Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells

Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression

(2020) Niklas Mejhert et al.   MOLECULAR CELL

ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors

(2019) Richard S. Marshall et al.   CELL

HDAC6 regulates lipid droplet turnover in response to nutrient deprivation via p62-mediated selective autophagy

(2019) Yan Yan et al.   Journal of Genetics and Genomics

Autophagy regulates lipid metabolism through selective turnover of NCoR1

(2019) Tetsuya Saito et al.   Nature Communications

Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes

(2019) Micah B. Schott et al.   JOURNAL OF CELL BIOLOGY

Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export

(2019) Saskia Heybrock et al.   Nature Communications

Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux

(2019) Patrick A. Sandoz et al.   PLOS BIOLOGY

TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators

(2018) Julian Nüchel et al.   Autophagy

A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes

(2018) Kirill Bersuker et al.   DEVELOPMENTAL CELL

Fasting and refeeding induces changes in the mouse hepatic lipid droplet proteome

(2018) David A. Kramer et al.   Journal of Proteomics

Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells

(2018) Christina B. K. Jayson et al.   MOLECULAR BIOLOGY OF THE CELL

pH-dependent regulation of SQSTM1/p62 during autophagy

(2018) Do Hoon Kwon et al.   Autophagy

Vacuolar hydrolysis and efflux: current knowledge and unanswered questions

(2018) Katherine R. Parzych et al.   Autophagy

Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models

(2018) Kyeongdae Kim et al.   CIRCULATION RESEARCH

Lysosomal oxidation of LDL alters lysosomal pH, induces senescence, and increases secretion of pro-inflammatory cytokines in human macrophages

(2018) Feroz Ahmad et al.   JOURNAL OF LIPID RESEARCH

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Desmocollin 1 is abundantly expressed in atherosclerosis and impairs high-density lipoprotein biogenesis

(2017) Hong Y Choi et al.   EUROPEAN HEART JOURNAL

Differential proteomics profiling identifies LDPs and biological functions in high-fat diet-induced fatty livers

(2017) Mingwei Liu et al.   JOURNAL OF LIPID RESEARCH

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Cold-inducible RNA-binding protein through TLR4 signaling induces mitochondrial DNA fragmentation and regulates macrophage cell death after trauma

(2017) Zhigang Li et al.   Cell Death & Disease

Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells

(2017) Lin Wang et al.   Scientific Reports

Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress

(2017) Raquel Pascua-Maestro et al.   PLoS Genetics

Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole

(2017) Takuma Tsuji et al.   eLife

AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation

(2017) Arnold Y Seo et al.   eLife

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1

(2017) Karen Y. Fung et al.   Frontiers in Physiology

AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA

(2016) Susmita Kaushik et al.   Autophagy

Stress granules at the intersection of autophagy and ALS

(2016) Zachary Monahan et al.   BRAIN RESEARCH

Mechanistic insights into selective autophagy pathways: lessons from yeast

(2016) Jean-Claude Farré et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition

(2016) Eric W. Deutsch et al.   NUCLEIC ACIDS RESEARCH

MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals

(2015) Jia Yuan et al.   Autophagy

A defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis

(2015) Yuichiro Maeda et al.   Autophagy

Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics

(2015) Angelika S. Rambold et al.   DEVELOPMENTAL CELL

Autophagosomes and lipid droplets: no longer just chewing the fat

(2015) V. Deretic   EMBO JOURNAL

Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis

(2015) T. Shpilka et al.   EMBO JOURNAL

Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeastSchizosaccharomyces pombe

(2015) Akira Doi et al.   GENES TO CELLS

Autophagy at the crossroads of catabolism and anabolism

(2015) Jasvinder Kaur et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of the Proteome of Cytoplasmic Lipid Droplets in Mouse Enterocytes after a Dietary Fat Challenge

(2015) Theresa D’Aquila et al.   PLoS One

miR-23b-3p regulates the chemoresistance of gastric cancer cells by targeting ATG12 and HMGB2

(2015) Y An et al.   Cell Death & Disease

Proteomic analysis of murine testes lipid droplets

(2015) Weiyi Wang et al.   Scientific Reports

Induction of Lysosomal Biogenesis in Atherosclerotic Macrophages Can Rescue Lipid-Induced Lysosomal Dysfunction and Downstream Sequelae

(2014) Roy Emanuel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast

(2014) Chao-Wen Wang et al.   JOURNAL OF CELL BIOLOGY

The Proteome of Cholesteryl-Ester-Enriched Versus Triacylglycerol-Enriched Lipid Droplets

(2014) Victor K. Khor et al.   PLoS One

14-3-3 and aggresome formation: Implications in neurodegenerative diseases

(2014) Baohui Jia et al.   Prion

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

A current perspective of autophagosome biogenesis

(2013) Shusaku T Shibutani et al.   CELL RESEARCH

Lipid droplet autophagy in the yeast Saccharomyces cerevisiae

(2013) Tim van Zutphen et al.   MOLECULAR BIOLOGY OF THE CELL

Monoubiquitination of Ancient Ubiquitous Protein 1 Promotes Lipid Droplet Clustering

(2013) Daniel Lohmann et al.   PLoS One

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

(2012) Jose A. Martina et al.   Autophagy

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

(2012) Xianghai Liao et al.   Cell Metabolism

Characterization of the Lipid Droplet Proteome of a Clonal Insulin-producing β-Cell Line (INS-1 832/13)

(2012) Sara Larsson et al.   JOURNAL OF PROTEOME RESEARCH

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Development of p97 AAA ATPase inhibitors

(2011) Tsui-Fen Chou et al.   Autophagy

Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum

(2011) Dalibor Mijaljica et al.   Autophagy

Cytoskeleton disruption in J774 macrophages: Consequences for lipid droplet formation and cholesterol flux

(2011) Ginny L. Weibel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Microautophagy: lesser-known self-eating

(2011) Wen-wen Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

"Autophagy suite": Atg9 cycling in the cytoplasm to vacuole targeting pathway

(2010) Nobuo Munakata et al.   Autophagy

Autophagy gets a brake

(2010) Itay Koren et al.   Autophagy

Ancient Ubiquitous Protein 1 (AUP1) Localizes to Lipid Droplets and Binds the E2 Ubiquitin Conjugase G2 (Ube2g2) via Its G2 Binding Region

(2010) Johanna Spandl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A guided tour of the Trans-Proteomic Pipeline

(2010) Eric W. Deutsch et al.   PROTEOMICS

A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy

(2009) Tomotake Kanki et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration

(2008) S. Bauer et al.   BIOINFORMATICS

ProteoWizard: open source software for rapid proteomics tools development

(2008) Darren Kessner et al.   BIOINFORMATICS

Autophagy-mediated clearance of aggresomes is not a universal phenomenon

(2008) Esther S.P. Wong et al.   HUMAN MOLECULAR GENETICS