The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy

Autophagy and disease: unanswered questions

(2020) Ying Yang et al.   CELL DEATH AND DIFFERENTIATION

Viral Ubiquitin and Ubiquitin-Like Deconjugases—Swiss Army Knives for Infection

(2020) Maria Grazia Masucci   Biomolecules

The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity

(2019) Hong Peng et al.   Autophagy

The Global Landscape of EBV-Associated Tumors

(2019) Claire Shannon-Lowe et al.   Frontiers in Oncology

A Diversity of Selective Autophagy Receptors Determines the Specificity of the Autophagy Pathway

(2019) Vladimir Kirkin et al.   MOLECULAR CELL

14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases

(2019) Soham Gupta et al.   PLoS Pathogens

Autophagy during viral infection — a double-edged sword

(2018) Younho Choi et al.   NATURE REVIEWS MICROBIOLOGY

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome

(2018) Soham Gupta et al.   PLoS Pathogens

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Regulation of selective autophagy: the p62/SQSTM1 paradigm

(2017) Trond Lamark et al.   Essays in Biochemistry

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy

(2017) Qiong Lin et al.   JOURNAL OF CELL SCIENCE

The Arf GEF GBF1 and Arf4 synergize with the sensory receptor cargo, rhodopsin, to regulate ciliary membrane trafficking

(2017) Jing Wang et al.   JOURNAL OF CELL SCIENCE

Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination

(2017) YouJin Lee et al.   Cell Reports

Mechanisms of Selective Autophagy

(2016) Gabriele Zaffagnini et al.   JOURNAL OF MOLECULAR BIOLOGY

Involvement of the N-Terminal Deubiquitinating Protease Domain of Human Cytomegalovirus UL48 Tegument Protein in Autoubiquitination, Virion Stability, and Virus Entry

(2016) Young-Eui Kim et al.   JOURNAL OF VIROLOGY

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

(2016) Ji-An Pan et al.   MOLECULAR CELL

Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson’s disease

(2016) Pingping Song et al.   Protein & Cell

Penta-EF-Hand Protein Peflin Is a Negative Regulator of ER-To-Golgi Transport

(2016) Mariah Rayl et al.   PLoS One

The pros and cons of autophagic flux among herpesviruses

(2015) Charles Grose et al.   Autophagy

Inhibition of autophagy in EBV-positive Burkitt’s lymphoma cells enhances EBV lytic genes expression and replication

(2015) A De Leo et al.   Cell Death & Disease

Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy

(2015) Bettina Wurzer et al.   eLife

Molecular basis of the regulation of Beclin 1-dependent autophagy by the γ-herpesvirus 68 Bcl-2 homolog M11

(2014) Sangita C. Sinha et al.   Autophagy

Epstein-Barr Virus Blocks the Autophagic Flux and Appropriates the Autophagic Machinery To Enhance Viral Replication

(2014) M. Granato et al.   JOURNAL OF VIROLOGY

Epstein-Barr Virus Large Tegument Protein BPLF1 Contributes to Innate Immune Evasion through Interference with Toll-Like Receptor Signaling

(2014) Michiel van Gent et al.   PLoS Pathogens

Macroautophagy Proteins Assist Epstein Barr Virus Production and Get Incorporated Into the Virus Particles

(2014) Heike Nowag et al.   EBioMedicine

Caspase-1 Promotes Epstein-Barr Virus Replication by Targeting the Large Tegument Protein Deneddylase to the Nucleus of Productively Infected Cells

(2013) Stefano Gastaldello et al.   PLoS Pathogens

Divergent Roles of Autophagy in Virus Infection

(2013) Abhilash Chiramel et al.   Cells

Cytosolic herpes simplex virus capsids not only require binding inner tegument protein pUL36 but also pUL37 for active transport prior to secondary envelopment

(2012) Malte Sandbaumhüter et al.   CELLULAR MICROBIOLOGY

AP1 is essential for generation of autophagosomes from the trans-Golgi network

(2012) Y. Guo et al.   JOURNAL OF CELL SCIENCE

The C Terminus of the Large Tegument Protein pUL36 Contains Multiple Capsid Binding Sites That Function Differently during Assembly and Cell Entry of Herpes Simplex Virus

(2012) J. Schipke et al.   JOURNAL OF VIROLOGY

p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

(2011) Eisuke Itakura et al.   JOURNAL OF CELL BIOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy

(2010) Weiliang Fan et al.   Autophagy

A deneddylase encoded by Epstein–Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases

(2010) Stefano Gastaldello et al.   NATURE CELL BIOLOGY

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-κB Signalling

(2009) Jed Long et al.   JOURNAL OF MOLECULAR BIOLOGY

A Gammaherpesvirus Ubiquitin-Specific Protease Is Involved in the Establishment of Murine Gammaherpesvirus 68 Infection

(2009) S. Gredmark-Russ et al.   JOURNAL OF VIROLOGY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim

(2009) A. L. Desbien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viruses and autophagy

(2009) Sagar B. Kudchodkar et al.   REVIEWS IN MEDICAL VIROLOGY

Eating the enemy within: autophagy in infectious diseases

(2008) A Orvedahl et al.   CELL DEATH AND DIFFERENTIATION

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH