Review
Biochemistry & Molecular Biology
Sara C. Pereira, Pedro F. Oliveira, Sonia Rodrigues Oliveira, Maria de Lourdes Pereira, Marco G. Alves
Summary: Male reproductive tissues are sensitive to environmental stressors, with chromium compounds potentially impacting spermatogenesis. However, long-term effects of chromium picolinate and its impact on the antioxidant system of treated subjects remain poorly studied.
Article
Obstetrics & Gynecology
Joemy M. Ramsay, Kiarad Fendereski, Joshua J. Horns, James A. Vanderslice, Heidi A. Hanson, Benjamin R. Emery, Joshua A. Halpern, Kenneth I. Aston, Elisabeth Ferlic, James M. Hotaling
Summary: This retrospective cohort study found associations between chronic exposure to industrial air pollution and male fertility through semen parameters. Several chemical classes were significantly associated with azoospermia, decreased total motility, and volume. Additionally, socioeconomic disadvantage was linked to lower semen parameters. More research is needed to explore additional social and exposure factors and the risks posed by the studied chemicals to male reproductive health.
FERTILITY AND STERILITY
(2023)
Article
Food Science & Technology
Pascal Philibert, Isabelle Stevant, Stephanie Dejardin, Melissa Girard, Eli Sellem, Quentin Durix, Aurelie Messager, Anne-Alicia Gonzalez, Xavier Mialhe, Alain Pruvost, Francis Poulat, Brigitte Boizet-Bonhoure
Summary: This study investigated the adverse effects of NSAIDs and EE2 mixtures on the reproductive organ development and fertility in mice. The results showed that exposure to these mixtures altered reproductive organ maturation, estrous cyclicity, and spermiogenesis in mice. Transcriptomic analysis revealed changes in gene expression patterns and associated pathways. These findings are important for understanding the adverse effects of these pharmaceuticals on reproductive health.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Review
Endocrinology & Metabolism
Tao Li, Yunjin Bai, Yiting Jiang, Kehua Jiang, Ye Tian, Jiang Gu, Fa Sun
Summary: Circadian rhythm disturbances, such as night shiftwork, insufficient sleep, and poor sleep quality, have been found to impair sperm quality and increase the risk of male infertility. However, there is a lack of research on the impacts of light, body temperature, and circadian/circannual rhythms. Understanding how circadian disturbances regulate male fertility is important for improving infertility.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Environmental Sciences
XueXia Liu, ZhiXin Wang, Fujun Liu
Summary: Mice treated with BPA exhibited decreased sperm quality, lower serum testosterone levels, and a sub-fertile phenotype, mainly due to impaired germ cell proliferation. BPA had a concentration-dependent inhibition effect on germ cell proliferation, leading to reduced male fertility.
Article
Zoology
Mwajabu SELEMANI, Rhodes H. MAKUNDI, Apia W. MASSAWE, Ginethon MHAMPHI, Loth S. MULUNGU, Steven R. BELMAIN
Summary: Research shows that contraceptive hormones levonorgestrel and quinestrol can reduce pregnancy rate and litter size in black rats, with potential impacts on male reproductive organs. Further studies are needed to investigate the duration and reversibility of these effects.
INTEGRATIVE ZOOLOGY
(2022)
Article
Pharmacology & Pharmacy
Zhaolan Wei, Yunyi Wang, Shuwei Wang, Jing Xie, Qi Han, Mingqing Chen
Summary: Exposure to microplastics has negative effects on the reproductive systems and fertility of mice. Male mice experience reduced sperm quantity and increased sperm deformity, while female mice experience decreased ovary size and follicle number. Additionally, microplastic exposure alters hormone levels and leads to reduced pregnancy rates and fewer embryos in mice.
Review
Medicine, General & Internal
Agnieszka Markiewicz-Gospodarek, Paulina Wdowiak, Marcin Czeczelewski, Alicja Forma, Jolanta Flieger, Jacek Januszewski, Elzbieta Radzikowska-Buchner, Jacek Baj
Summary: The SARS-CoV-2 infection can potentially impact the reproductive systems of both females and males, potentially leading to disruptions in human fertility.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Silvia Moreira, Ricardo Silva, David F. Carrageta, Marco G. Alves, Vicente Seco-Rovira, Pedro F. Oliveira, Maria de Lourdes Pereira
Summary: Carbamates, widely used as pesticides, have both medical applications and adverse effects on the male reproductive system. Their inhibitory effect on acetylcholine hydrolyzation can lead to male fertility problems and disrupt the male endocrine system. The molecular mechanisms behind these effects are not fully understood.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Obstetrics & Gynecology
Gabriela Caetano, Ines Bozinovic, Charlotte Dupont, Damien Leger, Rachel Levy, Nathalie Sermondade
Summary: Results of the study suggest that sleep parameters may affect female and male reproductive functions, with short sleep duration, evening chronotype, or shift/night work schedules potentially impacting fertility and IVF outcomes. However, due to heterogeneous study methodologies, the results were difficult to compare.
FERTILITY AND STERILITY
(2021)
Review
Biochemistry & Molecular Biology
Andrea Lopez-Botella, Irene Velasco, Maribel Acien, Paula Saez-Espinosa, Jose-Luis Todoli-Torro, Raquel Sanchez-Romero, Maria Jose Gomez-Torres
Summary: Heavy metals are endocrine disruptors that negatively affect endocrine functions and may impact male fertility. Developing adequate assessment tools for heavy metals could be important in diagnosing and treating human male fertility. Clinical trials could help confirm the role of heavy metals in human male fertility diagnosis.
Review
Medicine, Research & Experimental
Soudeh Ghafouri-Fard, Hamed Shoorei, Atefe Abak, Mohammad Seify, Mahdi Mohaqiq, Fatemeh Keshmir, Mohammad Taheri, Seyed Abdulmajid Ayatollahi
Summary: The treatment of cancer in young adults can have detrimental effects on the reproductive system, particularly on male germ cells. Lack of appropriate fertility preservation treatments in affected children calls for the introduction of methods to mitigate the harmful effects of chemotherapeutic agents, including the potential protective effects of antioxidants.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Review
Biochemistry & Molecular Biology
Marcela Arteaga-Silva, Edith Arenas-Rios, Herlinda Bonilla-Jaime, Pablo Damian-Matzumura, Ofelia Limon-Morales, Joel Hernandez-Rodriguez, Darla Marquez-Aguiluz
Summary: Cadmium is a form of anthropogenic pollution in industrialized countries, posing a public health problem and affecting male reproduction as an endocrine disruptor. Its toxic effects on male reproductive functions are mediated through altering mitochondrial function and generating free radicals.
FRONTIERS IN BIOSCIENCE-LANDMARK
(2021)
Review
Urology & Nephrology
Daniel E. Nassau, Jordan C. Best, Eliyahu Kresch, Daniel C. Gonzalez, Kajal Khodamoradi, Ranjith Ramasamy
Summary: The COVID-19 pandemic caused by SARS-CoV-2 has disproportionately affected men, with androgens potentially playing a role in more severe disease. However, there are still many unanswered questions regarding the specific mechanisms by which COVID-19 impacts male reproductive organs and the long-term consequences on male reproductive health.
Review
Agriculture, Dairy & Animal Science
Rhesti Indriastuti, Berlin Pandapotan Pardede, Asep Gunawan, Mokhamad Fakhrul Ulum, Raden Iis Arifiantini, Bambang Purwantara
Summary: Infertility is a problem in the livestock industry, leading to long calving interval periods and increased operational costs. Traditional methods for assessing sperm quality are not accurate enough for predicting male fertility potential, but transcriptomic analysis provides a more accurate prediction method.
