Anti‐CRISPR AcrIIC3 discriminates between Cas9 orthologs via targeting the variable surface of the HNH nuclease domain

Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins

(2019) Yalan Zhu et al.   MOLECULAR CELL

Structural insights into the inactivation of CRISPR-Cas systems by diverse anti-CRISPR proteins

(2018) Yuwei Zhu et al.   BMC BIOLOGY

Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiae

(2018) Erianna M. Basgall et al.   MICROBIOLOGY-SGM

Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

(2018) Alexander P. Hynes et al.   Nature Communications

Solution structure and dynamics of anti-CRISPR AcrIIA4, the Cas9 inhibitor

(2018) Iktae Kim et al.   Scientific Reports

Phage-Encoded Anti-CRISPR Defenses

(2018) Sabrina Y. Stanley et al.   Annual Review of Genetics

Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race

(2018) Liang Liu et al.   MOLECULAR CELL

Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

(2018) Fuguo Jiang et al.   MOLECULAR CELL

Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9

(2018) Felix Bubeck et al.   NATURE METHODS

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems

(2017) Mari Yamada et al.   MOLECULAR CELL

Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9

(2017) Hui Yang et al.   MOLECULAR CELL

Structural basis of CRISPR–SpyCas9 inhibition by an anti-CRISPR protein

(2017) De Dong et al.   NATURE

Crystal structure of an anti-CRISPR protein, AcrIIA1

(2017) Donghyun Ka et al.   NUCLEIC ACIDS RESEARCH

Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein

(2017) April Pawluk et al.   mBio

The Discovery, Mechanisms, and Evolutionary Impact of Anti-CRISPRs

(2017) Adair L. Borges et al.   Annual Review of Virology

Disabling Cas9 by an anti-CRISPR DNA mimic

(2017) Jiyung Shin et al.   Science Advances

Naturally Occurring Off-Switches for CRISPR-Cas9

(2016) April Pawluk et al.   CELL

Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3

(2016) Xiaofei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

(2016) F. Jiang et al.   SCIENCE

Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3

(2016) Xiaofei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species

(2016) April Pawluk et al.   Nature Microbiology

Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins

(2015) Joseph Bondy-Denomy et al.   NATURE

A Cas9-guide RNA complex preorganized for target DNA recognition

(2015) F. Jiang et al.   SCIENCE

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

(2014) Carolin Anders et al.   NATURE

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

(2014) M. Jinek et al.   SCIENCE

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system

(2012) Joe Bondy-Denomy et al.   NATURE

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY