA-repressible Anti-CRISPR Proteins
- (2019) Jooyoung Lee et al. RNA
- Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy
- (2019) Mayumi Takahashi et al. Molecular Therapy-Nucleic Acids
- Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease
- (2019) Jinkuk Kim et al. NEW ENGLAND JOURNAL OF MEDICINE
- AcrIIA5 Inhibits a Broad Range of Cas9 Orthologs by Preventing DNA Target Cleavage
- (2019) Guoxu Song et al. Cell Reports
- Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing
- (2019) Bianca Garcia et al. Cell Reports
- Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017–2019
- (2019) Jacqueline Rüger et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Versatile High-Throughput Fluorescence Assay for Monitoring Cas9 Activity
- (2018) Kyle J. Seamon et al. ANALYTICAL CHEMISTRY
- CRISPR base editors: genome editing without double-stranded breaks
- (2018) Ayman Eid et al. BIOCHEMICAL JOURNAL
- Chimeric Guides Probe and Enhance Cas9 Biochemical Activity
- (2018) Zachary J. Kartje et al. BIOCHEMISTRY
- Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation
- (2018) Ahmed Mahas et al. BIOTECHNOLOGY ADVANCES
- Delivering CRISPR: a review of the challenges and approaches
- (2018) Christopher A. Lino et al. DRUG DELIVERY
- Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development
- (2018) Shalini Andersson et al. DRUG DISCOVERY TODAY
- Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells
- (2018) Amy E. Arnold et al. Molecular Therapy-Nucleic Acids
- Strategies for controlling CRISPR/Cas9 off-target effects and biological variations in mammalian genome editing experiments
- (2018) Michelle L. Kimberland et al. JOURNAL OF BIOTECHNOLOGY
- OUP accepted manuscript
- (2018) NUCLEIC ACIDS RESEARCH
- Discovery of widespread Type I and Type V CRISPR-Cas inhibitors
- (2018) Nicole D. Marino et al. SCIENCE
- Systematic discovery of natural CRISPR-Cas12a inhibitors
- (2018) Kyle E. Watters et al. SCIENCE
- CRISPR-Based Technologies: Impact of RNA-Targeting Systems
- (2018) Michael P. Terns MOLECULAR CELL
- Synthetic switch to minimize CRISPR off-target effects by self-restricting Cas9 transcription and translation
- (2018) Chih-Che Shen et al. NUCLEIC ACIDS RESEARCH
- Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways
- (2018) Maire F Osborn et al. NUCLEIC ACIDS RESEARCH
- Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo
- (2018) Annabelle Biscans et al. NUCLEIC ACIDS RESEARCH
- Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity
- (2018) Daniel O’Reilly et al. NUCLEIC ACIDS RESEARCH
- Structural basis of CRISPR–SpyCas9 inhibition by an anti-CRISPR protein
- (2017) De Dong et al. NATURE
- The chemical evolution of oligonucleotide therapies of clinical utility
- (2017) Anastasia Khvorova et al. NATURE BIOTECHNOLOGY
- Towards CRISPR/Cas crops - bringing together genomics and genome editing
- (2017) Armin Scheben et al. NEW PHYTOLOGIST
- Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes
- (2017) Michael Tanowitz et al. NUCLEIC ACIDS RESEARCH
- An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9
- (2017) Alexander P. Hynes et al. Nature Microbiology
- Disabling Cas9 by an anti-CRISPR DNA mimic
- (2017) Jiyung Shin et al. Science Advances
- Naturally Occurring Off-Switches for CRISPR-Cas9
- (2016) April Pawluk et al. CELL
- Development of antibody-siRNA conjugate targeted to cardiac and skeletal muscles
- (2016) Tsukasa Sugo et al. JOURNAL OF CONTROLLED RELEASE
- A Self-restricted CRISPR System to Reduce Off-target Effects
- (2016) Yanhao Chen et al. MOLECULAR THERAPY
- CRISPR gene-editing tested in a person for the first time
- (2016) David Cyranoski NATURE
- Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3
- (2016) Xiaofei Wang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
- (2016) Omar O. Abudayyeh et al. SCIENCE
- Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3
- (2016) Xiaofei Wang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins
- (2015) Joseph Bondy-Denomy et al. NATURE
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- A split-Cas9 architecture for inducible genome editing and transcription modulation
- (2015) Bernd Zetsche et al. NATURE BIOTECHNOLOGY
- A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae
- (2015) Andrew Hammond et al. NATURE BIOTECHNOLOGY
- Small molecule–triggered Cas9 protein with improved genome-editing specificity
- (2015) Kevin M Davis et al. Nature Chemical Biology
- Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages
- (2015) Xue-hai Liang et al. NUCLEIC ACIDS RESEARCH
- Opinion: Is CRISPR-based gene drive a biocontrol silver bullet or global conservation threat?: Fig. 1.
- (2015) Bruce L. Webber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquitoAnopheles stephensi
- (2015) Valentino M. Gantz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
- (2014) S. Ramakrishna et al. GENOME RESEARCH
- Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
- (2014) S. Kim et al. GENOME RESEARCH
- Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing
- (2014) Jayaprakash K. Nair et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Microhomology-based choice of Cas9 nuclease target sites
- (2014) Sangsu Bae et al. NATURE METHODS
- Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates
- (2014) Trinna L. Cuellar et al. NUCLEIC ACIDS RESEARCH
- Antisense Oligonucleotides Capable of Promoting Specific Target mRNA Reduction via Competing RNase H1-Dependent and Independent Mechanisms
- (2014) Timothy A. Vickers et al. PLoS One
- A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa
- (2014) A. Pawluk et al. mBio
- Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
- (2014) Shota Nakade et al. Nature Communications
- Phosphorothioates, Essential Components of Therapeutic Oligonucleotides
- (2014) Fritz Eckstein Nucleic Acid Therapeutics
- Targeting Protein-Protein Interaction by Small Molecules
- (2013) Lingyan Jin et al. Annual Review of Pharmacology and Toxicology
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- Influence of diverse chemical modifications on the ADME characteristics and toxicology of antisense oligonucleotides
- (2013) Mehrdad Dirin et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System
- (2013) Kabin Xie et al. Molecular Plant
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- A Chemical View of Oligonucleotides for Exon Skipping and Related Drug Applications
- (2013) Peter Järver et al. Nucleic Acid Therapeutics
- Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system
- (2012) Joe Bondy-Denomy et al. NATURE
- The solution structure of double helical arabino nucleic acids (ANA and 2′F-ANA): effect of arabinoses in duplex-hairpin interconversion
- (2012) Nerea Martín-Pintado et al. NUCLEIC ACIDS RESEARCH
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis
- (2012) Y.-d. Yao et al. Science Translational Medicine
- Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids
- (2012) Naira Souleimanian et al. Molecular Therapy-Nucleic Acids
- Rational design of cationic lipids for siRNA delivery
- (2010) Sean C Semple et al. NATURE BIOTECHNOLOGY
- Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents
- (2009) C. A. Stein et al. NUCLEIC ACIDS RESEARCH
- T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice
- (2008) Priti Kumar et al. CELL
- Clinical gene therapy using recombinant adeno-associated virus vectors
- (2008) C Mueller et al. GENE THERAPY
- Delivery Vehicles for Small Interfering RNA In Vivo
- (2008) Antonin R. de Fougerolles HUMAN GENE THERAPY
- Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis
- (2008) Md Rowshon Alam et al. NUCLEIC ACIDS RESEARCH
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