Developmental malformations in Huntington disease: neuropathologic evidence of focal neuronal migration defects in a subset of adult brains

Adherens Junctions: Guardians of Cortical Development

(2020) Lenin Veeraval et al.   Frontiers in Cell and Developmental Biology

Primary Age-Related Tauopathy (PART): Addressing the Spectrum of Neuronal Tauopathic Changes in the Aging Brain

(2020) Richard A. Hickman et al.   Current Neurology and Neuroscience Reports

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1

(2020) Ricardo Mouro Pinto et al.   HUMAN MOLECULAR GENETICS

Huntington’s disease alters human neurodevelopment

(2020) Monia Barnat et al.   SCIENCE

Loss-of-huntingtin in medial and lateral ganglionic lineages differentially disrupts regional interneuron and projection neuron subtypes and promotes Huntington's disease-associated behavioral, cellular and pathological hallmarks

(2019) Mark F. Mehler et al.   JOURNAL OF NEUROSCIENCE

Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription

(2019) Rui Gao et al.   eLife

Abnormal brain development in child and adolescent carriers of mutant huntingtin

(2019) Ellen van der Plas et al.   NEUROLOGY

CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset

(2019) Jong-Min Lee et al.   CELL

Subcortical heterotopic gray matter brain malformations

(2019) Renske Oegema et al.   NEUROLOGY

Multinodular and vacuolating neuronal tumor of the cerebrum is a clonal neoplasm defined by genetic alterations that activate the MAP kinase signaling pathway

(2018) Melike Pekmezci et al.   ACTA NEUROPATHOLOGICA

A role for autophagy in Huntington's disease

(2018) Katherine R. Croce et al.   NEUROBIOLOGY OF DISEASE

DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage

(2018) Tamara Maiuri et al.   DNA AND CELL BIOLOGY

Somatic mosaicism and neurodevelopmental disease

(2018) Alissa M. D’Gama et al.   NATURE NEUROSCIENCE

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

(2017) Ryan G Lim et al.   NATURE NEUROSCIENCE

Aging and neurodegeneration are associated with increased mutations in single human neurons

(2017) Michael A. Lodato et al.   SCIENCE

Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis

(2017) Taejeong Bae et al.   SCIENCE

Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex

(2016) Tamara Maiuri et al.   HUMAN MOLECULAR GENETICS

Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease

(2016) Eduardo E. Arteaga-Bracho et al.   NEUROBIOLOGY OF DISEASE

The Biology of Huntingtin

(2016) Frédéric Saudou et al.   NEURON

Concurrent neurodegenerative pathologies in periventricular nodular heterotopia

(2015) Kevin F. Bieniek et al.   ACTA NEUROPATHOLOGICA

Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia

(2015) Gewei Lian et al.   Frontiers in Cellular Neuroscience

Somatic Mutations in Cerebral Cortical Malformations

(2014) Saumya S. Jamuar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multinodular and Vacuolating Neuronal Tumors of the Cerebrum: 10 Cases of a Distinctive Seizure-Associated Lesion

(2013) Jason T. Huse et al.   BRAIN PATHOLOGY

Mutations of the Huntington’s Disease Protein Impact on the ATM-Dependent Signaling and Repair Pathways of the Radiation-Induced DNA Double-Strand Breaks: Corrective Effect of Statins and Bisphosphonates

(2013) Mélanie L. Ferlazzo et al.   MOLECULAR NEUROBIOLOGY

Somatic Mutation, Genomic Variation, and Neurological Disease

(2013) A. Poduri et al.   SCIENCE

A developmental and genetic classification for malformations of cortical development: update 2012

(2012) A. James Barkovich et al.   BRAIN

Development and neurodegeneration: Turning HD pathogenesis on its head

(2012) K. Marder et al.   NEUROLOGY

Measures of growth in children at risk for Huntington disease

(2012) J. K. Lee et al.   NEUROLOGY

Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment

(2010) Peggy C. Nopoulos et al.   BRAIN

Striatal and white matter predictors of estimated diagnosis for Huntington disease

(2010) Jane S. Paulsen et al.   BRAIN RESEARCH BULLETIN

Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis

(2010) Juliette D. Godin et al.   NEURON

Neuroanatomic Profile of Polyglutamine Immunoreactivity in Huntington Disease Brains

(2009) Emily S. Herndon et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Electronic tracking of human brain samples for research

(2008) Christian E. Keller et al.   CELL AND TISSUE BANKING

Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia

(2008) Russell J. Ferland et al.   HUMAN MOLECULAR GENETICS