Role of Exendin-4 in Brain Insulin Resistance, Mitochondrial Function, and Neurite Outgrowth in Neurons under Palmitic Acid-Induced Oxidative Stress

Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins

(2019) Norbert Bencsik et al.   Scientific Reports

GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome

(2019) Kadri Seppa et al.   Scientific Reports

Glucagon-like peptide-1 suppresses neuroinflammation and improves neural structure

(2019) Gwangho Yoon et al.   PHARMACOLOGICAL RESEARCH

Palmitoleic acid (16:1n7) increases oxygen consumption, fatty acid oxidation and ATP content in white adipocytes

(2018) Maysa M. Cruz et al.   Lipids in Health and Disease

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration

(2018) Alban Latremoliere et al.   Cell Reports

Exendin-4 promotes actin cytoskeleton rearrangement and protects cells from Nogo-A-Δ20 mediated spreading inhibition and growth cone collapse by down-regulating RhoA expression and activation via the PI3K pathway

(2018) Fei Zhao et al.   BIOMEDICINE & PHARMACOTHERAPY

It takes a village to raise a branch: Cellular mechanisms of the initiation of axon collateral branches

(2017) Lorena Armijo-Weingart et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a

(2017) Matteo Spinelli et al.   Nature Communications

Palmitic Acid-BSA enhances Amyloid-β production through GPR40-mediated dual pathways in neuronal cells: Involvement of the Akt/mTOR/HIF-1α and Akt/NF-κB pathways

(2017) Jeong Yeon Kim et al.   Scientific Reports

Actin filament-microtubule interactions in axon initiation and branching

(2016) Almudena Pacheco et al.   BRAIN RESEARCH BULLETIN

Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain

(2016) Gurdeep Marwarha et al.   CELLULAR SIGNALLING

Tau Deletion Prevents Stress-Induced Dendritic Atrophy in Prefrontal Cortex: Role of Synaptic Mitochondria

(2016) Sofia Lopes et al.   CEREBRAL CORTEX

Neuronal polarity: remodeling microtubule organization

(2016) Sam FB van Beuningen et al.   CURRENT OPINION IN NEUROBIOLOGY

Dendritic spine actin dynamics in neuronal maturation and synaptic plasticity

(2016) Iryna Hlushchenko et al.   Cytoskeleton

FoxO regulates microtubule dynamics and polarity to promote dendrite branching in Drosophila sensory neurons

(2016) James C. Sears et al.   DEVELOPMENTAL BIOLOGY

Structural and functional plasticity of dendritic spines - root or result of behavior?

(2016) C. D. Gipson et al.   GENES BRAIN AND BEHAVIOR

Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation

(2016) K. W. Yau et al.   JOURNAL OF NEUROSCIENCE

RNA Interference Silencing of Glycogen Synthase Kinase 3β Inhibites Tau Phosphorylation in Mice with Alzheimer Disease

(2016) Hong Bian et al.   NEUROCHEMICAL RESEARCH

Calcium, Reactive Oxygen Species, and Synaptic Plasticity

(2016) Cecilia Hidalgo et al.   PHYSIOLOGY

Mushroom spine dynamics in medium spiny neurons of dorsal striatum associated with memory of moderate and intense training

(2016) Paola C. Bello-Medina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

(2016) Carlos Rodriguez-Navas et al.   Molecular Metabolism

CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation

(2016) Xiaodong Yan et al.   PLoS One

Neuronal Splicing Regulator RBFOX3 (NeuN) Regulates Adult Hippocampal Neurogenesis and Synaptogenesis

(2016) Yi-Sian Lin et al.   PLoS One

Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

(2015) Dania C. Liemburg-Apers et al.   ARCHIVES OF TOXICOLOGY

ROS Produced by NOX2 Controls In Vitro Development of Cerebellar Granule Neurons Development

(2015) Mauricio Olguín-Albuerne et al.   ASN Neuro

Liraglutide Promotes Cortical Neurite Outgrowth via the MEK–ERK Pathway

(2015) Meng Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Efficacy of glucagon-like peptide-1 mimetics for neural regeneration

(2015) Kazunori Sango et al.   Neural Regeneration Research

Synapses, spines and kinases in mammalian learning and memory, and the impact of aging

(2015) Eddy A. van der Zee   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effects of high-fat diet exposure on learning & memory

(2015) Zachary A. Cordner et al.   PHYSIOLOGY & BEHAVIOR

Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice

(2015) Mark A. Smith et al.   Cell Reports

Obesity and neuroinflammation: A pathway to cognitive impairment

(2014) Alyson A. Miller et al.   BRAIN BEHAVIOR AND IMMUNITY

Transcription factors and effectors that regulate neuronal morphology

(2014) C. Santiago et al.   DEVELOPMENT

Palmitic acid affects proliferation and differentiation of neural stem cells in vitro

(2014) Zhen Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

The longer-term impacts of Western diet on human cognition and the brain

(2013) Heather Francis et al.   APPETITE

Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects

(2013) K. T. Tonks et al.   DIABETOLOGIA

Altered neural connectivity in excitatory and inhibitory cortical circuits in autism

(2013) Basilis Zikopoulos et al.   Frontiers in Human Neuroscience

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXO1 Mediates the Autocrine Effect of Endothelin-1 on Endothelial Cell Survival

(2012) Vincenza Cifarelli et al.   MOLECULAR ENDOCRINOLOGY

Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases

(2012) Li Liu et al.   NEUROBIOLOGY OF AGING

Palmitic acid increases apoptosis of neural stem cells via activating c-Jun N-terminal kinase

(2012) Qiuhuan Yuan et al.   Stem Cell Research

Insulin receptor substrate 2 is a negative regulator of memory formation

(2011) E. E. Irvine et al.   LEARNING & MEMORY

Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies

(2011) K. J. Anstey et al.   Obesity Reviews

Increased Brain Fatty Acid Uptake in Metabolic Syndrome

(2010) A. Karmi et al.   DIABETES

Central Insulin Signaling Is Attenuated by Long-Term Insulin Exposure via Insulin Receptor Substrate-1 Serine Phosphorylation, Proteasomal Degradation, and Lysosomal Insulin Receptor Degradation

(2009) Christopher M. Mayer et al.   ENDOCRINOLOGY

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease

(2009) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

PPARγ stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss

(2009) Gianluca Miglio et al.   NEUROCHEMISTRY INTERNATIONAL

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Role of Central Nervous System Glucagon-Like Peptide-1 Receptors in Enteric Glucose Sensing

(2008) C. Knauf et al.   DIABETES

Activation and reversal of lipotoxicity in PC12 and rat cortical cells following exposure to palmitic acid

(2008) Frankis G. Almaguel et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory

(2003) J. David Sweatt   JOURNAL OF NEUROCHEMISTRY